Navigation Links
UCSF report describes new model for neurodegeneration
Date:3/10/2011

A team of scientists at the University of California, San Francisco (UCSF) has developed a new model for how inherited genes contribute to a common but untreatable and incurable neurodegenerative disease. The disease, frontotemporal lobar degeneration, is the second most common cause of dementia before age 65, after Alzheimer's disease.

Based on experiments in worms and mice, the UCSF team's work explains in part why the brain deteriorates in frontotemporal lobar degeneration, which may have implications for the understanding of several neurodegenerative disorders, including Alzheimer's and Parkinson's, as well as different forms of cancer.

"If our findings hold up," said Aimee Kao, an assistant adjunct professor in the Department of Neurology at UCSF, "they may suggest a new way to think about how to treat neurodegenerative diseases." Kao is first author on the study, led by Cynthia Kenyon, PhD, a professor of biochemistry and biophysics at UCSF and director of UCSF's Larry L. Hillblom Center for the Biology of Aging.

Disease Caused By Loss of Neurons

Generally scientists have blamed the mental decline associated with neurodegenerative diseases on the loss of neurons associated with the accumulation of insoluble protein in the brain sticky plaques that interfere with and ultimately kill the brain's neurons.

In frontotemporal lobar degeneration, this loss of neurons happens in the frontal lobe the part of the brain involved in such higher mental functions as art appreciation and emotional empathy. People with this disease can suffer from progressive difficulties with language, undergo personality and behavioral changes, and usually die within a decade of diagnosis.

The new work suggests that the accumulation of insoluble protein may not be the only cause of cognitive decline in frontotemporal lobar degeneration. Another mechanism could involve how the body deals with injured neurons in the brain.
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Reportlinker Adds Global Biometric Forecast to 2012
2. Even in a crowd, you remain unique, UCLA life scientists report
3. Shellshock: New report lists 25 most endangered turtle species
4. Reportlinker Adds Global Bioinformatics Industry
5. Challenges for biofuels: New life cycle assessment report from Energy Biosciences Institute
6. Arctic fisheries catches 75 times higher than previous reports: UBC research
7. Pitt team grows arteries with most elastic protein reported, big step for living vascular grafts
8. Researchers report on the early development of anti-HIV neutralizing antibodies
9. Cell Transplantation reports a success in treating end-stage liver disease
10. GEN reports on biotech acquisition deals in 2010 that topped $1 billion
11. Comprehensive report on sudden oak death
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSF report describes new model for neurodegeneration
(Date:12/4/2014)... 3, 2014  Crossmatch™, a leading provider of ... DigitalPersona ® Pro Enterprise software and U.are.U ... throughout First Bank branch locations in ... and Virginia. First Bank, a progressive community ... North Carolina , selected the Crossmatch biometrics-based ...
(Date:11/21/2014)... 2014 According to a new ... (Video, RFID, Access Control, Intrusion Detection, Parking Management, Under ... Component Service Geography - Global Forecasts to 2020", published ... to be around $25 Billion in 2014 and is ... a CAGR of 8.69%. Browse 116 market ...
(Date:11/21/2014)... Wash. , Nov. 20, 2014 C-Labs ... for the Internet of Things (IoT), today announced the ... of chief operating officer. Previously a strategic advisor to ... finance, and operations. Mr. Traynor is based out of ... . He reports to Chris Muench , Chief ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... the most common primary brain tumor, new findings may ... A UCSF-led team of scientists has identified for ... cells underly a type of glioma called oligodendroglioma. ... therapy than other brain tumors such as glioblastoma multiforme. ...
... Aviv ― Environmentalists around the world agree ― plastic bags ... a Tel Aviv University researcher is developing new laboratory methods ... those that biodegrade and are even tougher than those made ... answer to the problem, Prof. Moshe Kol of Tel Aviv ...
... plants to biofuels is that the very same molecules that ... down. Now scientists at the U.S. Department of Energy,s (DOE) ... structural supports - their cell walls - are made, with ... more efficient biofuel production. In a paper to be ...
Cached Biology News:Cell of origin for brain tumors may predict response to therapy 2Cell of origin for brain tumors may predict response to therapy 3The sweetness of biodegradable plastics 2Scientists unravel more details of plant cell-wall construction 2
(Date:12/24/2014)... BOTHELL, Wash. , Dec. 24, 2014   ... a leading developer, manufacturer and marketer of proprietary clinical ... media and precision thermal shipping products ... announced that it will hold its 2015 Annual Meeting ... Because the expected date for the Annual ...
(Date:12/24/2014)... SoundConnect’s 2015 ... introduce cutting edge communication technology, provide continued ... platform upgrades. This webinar series demonstrates online ... their quest to leverage web conferencing’s most ... SoundConnect’s Marketing Manager, Seanna Baumgartner, “Our webinars ...
(Date:12/24/2014)... Nashville Fertility Center announced that Dr. ... American Society for Reproductive Medicine (ASRM), a leading professional ... medicine. In his new role as treasurer, Dr. ... and will have a voice in furthering the mission ... ASRM since 1984 when he joined while conducting fellowship ...
(Date:12/24/2014)... , Dec. 23, 2014 Vermillion, Inc. ... on gynecologic disease, announced today that investors including ... Birchview Fund LLC and several Vermillion directors have ... shares of Vermillion,s common stock and warrants to ... a private placement.  Under the ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5
... - Wisconsin manufacturers made $215 million in efficiency ... Wisconsin Manufacturers Extension Partnership (WMEP) during the organization's last ... is a state-supported, non-profit organization providing consulting services to ... was based on a survey of its clients. It ...
... - The Wisconsin Economic Summit served its purpose ... four summits that took place between 2000 and 2003 ... that are shaping the state's growth. But once those ... to do something about them, the Wisconsin Economic Summit ...
... conference on protecting the U.S. food supply from terrorism and ... until spring from its original November dates. , ,The ... 1-3 in downtown Milwaukee, with as many as 1,000 people ... David Duecker, who, with the Wisconsin Procurement Institute, is helping ...
Cached Biology Technology:Manufacturing group says efforts led to big improvements 2Forum builds on the work of the Wisconsin Economic Summit 2Forum builds on the work of the Wisconsin Economic Summit 3
prototype Nco I...
Request Info...
Agarose for baculovirus plaque assays which allow optimal growth of plated insect cells....
Includes USB cable, custom driver and one roll of thermal paper...
Biology Products: