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UCSB researchers perform pioneering research on Type 2 diabetes

ower of systems biology; namely, how a network perspective combined with computational modeling can shed new light on biophysical circuits, such as this beta-cell glucose transport system," said co-author Frank Doyle. "It cannot be done by molecular biology alone, nor computational modeling alone; rather, it requires the uniquely interdisciplinary approach that is second-nature here at UCSB." Doyle is associate dean for research of the College of Engineering; director of UCSB's Institute for Collaborative Biotechnologies; professor of chemical engineering; and the Mellichamp Chair in Process Control.

"We are excited to bring our 20 years of expertise on Type 1 diabetes and systems biology methods to look at the networks responsible for the onset of Type 2 diabetes," said Doyle.

According to the American Diabetes Association, 8.3 percent of the U.S. population has diabetes. The disease can lead to nerve loss, blindness, and death.

The first author of the paper is Camilla Luni, who was a UCSB postdoctoral researcher at the time of the study, and is now with the University of Padova, in Italy. The research was funded by a grant from the U.S. Army Research Office to UCSB's Institute for Collaborative Biotechnologies, and a grant from the U.S. National Institutes of Health.


Contact: Gail Gallessich
University of California - Santa Barbara

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