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UH Case Medical Center, CardioKinetix reveal promising data for treatment for heart failure
Date:5/18/2012

p-value=0.74). The combined rate of all-cause death and hospitalization due to worsening heart failure was 16.1 percent at one year and 32.3 percent at two years. The rate of cardiac death was 6.5 percent at two years. These outcomes compare favorably with current medical therapy in a similar high-risk patient population.

"We are extremely pleased with the two-year clinical results from the Parachute implant. This data supports the design of our randomized pivotal trial, in which we anticipate a potential reduction of death and hospitalization due to worsening heart failure on the order of 30 to 50 percent for patients treated with the Parachute system compared to optimal medical therapy," said William T. Abraham, MD, director of the Division of Cardiovascular Medicine and professor of internal medicine, physiology and cell biology at The Ohio State University Medical Center who was also part of the first U.S. trial. "This innovative device has the potential to bring together two cardiology disciplines heart failure and interventional cardiology to address a significant unmet need in heart failure."

"The presentation of this long-term clinical data is an exciting milestone for CardioKinetix," said Maria Sainz, president and CEO of CardioKinetix. "We look forward to gathering additional evidence in our European trials of the clinical benefits of the Parachute and as we prepare to start our pivotal trial with the device, which we believe holds the potential to improve the lives of tens of thousands of patients around the world."

After a heart attack, many patients experience enlargement of the left ventricle of the heart, causing a decrease in cardiac output that results in heart failure symptoms such as fatigue and shortness of breath. The healthy portion of the heart not affected by the heart attack has to compensate for the loss in output and becomes overloaded overtime. Current treatment options for patients whose heart has enlarged
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Contact: Mike Ferrari
mike.ferrari@uhhospitals.org
216-844-7239
University Hospitals Case Medical Center
Source:Eurekalert

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