Navigation Links
UCSB scientists show how certain vegetables combat cancer
Date:12/23/2008

(Santa Barbara, Calif.) Women should go for the broccoli when the relish tray comes around during holiday celebrations this season.

While it has been known for some time that eating cruciferous vegetables, such as broccoli, cauliflower, and cabbage, can help prevent breast cancer, the mechanism by which the active substances in these vegetables inhibit cell proliferation was unknown until now.

Scientists in the UC Santa Barbara laboratories of Leslie Wilson, professor of biochemistry and pharmacology, and Mary Ann Jordan, adjunct professor in the Department of Molecular, Cellular, and Developmental Biology, have shown how the healing power of these vegetables works at the cellular level. Their research is published in this month's journal Carcinogenesis.

"Breast cancer, the second leading cause of cancer deaths in women, can be protected against by eating cruciferous vegetables such as cabbage and near relatives of cabbage such as broccoli and cauliflower," said first author Olga Azarenko, who is a graduate student at UCSB. "These vegetables contain compounds called isothiocyanates which we believe to be responsible for the cancer-preventive and anti-carcinogenic activities in these vegetables. Broccoli and broccoli sprouts have the highest amount of the isothiocyanates.

"Our paper focuses on the anti-cancer activity of one of these compounds, called sulforaphane, or SFN," Azarenko added. "It has already been shown to reduce the incidence and rate of chemically induced mammary tumors in animals. It inhibits the growth of cultured human breast cancer cells, leading to cell death."

Azarenko made the surprising discovery that SFN inhibits the proliferation of human tumor cells by a mechanism similar to the way that the anticancer drugs taxol and vincristine inhibit cell division during mitosis. Mitosis is the process in which the duplicated DNA in the form of chromosomes is accurately dist
'/>"/>

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Hebrew University scientists reveal mechanism that triggers differentiation of embryo cells
2. Haag honored with Presidential Early Career Scientists Award
3. UC San Diego and Genentech scientists develop potentially disruptive antibody sequencing technology
4. Scientists study how asbestos fibers trigger cancer in human cells
5. CSHL scientists discover new way in which ubiquitin modifies transcriptional machinery
6. New World post-pandemic reforestation helped start Little Ice Age, say Stanford scientists
7. Scientists fool bacteria into killing themselves to survive
8. Scientists find link between inflamed gums and heart disease
9. Scientists create tough ceramic that mimics mother of pearl
10. Scientists film inner workings of the immune system
11. Rooted plants move mysteriously down greenways, scientists say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSB scientists show how certain vegetables combat cancer
(Date:8/19/2015)... Aug. 19, 2015  VOXX International Corporation (Nasdaq: ... entered into a Definitive Agreement to purchase the ... authentication market leader EyeLock through an acquiring entity.  ... a controlling interest in the acquiring entity. The ... of due diligence.  Expanding on its existing supply ...
(Date:8/12/2015)... Florida , August 12, 2015 ... pace of mobile payment innovation and advanced biometrics technology ... replace the way consumers rely on using their credit ... with reinventing the future for payment services led by ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ...
(Date:8/10/2015)... The latest 364 page report from ... the global border security market . Visiongain ... 2015. Now: Border security is hard to achieve ... business critical issue you need to know about - and ... analysis of how this will impact your company and the ...
Breaking Biology News(10 mins):VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 2VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 3VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 4VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... patient society representatives gathered in Valencia, Spain for the ... Osteoporosis Patient Societies. Osteoporosis is a widespread ... as many as one in two women and one ... International Osteoporosis Foundation (IOF) CEO Patrice McKenney stated, ...
... has awarded one of this year,s ERC Advanced Grants ... well-established research in the field of biosilicates with prize ... is professor at Mainz University,s Institute of Physiological Chemistry. ... and production of genetically engineered enzymes (silicateins) that allow ...
... March 17, 2011 (BRONX, NY) Researchers at ... discovered that members of an enzyme family found in humans ... role in regulating cell motility. Their findings suggest an entirely ... metastatic cancer. , David Sharp, Ph.D. , associate professor ...
Cached Biology News:Enzyme can steer cells or possibly stop them in their tracks 2
(Date:8/31/2015)...  US-Australian drug discovery company, Novogen Limited (ASX: ... comprehensive scientific review has identified high value opportunities ... unmet patient need. Novogen is moving as quickly ... to entering into Phase 1 clinical trials with ... Executive Officer, Iain Ross , said that ...
(Date:8/31/2015)... 31, 2015 LabStyle Innovations Corp. (OTCQB: ... today announced it recently closed a round of ... used to support the global rollout and initial ... cloud-based, diabetes management solution that includes novel software ... glucose monitoring device, and for working capital purposes. ...
(Date:8/31/2015)... , ... August 31, 2015 , ... ... the world's most successful food and beverage processors, equipment manufacturers and leaders in ... product inspection and industrial weighing and formulation for manufacturers of bakery and snacks; ...
(Date:8/30/2015)... , August 31, 2015 ... einer Frau   für chirurgische   Behandlung     ... 7-90   werden für eine   verheerende   ... Frauen behandeln und die Anzahl ausgebildeter Chirurgen in Kenia ... Astellas gab heute bekannt, dass  Action on Fistula  seit ...
Breaking Biology Technology:Novogen Announces The Outcome Of A Comprehensive Science Review 2Novogen Announces The Outcome Of A Comprehensive Science Review 3Novogen Announces The Outcome Of A Comprehensive Science Review 4Novogen Announces The Outcome Of A Comprehensive Science Review 5Novogen Announces The Outcome Of A Comprehensive Science Review 6LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 2LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 3LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 4METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 3Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 4Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 5
... NEW YORK, April 18, 2011 KellBenx, a biotechnology ... (NIPD) of genetic and inherited disorders, announced today that ... Medical Center to research a new blood test that ... pregnancy – or even before women become pregnant. Preterm ...
... no larger than viruseshave been constructed through a revolutionary ... Liu and their colleagues at Arizona State University,s Biodesign ... construct arbitrary, two and three-dimensional shapes, mimicking those commonly ... ultimately find their way into a wide array of ...
... Carmell Therapeutics, a company that manufactures novel blood plasma-based ... closed on a Series A financing it will use ... for early clinical validation for the Company,s first products. ... Light Capital Partners, a private investment firm that invests ...
Cached Biology Technology:KellBenx Secures Worldwide Agreement With Cedars-Sinai Medical Center for Biomarker Technology to Predict Premature Births 2New DNA nanoforms take shape 2New DNA nanoforms take shape 3New DNA nanoforms take shape 4Carmell Therapeutics Completes Series A Financing to Advance the Development of Novel Bioactive Plastics 2Carmell Therapeutics Completes Series A Financing to Advance the Development of Novel Bioactive Plastics 3
... GeneMarker software has been designed and ... with a biologist friendly genotyping analysis tool. ... several research groups into the software. Their ... accuracy, flexibility and low acquisition cost. ...
These stopping screens are for the biolistic PDS-1000 He and Hepta systems. Supplied as 500 screens....
... OLIGO is a multi-functional program ... oligonucleotides from a sequence file ... DNA sequencing, site-directed mutagenesis, and ... hybridization temperature and secondary structure ...
... a revolutionary new application for DNA ... novel interface, Expression makes complex computational ... Expression uses the very latest computing ... the way sequences are analysed. Features ...
Biology Products: