"This grant reflects NIH's recognition of the excellence of Dr. Pahor's work in this area over the past 10 years," said David S. Guzick, M.D., Ph.D., UF's senior vice president for health affairs and president of the UF&Shands Health System. "It represents the kind of translational research that UF will increasingly be in a position to conduct."
UF is the coordinating center and a field site for the LIFE study, with other field sites at Northwestern University, Pennington Biomedical Research Center a campus of the Louisiana State University system, Stanford University, Tufts University, the University of Pittsburgh, Wake Forest University Health Sciences and Yale University.
Recruitment will begin in early 2010. Eligible participants will be randomly assigned either to take part in a program of moderate-intensity physical activity or a health education program on successful aging. Individuals will be followed for up to three-and-a-half years.
It will be the largest randomized controlled trial ever conducted on physical activity in older adults, and the size of the study will allow scientists to examine the effect of physical activity on a large number of outcomes in ways that have not been possible before.
Primarily, the study seeks to gauge whether there are long-term effects of physical activity interventions on major mobility disability. Investigators will also examine the effects of physical activity on a number of factors, including cognitive function, serious fall injuries, disability in basic activities of daily living, cardiovascular events and hospitalization and nursing home admission. They will also examine quality-of-life measures such as depression symptoms, sleep quality, stress and satisfaction w
|Contact: Czerne M. Reid|
University of Florida