Navigation Links
UF scientists discover new explanation for controversial old patient-care technique

GAINESVILLE, Fla. You might not know what it's called, but if you've had general anesthesia before surgery, especially after an accident, it is likely you have received Sellick's maneuver. That's when fingers are pressed against a patient's throat to prevent regurgitation and spilling of stomach contents into the airway and lungs while anesthesia is being administered.

Such regurgitation could result in serious lung damage and even death.

The maneuver is a longstanding practice, first described in 1961 by British physician Brian Sellick. Performed dozens of times a day in hospitals, the procedure is accepted as "standard of care" and is a basic skill taught in all anesthesiology training programs. Anesthesiologists estimate conservatively that more than 100,000 people a year undergo the procedure.

But recently some physicians have begun to question the technique in the wake of a study challenging its effectiveness and ease of execution. And some have stopped using it altogether.

Now, researchers from University of Florida College of Medicine have used magnetic resonance imaging of the neck region to show that the maneuver works and that doubts about its effectiveness are based on a misunderstanding of what physical changes happen in the neck during the procedure.

"Sellick was right that the maneuver works but he was a bit off on the anatomy," said UF anesthesiologist Mark J. Rice, M.D., who led the study now online and to be featured on the cover of the November edition of the journal Anesthesia & Analgesia. The journal will also include two editorials on the controversial topic side by side with the UF paper, which has been selected by the editorial board as this month's graduate medical education article for November.

Also called cricoid pressure, the eponymous maneuver has for decades been described as the pinching of the esophagus between the cricoid a ring of cartilage that surrounds the trachea and the neck vertebrae.

It is most often used in accident victims whose stomachs might not be empty before surgery, or in patients who have bowel obstructions or slowed emptying of the stomach because of certain drugs or medical conditions.

Some doctors say that the procedure is hard to get right, and that not applying enough pressure and at a proper angle would cancel out any benefit.

A 2003 paper further cast strong doubt on the procedure's effectiveness with a finding that in 90 percent of cases, the esophagus moves to the side during the procedure. It is generally thought that the procedure is effective only if done at the midline of the neck. So researchers concluded that such movement of the esophagus means the maneuver can't effectively prevent regurgitation.

The UF researchers used open MRI imaging of the neck while the procedure was administered to volunteers. That allowed the person performing the technique to do so unimpeded, and increased the chance of reproducing how the procedure is carried out in a clinical setting.

It turns out, the imaging studies show, that the esophagus does not exist at that point in the neck where the procedure is done. Instead, it is a structure called the hypopharynx above the esophagus that gets pinched between the cricoid and the bones of the neck. The esophagus exists only lower down, near the shoulders. So movement of the esophagus doesn't affect the procedure since it is not involved, Rice and co-authors Lori Deitte, M.D., Anthony Mancuso, M.D., Nikolaus Gravenstein, M.D., Charles Gibbs, M.D., and Timothy Morey, M.D. found.

"This is a major error that's been in the literature for 50 years," said Rice, who is chief of liver transplantation in UF's department of anesthesiology.

As for the sideways movement, the study showed that the hypopharynx and cricoid structures move together, so effective compression is achieved even if it is pushed to the side in the process.

"It turns out it doesn't matter," Rice said.

The new findings serve to reassure doctors that the procedure works, and that they don't have to do it "perfectly" for it to be effective.

"Astonishingly enough, our previous assumptions are totally wrong," said professor Scott Springman, M.D., director of ambulatory anesthesia at the University of Wisconsin-Madison. "Now I can explain to my residents more accurately why we're doing it. I will use it in more situations than I would if I still had grave doubts about its efficacy."

Although the study doesn't prove directly that Sellick's maneuver prevents regurgitation, that is reasonably inferred from the images.

"Because of Dr. Rice's study, Sellick's maneuver has again been shown to have anatomic efficacy, despite it occurring in a way that is different from the classic description," Springman said. "It also shows us that previous assumptions are not always correct, and that new technology can help us refine our hypotheses."


Contact: Czerne M. Reid
University of Florida

Related biology news :

1. UF receives $12.2 million to establish national network of scientists
2. Caltech scientists create robot surrogate for blind persons in testing visual prostheses
3. Time in a bottle: Scientists watch evolution unfold
4. Scientists demonstrate link between genetic defect and brain changes in schizophrenia
5. Scientists remove amyloid plaques from brains of live animals with Alzheimers disease
6. UNC scientists win $1.6 million stimulus award to accelerate decoding of human genome
7. Scientists urge EPA to adopt systems thinking
8. Scientists identify common HPV genotypes in northern India, encourage vaccination
9. Scientists take step toward simple and portable tuberculosis tests for developing world
10. Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency
11. MDC scientists show how hematopoietic stem cell development is regulated
Post Your Comments:
(Date:10/29/2015)... YORK , Oct. 29, 2015 ... technology, announced a partnership with 2XU, a global ... to deliver a smart hat with advanced bio-sensing ... and other athletes to monitor key biometrics to ... the strategic partnership, the two companies will bring together ...
(Date:10/27/2015)... October 27, 2015 Munich, ... Gaze Mapping technology (ASGM) automatically maps data from mobile ... Glasses , so that they can be quantitatively ... Munich, Germany , October 28-29, 2015. ... data from mobile eye tracking videos created with ...
(Date:10/26/2015)... 26, 2015 ... adds Biometrics Market Shares, Strategies ... well as Emerging Biometrics Technologies: Global ... its collection of IT and Telecommunications ... --> . ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... of a new, Good Manufacturing Practice (GMP) 10000 in the Santiago Marriott. The ... available, and is operated by a world-class team of qualified medical researchers and ...
(Date:11/30/2015)... December 1, 2015 Partnership includes an ... for the u niversity , s ... treatment s cale - up ...   Africa , where licensees based anywhere in the world ... SDN technology. --> Africa , where licensees based anywhere in ...
(Date:11/30/2015)... , Nov. 30, 2015 Spherix ... company committed to the fostering and monetization of ... current and prospective initiatives designed to create shareholder ... Executive Officer of Spherix. "Based on published reports, ... licensees exceeds $50 billion and Spherix will seek ...
(Date:11/30/2015)... 30, 2015 TapImmune, Inc. ... of innovative peptide and gene-based immunotherapeutics and vaccines for ... it will be presenting at the 8 th ... at 2.30 PM PT. Dr. John N. Bonfiglio ... be giving the presentation and will join TapImmune management ...
Breaking Biology Technology: