Navigation Links
UD leads $5.3-million research project on rice epigenetics
Date:9/10/2007

Using a novel deep sequencing technology that can in one fell swoop decode 50 million sequences representing well over a billion bases of DNA, a research team led by University of Delaware scientists is working to unmask where, why and how certain genes are switched on or off in rice--a crop vital to the world's food supply.

The goal of the four-year project, which is supported by a $5.3-million grant from the National Science Foundation (NSF), is to advance scientific understanding of the rice epigenome--the series of biochemical modifications of the rice DNA that can toggle a gene on or, conversely, silence it. Ultimately, the research may lead to the development of hardier strains of rice, as well as shed light on similar mechanisms at work in corn and other important cereal grains that are closely related to rice.

Blake Meyers, associate professor of plant and soil sciences at UD, is the principal investigator on the project, which also involves Guo-Liang Wang, a rice biologist from Ohio State University; Steven Jacobsen, an expert in epigenetics, and computer scientist Matteo Pellegrini, both from the University of California at Los Angeles; and Yulin Jia, a plant pathologist at the U.S. Department of Agriculture's Dale Bumpers National Rice Research Center in Stuttgart, Ark.

The effort builds on Meyers' previous awards from the NSF Plant Genome Research Program, as well as ongoing investigations of small RNAs--short lengths of ribonucleic acids that act as gene regulators--performed in collaboration with Pamela Green, the Crawford H. Greenewalt Endowed Chair in Plant Molecular Biology at UD, whose lab is next door to Meyers' in the Delaware Biotechnology Institute. These projects have now propelled the research in a new direction, to new frontiers in the field of epigenetics.

Epigenetics refers to a heritable change that is not a result of a change in DNA sequence, but rather a chemical modification of nuc
'/>"/>

Contact: Tracey Bryant
tbryant@udel.edu
302-831-8185
University of Delaware
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
2. Ants Genetic Engineering Leads To Species Interdependency
3. Study of genomic DNA leads to new advances in cancer diagnostics
4. Combination therapy leads to partial recovery from spinal cord injury in rats
5. Chemical guidance of T cells leads to immunologic memory and long-term immunity
6. Basic research leads to a novel cancer therapy
7. Less antibiotic use in food animals leads to less drug resistance in people, study shows
8. MBL leads effort to update E. coli genome
9. With cochlear implants, earlier use leads to better speech
10. Pest control research leads to pain control discovery
11. UT Southwestern researchers find gene mutation that leads to broken hearts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... production from shale rock has increased by more ... do not fully understand the industry,s effects on ... the journal Frontiers in Ecology and the ... vastly outpace scientific examination, a team of eight ... Princeton University, concluded that determining the environmental impact ...
(Date:7/31/2014)... A first-of-its-kind study of bigeye tuna movements in ... of the Large Pelagics Research Center at the University ... fish cover a wide geographical range with pronounced north-south ... they favor a high-use area off Cape Hatteras southwest ... used a new approach to study one of the ...
(Date:7/31/2014)... genes to the earliest common ancestor of butterflies ... an extensive "Tree of Lepidoptera" in the first ... , Among the study,s more surprising findings: Butterflies ... to large ones, which completely changes scientists, understanding ... that some insects once classified as moths are ...
Breaking Biology News(10 mins):'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 2'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 3Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
... Without aggressive action to reduce soot emissions, the time ... be significantly accelerated in order to achieve international climate ... December,s Copenhagen Accord, according to " Assessing the climatic ... online June 21 in the Proceedings of the National ...
... product is organic, it,s also environmentally friendly. ... organic pesticides can have a higher environmental impact ... require larger doses. Environmental sciences professor Rebecca ... effectiveness and environmental impact of organic pesticides to ...
... freshwater fishes has created a great home for parasites, according ... . The study provides a lens into the evolutionary world ... probably has the best studied freshwater fish parasites in the ... more species of flukes in a few fishes from the ...
Cached Biology News:Aggressive action to reduce soot emissions needed to meet climate change goals 2Aggressive action to reduce soot emissions needed to meet climate change goals 3Organic pesticides not always 'greener' choice, study finds 2Adaptation is (not) in the eye of the beholder 2
(Date:7/31/2014)... 31, 2014 Food and natural ... searching for food alternatives that offer variety, as ... food ingredient market has numerous players operating in ... Vital Force Technology (VFT). VFT is a ... energetic patterns, all tested to produce stable, effective ...
(Date:7/31/2014)... good reason people over 60 are not donor candidates ... weakens with time, making the elderly prone to life-threatening ... research team now has discovered a reason why. , ... inability of blood-forming cells to maintain blood production over ... defects that could be restored for rejuvenation therapies," said ...
(Date:7/31/2014)... BLOOMINGTON, Ind. -- Chemists at Indiana University Bloomington ... in bricks-and-mortar fashion, a development with potential value ... as field-effect transistors and photovoltaic cells. , Their ... 3D Crystalline Solids and 2D Self-Assembled Crystals," has ... a journal of the Royal Society of Chemistry. ...
(Date:7/31/2014)... Graphite Metallizing Corporation announces GRAPHALLOY® ... These bearings are uniquely suited to prevent loss of ... of the high temperatures . , Recently, a ... design engineers at Graphite Metallizing to overcome problems with ... manufacturing operation, pans containing blocks of powder mixture are ...
Breaking Biology Technology:Functional Ingredient Manufacturer – Vital Force Technology Infuses Raw Materials & Ingredients with Subtle Energy Formula 2Key to aging immune system is discovered 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 3Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3
... a private,biotechnology company and leading developer of clean ... Singapore,Pte. Ltd. (CLS). CLS is the company,s first ... the company,s research and development operations in the,U.S. ... business in,both the innovator and generics markets. ...
... Inc. (Amex: PLX ), announced today the pricing ... common stock at a,public offering price of $5.00 per ... underwriters to purchase up to 1,500,000 additional shares of,common ... Bank is acting as sole book-running manager for this,offering. ...
... Inc. (Nasdaq: HGSI ) today announced that it ... for the quarter ended,September 30, 2007. These results are ... (Logo: http://www.newscom.com/cgi-bin/prnh/20010612/HGSLOGO ) The conference call will ... Thursday, November 1, 2007, at 11:00 am Eastern Time. ...
Cached Biology Technology:Codexis Opens Singapore Laboratory 2Protalix BioTherapeutics Announces Pricing of Public Offering of Common Stock 2Human Genome Sciences To Sponsor Conference Call To Discuss Third Quarter 2007 Financial Results 2
UGT1A7 (E-15)...
Chicken Aortic Smooth Muscle Cells (CAOSMC) (>500,000 cells)...
... Hot Start Taq ... activity before the onset ... nonspecific amplification and primer-dimer ... is raised, the antibody ...
... UV irradiation and antimicrobial stainless steel to ... Quickly inactivate DNA between experiments with ... with antimicrobial coated stainless steel ... built-in 30-minute timer UVP's Sterilizing ...
Biology Products: