Navigation Links
UF scientist tapped by Howard Hughes Medical Institute to pursue 'best ideas'
Date:3/26/2009

ived his master's degree in biological anthropology at Kent State University and his doctoral degree in developmental biology at University College London. Cohn is currently an associate professor in the biology department of the College of Liberal Arts and Sciences and the anatomy and cell biology department in the College of Medicine.

His findings have led to new levels of understanding of evolutionary processes and shed light on human problems such as birth defects.

"I realized that if I wanted to understand how animal form changes during evolution, such as how the skeleton evolved or how snakes lost their legs, I had to understand development, because that's when the genetic blueprint for the body is being executed," Cohn said.

He began by studying chick embryos, a classic scientific model of limb development. At University College London, he discovered that the embryonic master switch for limb formation was a multifunctional protein called fibroblast growth factor. The finding, published in the journal Cell, was later proven true for other animals, including people.

After finding the trigger, Cohn set out to find what determines the precise positioning of limbs, such as hands on the ends of arms at the shoulders, and feet on the ends of legs protruding from the trunk.

His research led him to the Hox family of genes, which direct the formation of body structures in organisms ranging from worms to people. His work showing that Hox9 genes determine where limbs develop along the trunk was published in the journal Nature in 1997. He went on to discover the molecular basis for loss of limbs during snake evolution and the role of Hox genes in the origin of jaws findings that were published in Nature in 1999 and 2002.

Since arriving at UF in 2003, Cohn's group has discovered the evolutionary origin of the genetic program for fin development, shown how this program was modified to form fingers and toes
'/>"/>

Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Whitehead member Peter Reddien named HHMI Early Career Scientist
2. New species of spiders discovered by UBC scientist in Papua New Guinea
3. Stanford scientists find new solutions for the arsenic-poisoning crisis in Asia
4. Queens scientists find new way to battle MRSA
5. Smithsonian scientist warns that palm oil development may threaten Amazon
6. LabRoots Launches Social Networking Site for Scientists & Engineers
7. Scientists find climate change to have paradoxical effects in coastal wetlands
8. Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death
9. Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants
10. Scripps research scientists watch as individual alpha-synuclein proteins change shape
11. Gladstone scientists reveal key enzyme in fat absorption
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 16, 2014  Automation is fundamentally transforming the ... than at international borders. Over the past decade, ... allowed veteran travelers to self process through border ... Kiosks at an increasing number of airports, seaports, ... According to Maxine Most , Principal ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has ... in India 2015-2019" report to their offering. ... this market is the adoption of multimodal biometric ... characteristic of an individual for verification and identification ...
(Date:12/10/2014)... Dec. 8, 2014 You,ve been here before: you ... can,t remember your password, site key or the answer to ... first grade teacher? Today, Hoyos Labs ... app that will finally put an end to the frustration ... TM . 1U leverages a user,s smartphone to acquire ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... Bristol is developing a revolutionary new test to detect breast ... be effective for women of all ages; given that breast ... of 35-55 in Europe, the test could have a dramatic ... The test, which utilises an innovative radar system, will enable ...
... ago, as the last ice age was beginning to wane, often ... in a new study led by University of Washington researchers, an ... dipstick to show that a key section of the West Antarctic ... thought it did. That means it couldn't have contributed as much ...
... University of,Jerusalem have succeeded in discovering and isolating ... structural and qualitative,characteristics that could have consequences for ... cells.,In addition to being obtained from plant tissue, ... quantities as a recombinant protein in,bacteria, making it ...
Cached Biology News:New Breast Cancer Test Could Save Lives 2Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed 2Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed 3The death of a very special chimpanzee 2
(Date:12/24/2014)...   BioLife Solutions , Inc. (NASDAQ: ... proprietary clinical grade hypothermic storage and ... products for cells and tissues  ("BioLife" or the ... Annual Meeting of Stockholders on May 4, 2015 (the ... the Annual Meeting represents a change of more than ...
(Date:12/24/2014)... 2014 SoundConnect’s ... to introduce cutting edge communication technology, provide ... of platform upgrades. This webinar series demonstrates ... in their quest to leverage web conferencing’s ... to SoundConnect’s Marketing Manager, Seanna Baumgartner, “Our ...
(Date:12/24/2014)... Nashville Fertility Center announced that ... the American Society for Reproductive Medicine (ASRM), a leading ... reproductive medicine. In his new role as treasurer, ... board and will have a voice in furthering the ... supported ASRM since 1984 when he joined while conducting ...
(Date:12/24/2014)... AUSTIN, Texas , Dec. 23, 2014 /PRNewswire/ ... solutions company focused on gynecologic disease, announced today ... W. Schuler , Birchview Fund LLC and several ... million of unregistered shares of Vermillion,s common stock ... common stock in a private placement.  ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5
... 20, 2011 , Daval International ... randomised, placebo-controlled, double blind Phase II,Study, Treating Patients ... Sclerosis (SPMS). Standard clinical,measures and assessment scores recorded ... biomarkers will be used to investigate safety,efficacy and ...
... WAYNE, Pa. and PETACH TIKVA, Israel, July 20, 2011 ... developing Detect-Ready® tests designed to increase the speed and ... diagnostics distributor Eldan, a part on the Neopharm Group, ... agreement for distribution of MDI,s Detect-Ready MRSA Panel in ...
... Institute have developed a new method to harvest energy ... creation of self-powered microsensors for more accurate and cost-efficient ... the researchers investigated how the flow of water over ... amounts of electricity. The research team demonstrated the creation ...
Cached Biology Technology:Daval International Announces Completion of Phase II Trial for the Treatment of Bladder Dysfunction With AIMSPRO® in Secondary Progressive Multiple Sclerosis 2Daval International Announces Completion of Phase II Trial for the Treatment of Bladder Dysfunction With AIMSPRO® in Secondary Progressive Multiple Sclerosis 3Molecular Detection Inc. and Eldan Electronic Instruments Announce Distribution Agreement for Detect-Ready® MRSA Panel in Israel 2Molecular Detection Inc. and Eldan Electronic Instruments Announce Distribution Agreement for Detect-Ready® MRSA Panel in Israel 3Molecular Detection Inc. and Eldan Electronic Instruments Announce Distribution Agreement for Detect-Ready® MRSA Panel in Israel 4New graphene discovery boosts oil exploration efforts, could enable self-powered microsensors 2New graphene discovery boosts oil exploration efforts, could enable self-powered microsensors 3