Navigation Links
UGA researchers develop rapid diagnostic test for common type of pneumonia
Date:12/15/2010

Athens, Ga. University of Georgia researchers have developed a technique that can diagnose a common type of pneumonia within minutes, potentially replacing existing tests that can take several days for results.

The researchers, whose findings are detailed online in the journal PLoS ONE, detected Mycoplasma pneumoniae, which causes atypical or "walking pneumonia," in true clinical samples with over 97 percent accuracy using a recently-developed nanotechnology-based platform.

"If you can make a positive identification from a 10-minute test, then appropriate antibiotics can be prescribed, limiting both the consequences in that patient and the likelihood that it will spread to others," said lead-author Duncan Krause, a professor in the department of microbiology in the UGA Franklin College of Arts and Sciences.

Krause and his colleagues built upon an existing technology called surface-enhanced Raman spectroscopy, which works by detecting spectral signatures of a near-infrared laser as it scatters off a biological specimen. They were able to enhance the Raman signal by using silver nanorod arrays to detect the tiny bacteria in throat swab specimens.

Krause, who also directs the interdisciplinary UGA Faculty of Infectious Diseases, compared the nanorod array developed by collaborator Yiping Zhao, director of the UGA Nanoscale Science and Engineering Center, to a brush with densely packed bristles, where each of the tiny silver rods extends out at a specific angle. The sample, such as bacteria from a throat swab, penetrates among the bristles, where the spectral signature produced by the laser is amplified and then analyzed by a computer program.

Krause noted that infections due to M. pneumoniae are very common yet difficult to diagnose. The bacterium is a major cause of respiratory disease in humans and the leading cause of pneumonia in older children and young adults.

"Walking pneumonia feels li
'/>"/>

Contact: Duncan Krause
dkrause@uga.edu
706-542-2671
University of Georgia
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Freshwater sustainability challenges shared by Southwest and Southeast, researchers find
2. MGH researchers develop faster method of engineering zinc-finger nucleases
3. Researchers discover how natural drug fights inflammation
4. Researchers devise computer model for projecting severity of flu season
5. NIH awards $6.4 million to Case Western Reserve School of Medicine researchers
6. Researchers discover a way to delay Christmas tree needle loss
7. Researchers: Include data about societal values in endangered species decisions
8. UT Southwestern researchers uncover culprits in life-threatening clotting disorder
9. SomaLogic researchers describe revolutionary new approach to protein analysis and application to early diagnosis of lung cancer
10. Researchers describe first functioning lipidome of mouse macrophage
11. Researchers find link between sugar, diabetes and aggression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... scientists from around the world today issued a stark ... of one or two generations, the majority of the ... the handicap of severe pressure on fresh water, an ... substitute. This handicap will be self-inflicted and is, we ... chronic underlying problems led by mismanagement and sent a ...
(Date:5/23/2013)... , Automated conserved noncoding sequence ... evolution among grasses , Within the genome of ... that undergo little change in position and sequence over ... proteins. Some of these evolutionarily stable sequences, so-called conserved ... of other genes or the condensation of chromosomes, but ...
(Date:5/23/2013)... popular fruit, can be made both better-tasting and longer-lasting ... , "Working with GM tomatoes that are different to ... compound, allows us to pinpoint exactly how to breed ... John Innes Centre. , The research could also lead ... life characteristics because even higher levels of the compounds ...
Breaking Biology News(10 mins):A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 2A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 3A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 4Frontiers news briefs: May 23 2Frontiers news briefs: May 23 3The world's favorite fruit only better-tasting and longer-lasting 2
... pinpointed a set of common variations in human DNA ... who carry them. Some of these variations are more ... future studies examining whether lupus is more prevalent among ... study. Also, the findings point to various drug ...
... is available in French . , A ... small differences between individuals at the DNA level can ... proteins. These, in turn, are responsible for the vast ... study, part of the Genome Regulators in Disease (GRID) ...
... Centre for Cancer Research at Cardiff University have made ... save the lives of women who become resistant to ... such as tamoxifen have been a huge success in ... the drugs either fail to work, or after an ...
Cached Biology News:DNA variations signal lupus risk 2DNA variations signal lupus risk 3Tiny genetic differences have huge consequences: McGill researchers 2Further breakthroughs for breast cancer patients 2
(Date:5/23/2013)... , May 23, 2013 BioTrends ... and advisory firms for specialized biopharmaceutical issues, finds ... and infectious disease specialists reported that in the ... (e.g., intentionally delaying treatment) in anticipation of the ... six months ago, when only 6 percent reported ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 The New ... STEM industries, Black Data Processing Associates (BDPA), is hosting ... June 8, 2013. This all-day event will encourage students ... learn the ins and outs from many of the ... p.m. at the New Jersey Institute of Technology, the ...
(Date:5/23/2013)... 23, 2013 Pusan National University Yangsan ... biotherapeutics and contract research company focused on research ... announced today a publication reporting the induction of ... oncolytic and immunotherapeutic vaccinia JX-594 (pexastimogene devacirepvec; Jennerex ... in the May 15 th , 2013 issue ...
(Date:5/23/2013)... 23, 2013 Bed bugs compromised ... had already confirmed it. Meanwhile, My Cleaning Products offered complimentary ... victims fight the pests without using harmful chemical elements. ... 15, 2013, the affected building was actually a dormitory ... was said made on May 13 and bed bug presence ...
Breaking Biology Technology:The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3Penn State Dorm Infested with Bed Bugs, My Cleaning Products Offers Complimentary Sample of Bed Bug Spray to Help Bed Bug Victims 2
... 11 /PRNewswire/ - Trillium Therapeutics Inc. (TTI), a biopharmaceutical ... entered into two definitive license agreements with University Health Network ... Toronto, Ontario , granting Trillium exclusive worldwide rights to commercialize ... transplantation and cancer. , ...
... most important technological innovation during human history. This genetic ... used individuals carrying favorable gene variants for breeding purposes. ... international team led by researchers at Uppsala University has ... of the domestic chicken. The domestic chicken has ...
... ... ... , ... , , , , ...
Cached Biology Technology:Trillium expands immunology pipeline and enters stem cell field through in-licensing of two new programs 2Trillium expands immunology pipeline and enters stem cell field through in-licensing of two new programs 3Scientific breakthrough in genetic studies of animal domestication 2Toxikon Corporation Hosts Extractables and Leachables Spring Seminar 2Toxikon Corporation Hosts Extractables and Leachables Spring Seminar 3
A set of five peptides which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
... System is the only PCR system that ... every time. It provides accuracy, consistency, and ... or the property of the DNA templates. ... Mix, a unique blend of thermostable enzymes ...
ID clarifier: With ethidium bromide (50 μg/ml)...
Extremely high efficiency packaging extracts useful for transfecting our EpiFOS™ or CopyControl™ Fosmids, or any DNA vector with cos sites. A tremendous value when conpared to the competition...
Biology Products: