Navigation Links
UF scientists reveal how dietary restriction cleans cells
Date:8/23/2007

GAINESVILLE, Fla. Reduce, recycle and rebuild is as important to the most basic component of the human body, the cell, as it is to the environment.

And a University of Florida study shows just how much the body benefits when it goes green, at least if youre a rat: Cutting calories helps rodents live longer by boosting cells ability to recycle damaged parts so they can maintain efficient energy production.

Caloric restriction is a way to extend life in animals. If you give them less food, the stress of this healthy habit actually makes them live longer, said Christiaan Leeuwenburgh, Ph.D., chief of the division of biology of aging in UFs Institute on Aging.

Understanding how the process works at the cellular level in rodents could help scientists develop drugs that mimic the process in humans, Leeuwenburgh added.

How does it work? During the aging process, free radicals highly reactive byproducts of our cells respiration wreak havoc on our cellular machinery. Mitochondria, the tiny power plants that keep a cell functioning, are especially vulnerable to this type of damage.

The effects can be disastrous if malfunctioning mitochondria arent removed, they begin to spew out suicidal proteins that prompt the entire cell to die. Cell death, on a whole-body scale, is what aging is all about.

Fortunately, younger cells are adept at reducing, recycling and rebuilding.

In this process, damaged mitochondria are quickly swallowed up and degraded. The broken down pieces are then recycled and used to build new mitochondria. However, older cells are less adept at this process, so damaged mitochondria tend to accumulate and contribute to aging.

Cell survival is dependent upon the ability of the cell to reduce and recycle by a mechanism called autophagy, said William Dunn Jr., Ph.D., a professor of anatomy and cell biology in UFs College of Medicine and senior author of the study, which was published
'/>"/>

Contact: Ann Griswold
anngriswold@gmail.com
352-273-5819
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
3. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
4. UAB scientists discover the origin of a mysterious physical force
5. Fox Chase Cancer Center scientists identify immune-system mutation
6. Scientists Replicate Hepatitis C Virus in Laboratory
7. Scientists detect probable genetic cause of some Parkinsons disease cases
8. Scientists find missing enzyme for tuberculosis iron scavenging pathway
9. Scientists seek answers on what activates deadly anthrax spores
10. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
11. Scientists collaborate to assess health of global environment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... healthy women differ from bacteria in women with ... from Loyola University Chicago Stritch School of Medicine. ... in the American Society for Microbiology,s online journal ... play a role in female urinary health. , ... poorly understood, condition with symptoms similar to urinary ...
(Date:7/9/2014)... the Spanish National Cancer Research Centre (CNIO) have discovered ... also regulates cell division in stratified epitheliathose that form ... the oesophagus or the vaginain adult organisms. According to ... Nature Communications , this factor could also play ... stratified epithelia of the oesophagus and skin. , The ...
(Date:7/9/2014)... Researchers studying critically ill children with traumatic injuries ... patients are likely to develop a hospital-acquired infection. ... Hospital and published online in June in the ... larger efforts that could lead to the clinical ... to prevent or reverse immune system damage following ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Immune function predicts infection risk among child trauma patients 2Immune function predicts infection risk among child trauma patients 3
... (January 24, 2014) A new study published in ... egg production has increased over the past 50 years, the ... footprint. Researchers conducted a lifecycle analysis of U.S. egg production ... the complete lifecycle from crops to hens to the farm ...
... novel high-throughput screening process, scientists have for the first time ... a toxic eye protein that can lead to early onset ... can damage the eye,s optic nerve and cause vision loss ... for optic nerve damage. Researchers have implicated a ...
... the human gut and their impact on human health and ... research today. To address the most recent advances in this ... the world will come together at the Gut Microbiota for ... 9, 2014. The meeting is hosted by the Gut Microbiota ...
Cached Biology News:Landmark egg production study reveals reduction in environmental impact over past 50 years 2Landmark egg production study reveals reduction in environmental impact over past 50 years 3Researchers discover potential drug targets for early onset glaucoma 2Researchers discover potential drug targets for early onset glaucoma 3Attend the Gut Microbiota for Health World Summit 2014 2
(Date:1/15/2014)... January 15, 2014 Look inside the ... items for the lab, from fluid handling to instruments ... to ship when you order. , Preferred Solutions ... , from the L/S® model for precise flow control ...
(Date:1/15/2014)... This webinar will focus on EMA ... assessment in biosimilars. , Regulatory frameworks are evolving many ... however the complex nature of biopharmaceuticals makes the demonstration ... extremely challenging. Based on the specific aspects of biosimilar ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 The Microcompetition with ... major disease. One of these latent viruses is the Epstein ... arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory disease ... a study found that RA patients have high concentrations of ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched Sound ... Patients listen to sound therapy that is tailor-made for ... to months, their tinnitus volume decreases. , AudioNotch has previously ... Notched White Noise. Now, AudioNotch is pleased to announce to ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3
... for a moment that Silicon Graphics Inc. (better ... days before its Altix 3000 family of servers and superclusters ... SGI rolled out the latest version of its popular ... the Mountain View-based company, whose only manufacturing facility is in ...
... Internet programming? Is tech still an exciting space to work ... with computers was an introductory programming class in 1979 using ... fledgling Internet when I started college in 1985. There have ... programming and the business of information technology as interesting and ...
... giant Eli Lilly & Company recently expressed concern to ... HIPAA privacy rule may impede clinical research trials. , ... and approve thousands of patient authorizations for use and ... Crosley, chief privacy officer of Indianapolis-based Eli Lilly. ...
Cached Biology Technology:SGI, Introduces Powerful High End Visualization Tools 2SGI, Introduces Powerful High End Visualization Tools 3Interview: Billpoint Founder Jason May on eBay, Open Source 2Interview: Billpoint Founder Jason May on eBay, Open Source 3Interview: Billpoint Founder Jason May on eBay, Open Source 4
...
... T4 DNA Ligase catalyzes the formation ... ATP between double-stranded DNAs with 3' hydroxyl ... DNA Ligase buffer optimizes ligation which can ... nucleic acids are not substrates for this ...
Bovine Renal Artery Smooth Muscle Cells (BRASMC) (>500,000 cells)...
... The Finnpipette BioControl is a ... technology. A complete liquid handling system ... twelve interchangeable tip cone modules. All ... tip cone modules fit one handle. ...
Biology Products: