Navigation Links
UCSF researchers identify virus behind mysterious parrot disease
Date:7/30/2008

si and Ganem labs. Together with veterinarians Susan Clubb, in the United States, and Ady Gancz in Israel, Kistler analyzed affected birds using UCSF's patented ViroChip technology.

The ViroChip, which DeRisi and Ganem developed, is a high-throughput screening technology that uses a DNA microarray to test viral samples. The team was able to recover virus sequence from a total of 16 diseased birds from two different continents. The complete genome sequence of one isolate was captured using ultra deep sequencing.

The virus they identified is highly divergent from all previously identified members of the Bornaviridae family and represents the first full-length bornavirus genome ever cloned directly from avian tissue. Analysis of the Avian Bornavirus genome revealed at least five distinct varieties.

PDD is a fatal disease that causes nervous system disorders in both domesticated and wild birds in the psittacine, or parrot, family worldwide. The disease has been found in 50 different species of parrots, as well as five other orders of birds, and is widely considered to be the greatest threat to captive breeding of birds in this family, the researchers said.

The disorder often leads to the birds' inability to swallow and digest food, with resulting wasting; many birds also suffer from neurologic symptoms such as imbalance and lack of coordination. Regardless of the clinical course the disease takes, it is often fatal.

Scientists have theorized for decades that a viral pathogen was the source of the disease, but until now, no one had been able to identify the likely culprit.

"This provides a very compelling lead in the long-standing search for a viral cause of PDD," Ganem said. "With the development of molecular clones and diagnostic tests for ABV, we can now begin to explore both the epidemiology of the virus and how it is linked to the disease state."


'/>"/>

Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... for sniffing the highly infectious bacteria C. diff ... been developed by a team at the University of ... has demonstrated that it is possible to identify the ... lead to rapid diagnosis of the condition., What is ... to identify different strains of the disease simply from ...
(Date:8/31/2014)... are not busy attacking us, germs go after each ... spell disaster for the infected microbes: Sometimes viruses actually ... say, expand its diet or better attack its own ... an immune system would robotically destroy anything it recognized ... University have now revealed that one variety of the ...
(Date:8/31/2014)... Nature Climate Change , suggests that if current trends ... the global targets for total greenhouse gas (GHG) emissions in ... think carefully about the food we choose and its environmental ... just one of a number of actions that need to ... is enough food for all. , As populations rise ...
Breaking Biology News(10 mins):Scientists develop 'electronic nose' for rapid detection of C. diff infection 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 3Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4
... of Defence (MINDEF) and the Nanyang Technological University (NTU) ... strengthen Singapore,s defence science and technology research and development ... by inking a Memorandum of Understanding (MOU) at the ... the setting up of the Temasek Research Fellowship and ...
... Pharmaceutical Scientists (AAPS) is a professional, scientific society ... government and other research institutes worldwide. Founded in ... the exchange of knowledge among scientists to enhance ... scientific programs, on-going education, information resources, opportunities for ...
... tropical butterfly that potentially makes it able to distinguish between ... from the University of Bristol, UK. The team ... detection of predators, in particular birds. The Blue Morpho ... America, are more famous for their amazing wing colouration and ...
Cached Biology News:MINDEF, NTU join hands to boost Singapore's defense R&D capabilities 2
(Date:8/30/2014)... The Global and China Electrical ... study on the current state of the Electrical ... The report provides a basic overview of the ... Global market analysis and Chinese domestic market analysis ... trends and competitive landscape of the market. A ...
(Date:8/29/2014)... According to a new market report published ... market was valued at USD 3,754.6 million in 2012 and ... 2019at a CAGR of 5.9% from 2013 to 2019. , ... is afflicted by bone and joint disorders, and this number ... has and will continue to increase the demand for orthobiologics. ...
(Date:8/29/2014)... Three Lawrence Livermore researchers have ... Production R&D Award for their research in ... sunlight. , Shared with collaborators from the National ... Nevada, Las Vegas (UNLV), the award recognizes the ... solar-hydrogen production and corrosion processes. , These models ...
(Date:8/28/2014)... SPIE Fellow Glenn Boreman, Professor and ... and Director of the Center for Optoelectronics and Optical ... and co-founder and Chairman of the Board of Plasmonics, ... Vice President of SPIE, the international society for optics ... recent election results at the Annual General Meeting of ...
Breaking Biology Technology:Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3Livermore Team Awarded for Hydrogen Production Research 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... A new, one-year, double-blind controlled clinical study shows that ... risk in postmenopausal women with type 2 diabetes [1] ... Peter J. Curtis, Ph.D., et al , funded by ... Ltd., Israel, and Barry Callebaut, the world,s leading manufacturer of ...
... polymers will offer unprecedented control over the final polymer structure ... study published last week in the prestigious journal Nature ... in Sydney and the University of Warwick in the UK ... a combination of segregation and templating a pair of ...
... integrated circuits are found in many applications, from large ... integration is due in part to the semiconductor industry,s ... for decades. However, while silicon-based circuits continue to ... Law the prediction that the number of transistors ...
Cached Biology Technology:New Findings of Daily Consumption of Soy Isoflavones and Cacao-Flavonoids in Diabetes Type 2 Patients 2New Findings of Daily Consumption of Soy Isoflavones and Cacao-Flavonoids in Diabetes Type 2 Patients 3Bio-inspired polymer synthesis enhances structure control 2Next-generation nanoelectronics: A decade of progress, coming advances 2Next-generation nanoelectronics: A decade of progress, coming advances 3
Request Info...
SHEEP ANTI BOVINE BETA-LACTOGLOBULIN A...
Rabbit polyclonal to Somatostatin 28 ( Abpromise for all tested applications). entrezGeneID: 6750 SwissProtID: P61278...
... an essential component of the COP9 signalosome ... cellular and developmental processes. The CSN complex ... (Ubl) conjugation pathway by mediating the deneddylation ... ligase complexes. The complex is also involved ...
Biology Products: