Navigation Links
UCLA study looks at why heart attacks cause so much more damage in late pregnancy
Date:7/2/2012

Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.

While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.

The research is published in the July edition of the peer-reviewed journal Basic Research in Cardiology.

"This very early study may help us identify and better understand the mechanisms involved in the higher risks of heart disease during pregnancy and may provide new opportunities to better treat pregnant women with cardiovascular complications and risk factors," said senior study author Dr. Mansoureh Eghbali, an assistant professor of anesthesiology at the David Geffen School of Medicine at UCLA.

For the study, researchers assessed heart differences after heart attacks among late-stage pregnant female rats and non-pregnant animals. They found that the pregnant animals' hearts demonstrated poor functional recovery, with only 10 percent restoration of heart function, compared with 80 percent restoration among the non-pregnant group. The pregnant animals also had a four-fold increase in damaged heart tissue over the non-pregnant group.

"We observed worse heart function and a greater area of damage in hearts from the late-pregnancy group, compared to the non-pregnant group," said first author Dr. Jingyuan Li, a postdoctoral fellow in the department of anesthesiol
'/>"/>

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Genes may play role in educational achievement, study finds
2. Researchers and communities at risk join forces in volcano study
3. Study identifies pathway to enhance usefulness of EGFR inhibitors in lung cancer treatment
4. Study offers new insights into the effects of stress on pregnancy
5. Recruitment by genotype for genetic research poses ethical challenges, study finds
6. Study provides first evidence of coevolution between invasive, native species
7. UCSB scientists compile first study of potential for tsunamis in northwestern California
8. New study demonstrates the role of urban greenery in CO2 exchange
9. UGA study reveals flu-fighting role for well-known immune component
10. UCLA biologists reveal potential fatal flaw in iconic sexual selection study
11. Disappearing grasslands: ASU scientists to study dramatic environmental change
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCLA study looks at why heart attacks cause so much more damage in late pregnancy
(Date:12/22/2014)... 22, 2014 Research and Markets ... addition of the "The Global Watermarking ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... overview of the global digital media watermarking ... and monitor piracy by securely and invisibly ...
(Date:12/19/2014)... , Dec. 18, 2014   LaunchKey , the ... the post-password and Internet of Things era, today announced ... The venture round was led by Metamorphic Ventures with ... Venture Partners, VegasTechFund, and others.  LaunchKey has raised $4 ... to expand its team and bring LaunchKey to market ...
(Date:12/17/2014)... 2014 Research and Markets ( ... "Global Chemical Sensor Market 2015-2019" report ... http://photos.prnewswire.com/prnh/20130307/600769 One major trend upcoming ... medical sensors in biomedical applications. Chemical sensors help ... correct diagnosis during surgical procedures. The Global Chemical ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... of atheist scientists are spiritual, according to new research from ... the study found that spirituality is a separate idea ... "spiritual atheist" scientists. The research will be published ... Through in-depth interviews with 275 natural and social ...
... has been shown to detect marine pollutants such as oil ... biosensor, published in Environmental Toxicology and Chemistry , reveal ... tracking of oil spills. The biosensor has been developed ... and was tested in the Elizabeth River and Yorktown Creek ...
... - 5 May 2011 - The use of animal ... advance our understanding of disease and to develop new ... psychiatric disorders, including autism spectrum disorders and schizophrenia. Individuals ... everyday functioning. Oxytocin and vasopressin are hormones that ...
Cached Biology News:More than 20 percent of atheist scientists are spiritual 2New biosensor modelled on the immune system can detect, track and guide the clean-up of oil spills 2Can one model the social deficits of autism and schizophrenia in animals? 2
(Date:12/24/2014)... New York (PRWEB) December 23, 2014 According ... the Long Island Affiliate of ITRA Global, the national office ... but steady recovery. This is evidenced by the third ... strong stock market. Low energy costs have held inflation ... The only negative is the housing market remaining soft. , ...
(Date:12/24/2014)... -- China Biologic Products, Inc. (NASDAQ: CBPO, "China ... plasma-based biopharmaceutical company in China ... Taibang Biological Products Co. Ltd., has received Good ... and Drug Administration (the "CFDA") for its new ... the Company,s public filings, the CFDA inspected this ...
(Date:12/24/2014)... PARIS and NEW YORK ... data from its open-label pilot study of mazindol in ... Design, Development and Therapy in December 2014 . ... of mazindol in children with attention deficit/hyperactivity disorder" ( ... 2014 Dec 1;8:2321-2332. eCollection 2014 ) ...
(Date:12/22/2014)... SAN DIEGO , Dec. 22, 2014 ... that the Decipher Prostate Cancer Classifier, a genomic test ... disease in node-negative, high-risk men managed by radical prostatectomy ... with radical prostatectomy is relatively uncommon, using tumor genomics ... form of metastatic disease is an important advance. The ...
Breaking Biology Technology:ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3
... , a Wisconsin company specializing in functional Magnetic ... honored with a Wisconsin Small Business Innovation Award ... a Phase I Small Business Innovation Research (SBIR) ... begin the development and validation of fMRI-based biomarkers ...
... up a pizza the other night. I ran into Doug ... the massive digital image library. Doug is now the ... digital pictures. , ,If, like me, youve found that by the ... moment for sharing has passed, then youll like ZoomAlbum. This ...
... today approved GE Healthcare's Lunar iDXA, a ... detect, diagnose and monitor treatment of osteoporosis, a disease ... fracture, more accurately and earlier in the disease process. ... composition and ascertain fat distribution. , ,In addition, ...
Cached Biology Technology:ZoomAlbum operates virtually 2ZoomAlbum operates virtually 3
Chicken Anti-Human DNA-directed RNA Polymerase II 7.6 Kd Polypeptide (POLR2L Polyclonal AntibodyOther Sub-Family: not assigned-Other Applications: ELISA, Western Blot...
...
The BD CBA Human Apoptosis Kit can be used to quantitatively measure,cleaved PARP, Bcl-2, and active Caspase-3 protein levels in a single sample. The,Kit performance has been optimized for analysis o...
BD Primaria 35 mm Cell Culture Dish with Easy-Grip design, surface-modified polystyrene for enhanced cell culture. (20/sp, 200/ca) Packaging: 20 / sleeve, 500 / case ...
Biology Products: