Navigation Links
UCSF unveils model for implantable artificial kidney to replace dialysis
Date:9/2/2010

rtension.

Yet transplants are difficult to obtain: a mere 17,000 donated kidneys were available for transplant last year, while the number of patients on the transplant waiting list currently exceeds 85,000, according to the Organ Procurement ant Transplant Network.

Roughly 350,000 patients are reliant on kidney dialysis, Roy explained, which comes at a tremendous cost. The Medicare system alone spends $25 billion on treatments for kidney failure more than 6 percent of the total budget while the disease affects only 1 percent of Medicare recipients, he said. That cost includes almost $75,000 per patient each year for dialysis, according to the U.S. Renal Data System.

Dialysis also takes a human toll. A typical dialysis schedule is three sessions per week, for 3 to 5 hours per session, in which blood is pumped through an external circuit for filtration. This is exhausting for patients and only replaces 13 percent of kidney function, Roy said. As a result, only 35 percent of patients survive for more than 5 years.

With the limited supply of donors, that means thousands of patients die each year waiting for a kidney.

The implantable device aims to eradicate that problem. The two-stage system uses a hemofilter to remove toxins from the blood, while applying recent advances in tissue engineering to grow renal tubule cells to provide other biological functions of a healthy kidney. The process relies on the body's blood pressure to perform filtration without needing pumps or an electrical power supply.

The project exemplifies the many efforts under way at UCSF to build collaborations across scientific disciplines that accelerate the translation of academic research into real solutions for patients, according to Mary Anne Koda-Kimble, PharmD, dean of the UCSF School of Pharmacy.

"This is a perfect example of the work we are doing at UCSF to address some of the most critical medical issues of our time, both
'/>"/>

Contact: Kristen Bole
kristen.bole@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. NPL unveils quantitative means of monitoring ultrasonic cleaning systems
2. McMaster study unveils lifeline for antibiotic of last resort
3. GestureTek Unveils The CUBE V3 Portable, Plug and Play Interactive Projection Display System for Advertising and Exhibits
4. MSU researcher unveils new approach to treat lower back pain
5. GestureTek Unveils The CUBE V3 Portable, Plug and Play Interactive Projection Display System for Advertising and Exhibits
6. HAMILTON Unveils ARC Sensor Technology
7. Largest ever Alzheimers genome study unveils dementia mysteries
8. Uniloc Unveils Industry-First Authentication Technology for Comprehensive Protection of Critical Infrastructure
9. Uniloc Unveils Industry-First Authentication Technology for Comprehensive Protection of Critical Infrastructure
10. NPL unveils new equipment to make cancer treatment safer
11. Promptu Unveils High Accuracy Voice-to-Text Dictation for Mobile Phones at CTIA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... of the fish world, are the ideal animal in ... They,ve moved from the ocean into tens of thousands ... time changing their skeleton to adapt to the new ... of sticklebacks now have turned up one of the ... simple change in that gene,s regulation in a freshwater ...
(Date:9/17/2014)... From accessible and affordable health care to reproductive ... depend on the ability of people to identify ... openly and respectfully, and find the most defensible ... practices to support these societal conversations?, The Hastings ... of Bioethical Issues have teamed up to publish ...
(Date:9/17/2014)... started in 2000 as an EC-FP5 four-year project, delivering ... steady progress and successful participations in several EC projects, ... Observation Network project (EU BON), to increase the ... and to extend the general dissemination of the Fauna ... has applied its novel e-Publishing tools to prepare ...
Breaking Biology News(10 mins):Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3Why bioethics literacy matters 2Why bioethics literacy matters 3Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2
... to find a DNA-based test to determine the sex ... sturgeon genome contains trematode genes that didn,t originally belong ... causes a sexually transmitted disease in humans. Genetics ... found the parasite and pathogen genes while analyzing DNA ...
... have developed a rapid, high-throughput screening method for prevention ... Munkongdee et al, "Rapid diagnosis of α-thalassemia by melting ... The Journal of Molecular Diagnostics . α-Thalassemia ... in the production of a component of hemoglobin. ...
... A flyover of Belize,s thick jungles has revolutionized archaeology ... by one of the most-studied ancient civilizations -- the ... NASA-funded research project in April 2009 that collected the ... days. Aboard a Cessna 337, LiDAR (Light Detection ...
Cached Biology News:Lake sturgeon have genes from parasite, signs of human STD 2Space technology revolutionizes archaeology, understanding of Maya 2Space technology revolutionizes archaeology, understanding of Maya 3
(Date:9/18/2014)... MA (PRWEB) September 18, 2014 ... Molecule Sequencing (tSMS™) technology, announced today the closing ... of investment, led by Genomic Diagnostic Technologies, will ... and diagnostic applications. , Founded in March 2013 ... and Bioinformatics Analyst at Helicos BioSciences, SeqLL has ...
(Date:9/18/2014)... Artificial sweeteners, promoted as aids to weight loss and ... intolerance and metabolic disease; and they do it in ... of the gut microbiota the substantial population of ... of experiments in mice and humans, were published today ... Eran Elinav of the Weizmann Institute,s Immunology Department, who ...
(Date:9/18/2014)... The quest for the ultimate memory device for computing ... at The City College of New York led by ... exhibit both magnetic and ferroelectric properties. , Combining both ... can occur between them and for the devices that ... Combining these two properties in a single material, however, ...
(Date:9/18/2014)... September 18, 2014 September 24 marks ... MX. ASEA is the manufacturer of the world's first ... care product, RENU28. , The Mexico City event ... Duvan Botero, and ASEA Field Leader Shawn Catmull from ... PhD in Atomic/Medical Physics from the University of Utah ...
Breaking Biology Technology:SeqLL Closes Series-A Funding Round for Expansion of Single Molecule Sequencing 2Gut bacteria, artificial sweeteners and glucose intolerance 2Gut bacteria, artificial sweeteners and glucose intolerance 3Oxides discovered by CCNY team could advance memory devices 2Announcing the ASEA Mexico Grand Opening Tour Beginning September 18th 2
... , High-level expression of difficult heterologous proteins ... has created variants of the Epicurian Coli ... of strains, which contain extra copies of the E. ... for a high-level,expression of proteins that are difficult to ...
... primary libraries with new plasmid library construction,kits , ... Barry,Neiditch Alan Greener John C. Bauer ... II,pcmv-script and pAD-GAL4-2.1 XR library ... into Epicurian Coli ,XL10-Gold ...
... , , , ,Over 40% of Stratagenes GeneConnection cDNA ... estimated to be full-length clones , Jason Goncalves ... GeneConnection discovery cDNA clone collection YY ... many ,different human tissues and has identified thousands of ...
Cached Biology Technology:Codon Bias-Adjusted BL21 Derivatives for Protein Expression 2Codon Bias-Adjusted BL21 Derivatives for Protein Expression 3Codon Bias-Adjusted BL21 Derivatives for Protein Expression 4Codon Bias-Adjusted BL21 Derivatives for Protein Expression 5Codon Bias-Adjusted BL21 Derivatives for Protein Expression 6Codon Bias-Adjusted BL21 Derivatives for Protein Expression 7Generate High-Quality, Directional Plasmid cDNA Libraries 2Generate High-Quality, Directional Plasmid cDNA Libraries 3Generate High-Quality, Directional Plasmid cDNA Libraries 4Generate High-Quality, Directional Plasmid cDNA Libraries 5Generate High-Quality, Directional Plasmid cDNA Libraries 6Generate High-Quality, Directional Plasmid cDNA Libraries 7The GeneZoo or the GeneJungle? 2The GeneZoo or the GeneJungle? 3The GeneZoo or the GeneJungle? 4The GeneZoo or the GeneJungle? 5The GeneZoo or the GeneJungle? 6The GeneZoo or the GeneJungle? 7The GeneZoo or the GeneJungle? 8The GeneZoo or the GeneJungle? 9The GeneZoo or the GeneJungle? 10
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential Neurological liabilities of compound...
... Clean-up Maxi Kit provides a fast and ... SDS, Triton X-100 and other detergents ... chromatography using Norgens patented protein resin as ... of processing 0.25 - 8 mg of ...
... Proteolytic degradation is critical to the ... and regulatory proteins as important and ... metabolism, heat shock and stress response, ... receptors and ion channels, cell cycle ...
... for the identification of potential biomarkers in urine, ... diseases. Due to the fact that urine can ... an attractive alternative to blood plasma as a ... Urine Protein Concentration Micro Kit provides a fast ...
Biology Products: