Navigation Links
UCLA study shows man-made fat may limit damage to heart attack victims
Date:8/5/2011

FINDINGS: A man-made fat called Intralipid, which is currently used as a component of intravenous nutrition and to treat rare overdoses of local anesthetics, may also offer protection for patients suffering from heart attacks.

Current treatment for a heart attack focuses on limiting the duration of the ischemic period, when blood flow to tissues is reduced, and on subsequently opening arteries to reestablish normal coronary blood flow. It is well known that injury to the heart muscle can occur after oxygen and nutrients in the blood flow back to deprived cells, a phenomenon known as reperfusion injury, and scientists have been seeking ways to minimize such injury.

A UCLA preclinical study identified how Intralipid a fat emulsion made up of a combination of soy bean oil, egg phospholipids and glycerin that provides essential fatty acids can prevent extensive heart damage and help preserve heart function when used during the return of blood flow to the heart immediately following a heart attack.

IMPACT: This research shows that intralipid may help cell integrity and function when the body is under stress, such as during a heart attack, thus introducing a new way to significantly decrease damage to the heart muscle due to reperfusion injury or to prolong the tolerance of a tissue or an organ to lack of oxygen.

The findings may have implications for future therapies. The technique is not limited to the heart, researchers say, and could potentially be used for any ischemic organs suffering a blockage in blood flow or for organs used for transplant.


'/>"/>

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-0777
University of California - Los Angeles Health Sciences
Source:Eurekalert

Page: 1

Related biology news :

1. Long-term study shows effect of climate change on animal diversity
2. £2 million study to reveal workings of dementia genes
3. New study looks to define evangelicals and how they affect polling
4. CU-Boulder study suggests air quality regulations miss key pollutants
5. Researchers study acoustic communication in deep-sea fish
6. Study reveals homeowner perceptions in fire-prone areas
7. Researchers study how pistachios may improve heart health
8. Study: urban black bears live fast, die young
9. New study indicates link between weight gains during pregnancy and dieting history
10. Study reveals specific gene in adolescent men with delinquent peers
11. Sweat it out: UH study examines ability of sweat patches to monitor bone loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... DURHAM, N.C. -- When you accidentally touch a hot ... know the basic neural circuits involved in sensing and ... out the molecular players. , Duke researchers have made ... molecule involved in pain in worms, and have built ... Sept. 2 in Nature Communications , may help ...
(Date:9/1/2014)... quality in the U.S. has improved steadily in recent ... overall dietary quality remains poor and disparities continue to ... new study from Harvard School of Public Health (HSPH). ... date that the extensive efforts by many groups and ... payoff, but it also indicates that these efforts need ...
(Date:9/1/2014)... minutes after birth, every child in the U.S. undergoes ... of conditions, including sickle cell disease. Thousands of children ... meaning many suffer and die from the disease each ... halt to at least some of those deaths. ... working in the lab of George Whitesides, the Woodford ...
Breaking Biology News(10 mins):Surprising new role for calcium in sensing pain 2Surprising new role for calcium in sensing pain 3Quality of US diet shows modest improvement, but overall remains poor 2Quality of US diet shows modest improvement, but overall remains poor 3Faster, cheaper tests for sickle cell 2Faster, cheaper tests for sickle cell 3
... created to provide a haven for both protected species ... Gothenburg have analysed species living on the seabed (benthic ... marine areas require special protection., , "It,s not possible ... park. That,s why I,ve done what experienced mushroom pickers ...
... This release is available in German . ... the carbohydrates they produce through photosynthesis in the leaves. However, ... heart to help transport this vital fuel. Instead, they use ... with colleagues from the Carnegie Institution for Science in California, ...
... of 34 institutions in 15 countries contributing to the measurements ... network, InGOS. , The network focuses on providing accurate information ... for a more vigorous climate action. In order to ... of greenhouse gas emissions is essential and not only ...
Cached Biology News:Life on Kosterhavet's seabed analyzed 2Sugar pump in plants identified 2Sugar pump in plants identified 3DTU is participating in a European network on measurement of greenhouse gases 2
(Date:8/30/2014)... (PRWEB) August 31, 2014 The ... a professional and in-depth study on the current ... Global and China. , The report provides a ... and industry chain structure. Global market analysis and ... focus on history, developments, trends and competitive landscape ...
(Date:8/29/2014)... According to a new market report published ... market was valued at USD 3,754.6 million in 2012 and ... 2019at a CAGR of 5.9% from 2013 to 2019. , ... is afflicted by bone and joint disorders, and this number ... has and will continue to increase the demand for orthobiologics. ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 Three ... Energy's 2014 Hydrogen Production R&D Award ... by splitting water using sunlight. , Shared with ... and the University of Nevada, Las Vegas (UNLV), ... developing models of photoelectrochemical solar-hydrogen production and corrosion ...
(Date:8/28/2014)... SPIE Fellow Glenn Boreman, Professor and ... and Director of the Center for Optoelectronics and Optical ... and co-founder and Chairman of the Board of Plasmonics, ... Vice President of SPIE, the international society for optics ... recent election results at the Annual General Meeting of ...
Breaking Biology Technology:Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3Livermore Team Awarded for Hydrogen Production Research 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... deep underground carries no significant threat to human health, despite ... Researchers found that the risk of death from poisoning ... rocks is about one in 100 million far less ... from the University of Edinburgh studied historical data on deaths ...
... University-University of Oregon Center for Sustainable Materials Chemistry, born ... moving into a second phase under a new five-year, ... through its Centers of Chemical Innovation Program, will allow ... and development and boost efforts to translate basic-level discoveries ...
... The Albert and Mary Lasker Foundation, ... research, announced today the winners of the 2011 Lasker Awards ... Horwich for basic medical research, Tu Youyou for ... of Health for public service. The Lasker Awards – considered ...
Cached Biology Technology:Health fears over CO2 storage are unfounded, study shows 2Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 2Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 3Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 42011 Lasker Awards Honor Medical Research Pioneers 22011 Lasker Awards Honor Medical Research Pioneers 32011 Lasker Awards Honor Medical Research Pioneers 42011 Lasker Awards Honor Medical Research Pioneers 52011 Lasker Awards Honor Medical Research Pioneers 62011 Lasker Awards Honor Medical Research Pioneers 7
... SYBR Green II RNA gel ... gel stain that has bright fluorescence when ... gels, making it ideal for use with ... scanners or standard UV transilluminators. A 500 ...
... records analyzes and reports the data from any ... the a chart recorder. The final data is ... The end-point selection is automatic for Systolic, Mean, ... computed. The user is always in the position ...
... is taking automated patch clamping to a new ... to generate thousands of high quality data points ... in ion channel drug discovery and safety testing. ... afforded by conventional patch clamping can now be ...
... Reagents for the differentiation of mouse ... cell bodies exist in the midbrain, where ... nigra, the ventral tegmental area, and the ... rise to extensive forebrain dopamine innervation ( ...
Biology Products: