Navigation Links
UGA researchers propose model for disorders caused by improper transmission of chromosomes
Date:8/16/2009

Xuexian Li.

Irregularities in chromosome number are usually caused during a biological event called meiosis, in which the number of chromosomes per cell is halved and, in animals, results in the formation of gametes or sex cells. While the biology of meiosis has been known for more than a century, major questions remain about how all the constituent cell parts must coordinate to make the process successful.

During the two stages of meiosis, chromosomes are first separated by type, ensuring that only one of each gene is represented and then separated in half again in preparation for fertilization. The authors showed that the first stage is orchestrated in part by the kinetochore that attaches chromosomes to the rest of the cell. When they suppressed a kinetochore protein called MIS12, the chromosomes no longer separated by type and jumped to the second stage before completing the first. These failures closely mimic those seen in eggs from older women.

The cell division processes that Dawe and Li studied have implications for other diseasessuch as canceras well. And yet a genuine payoff may come in the form of genetically improved lines of corn.

Dawe's work opens the possibility of a more positive outcome: the ability to engineer so-called "artificial chromosomes" with useful genes into corn varieties. Though that may be years off, it could offer a way to create lines that could resist drought, disease and insect pests without harming the environment.

Researchers are racing to design artificial chromosomes that behave like natural ones. With such an engineered chromosome, the positives traits researchers could give to corn plants would be almost limitless.

"You could really put genes in there at will, stacking traits that would make the plants able to withstand problems that now limit production greatly all over the world," said Dawe. "But to get from theory to practice, we will need a much clearer understanding
'/>"/>

Contact: Kelly Dawe
kelly@plantbio.uga.edu
706-542-1658
University of Georgia
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
2. NIH-funded researchers sequence exomes of 12 people
3. USC researchers identify regulatory genetic sequences that may predict risk for prostate cancer
4. K-State lab gives researchers the tools to study porcine circovirus associated diseases
5. Hebrew U. researchers shed light on the brain mechanism responsible for processing of speech
6. SLAC researchers reveal the dance of water
7. McGill/JGH researchers successfully reverse multiple sclerosis in animals
8. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
9. Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding
10. University of Hawaii at Manoa researchers reveal ocean acidification at Station ALOHA
11. UBC researchers find first-ever wanderlust gene in tiny bony fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... articles posted online ahead of print 9 ... of geoscience subdisciplines, including minerals exploration, archaeology, planetary ... include Siberia; the Sumatran subduction margin; the Monte ... and the Southeastern U.S. Atlantic Margin. Brief highlights ... tectonics;, 2. The clear fingerprint of ice ages ...
(Date:5/18/2013)... today at Digestive Disease Week (DDW) explores new discoveries ... of coffee on autoimmune disease and palliative care for ... been associated with reduced risk of fibrosis, a new ... java each month also correlate with lower risk for ... Clinic, Rochester, MN, linked coffee consumption with reduced risk ...
(Date:5/17/2013)... of New Jersey, and City University of New York ... that effectively clears organisms to be viewed under ... hydrate, which is one of the few high-quality clearing ... the Drug Enforcement Administration (DEA) due to its use ... are vital for viewing organisms under a microscope. Without ...
Breaking Biology News(10 mins):New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 3New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 4New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 5New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 6New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 7New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 8New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 9New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 10New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 11Coffee consumption associated with reduced risk of autoimmune liver disease 2New formula invented for microscope viewing, substitutes for federally controlled drug 2New formula invented for microscope viewing, substitutes for federally controlled drug 3
... more to fighting infection than just clearing the body of ... the host,s tissue caused, very frequently, by toxins produced by ... clears those pathogens. Indeed, it is the damage inflicted to ... the lethal outcome of some infectious diseases. , The ...
... the current issue of Science , researchers at Michigan ... light on how easy it can be for diseases to ... time how the virus called "Lambda" evolved to find a ... four mutations to accomplish. This virus infects bacteria, in particular ...
... -- (Jan. 26, 2012) -- Like a magician employing sleight ... player in diabetes, cancer and aging -- draws the eye ... subtle, more crucial action takes place somewhere else. Using ... Rice University and the University of California, San Diego (UCSD) ...
Cached Biology News:European Research Council supports search for regulators of tissue damage 2MSU researchers show how new viruses evolve, and in some cases, become deadly 2Rice, UCSD scientists probe form, function of mysterious protein 2Rice, UCSD scientists probe form, function of mysterious protein 3
(Date:5/20/2013)... May 20, 2013  Dr. Gerald Zon ... acid research, recently launched a new blog in conjunction ... ( zon.trilinkbiotech.com ), focuses on what,s trending in the ... industry thought leaders, discussions of research presented at conferences ... Dr. Zon (PhD Princeton University 1971) developed ...
(Date:5/20/2013)... With bed bugs' presence come problems in various terms. ... to be eliminated, one must make sure that the bed ... so to help bed bug sufferers get that done, it ... bugs without using harmful pesticides. In it, the company ... Bug Bully. , According to My Cleaning Products, contrary to ...
(Date:5/20/2013)... HILL, N.C. , May 20, 2013 /PRNewswire/ ... company focused on developing differentiated antibiotics to meet ... infections, today announced that it presented data at ... in Philadelphia demonstrating the ... levofloxacin in Cempra,s prior Phase 2 clinical trial ...
(Date:5/20/2013)... BOSTON , May 20, 2013 Rhythm ... clinical trial of RM-131, the company,s novel ghrelin agonist ... diabetic patients. The trial demonstrated that RM-131 significantly accelerates ... in type 1 diabetic patients with diabetic gastroparesis. The ... conference in Orlando and recently ...
Breaking Biology Technology:Dr. Gerald 'Jerry' Zon Launches New Blog for TriLink BioTechnologies 2New Non Pesticide Discovery on How to Get Rid of Bed Bugs Tipped by My Cleaning Products 2Cempra Presents Post-Phase 2 Analysis of Solithromycin's Efficacy and Safety Results from Patients with Community Acquired Bacterial Pneumonia (CABP) 2Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 2Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 3
... Sept. 1 /PRNewswire-Asia-FirstCall/ -- China Kangtai Cactus,Biotech Inc. ... manufacturer and marketer of a variety of cactus-based ... successfully completed the trial,production of cactus-based cigarettes and ... in 2009: (i) low nicotine and (ii) zero ...
... ANNAPOLIS, Md., Sept. 1 PharmAthene, Inc. (NYSE Amex: ... against biological and chemical threats, announced today that management will ... 2009. The Company is scheduled to present on Thursday, ... Salon (5th Floor) at the New York Palace Hotel, New ...
... FORT LAUDERDALE, Fla., Sept. 1 OmniComm Systems, Inc. (OTC ... data capture (EDC) solutions for clinical trials, and ... announced today that three additional clinical research organizations ... the CRO Preferred Program. The partnership allows CROs in the ...
Cached Biology Technology:China Kangtai Cactus Biotech to Launch Patented Cactus-based Low Tar, Low or Zero Nicotine Cigarettes 2China Kangtai Cactus Biotech to Launch Patented Cactus-based Low Tar, Low or Zero Nicotine Cigarettes 3OmniComm Systems Inc. Expands Its Successful CRO Preferred Program(TM) By Signing On Three New CRO Partners 2OmniComm Systems Inc. Expands Its Successful CRO Preferred Program(TM) By Signing On Three New CRO Partners 3
Rabbit polyclonal to Myosin VIIa (rating: *****) ( Abpromise for all tested applications). entrezGeneID: 4647 SwissProtID: Q13402...
Rabbit polyclonal to GPCR G2A ( Abpromise for all tested applications). entrezGeneID: 29933 SwissProtID: Q9UNW8...
6-keto Prostaglandin F1α EIA Antiserum 6-keto-PGF1alpha EIAs prostaglandins antisera enzyme immunoassays reagents 6-keto-PGF1.alpha....
...
Biology Products: