Navigation Links
UCLA stem cell scientists discover new airway stem cell
Date:6/27/2011

Researchers at UCLA have identified a new stem cell that participates in the repair of the large airways of the lungs, which play a vital role in protecting the body from infectious agents and toxins in the environment.

The airways protect the body by producing and clearing mucus from the airways. The mucus is largely produced by specialized mucus glands in the airway and the mechanisms of normal and excessive mucus production are not well understood. However, this newly discovered lung stem cell for the mucus glands will likely yield new insights into this critical process.

The study, by scientists with the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, represents the first time anyone has found the cell of origin for the many types of cells that make up the mucus glands and that can also repair the surface epithelium. The finding, the study states, is of "major importance to the field of lung regeneration."

"We're very excited that we found this population of cells because it will allow us to study mechanisms of diseases of the upper airway," said Dr. Brigitte Gomperts, an assistant professor of pediatrics and hematology/oncology and senior author of the study. "For example, there currently are no treatments for excess mucus production, which we see in cystic fibrosis, asthma and chronic obstructive pulmonary disease (COPD). But if we can understand the mechanisms of how these stem cells repair the mucus glands, then we may be able to find a way to put the brakes on the system and prevent mucus over production."

The study appears in the June 27, 2011 issue of the peer-reviewed journal Stem Cells.

Ahmed Hegab, a postdoctoral scholar in Gomperts lab and first author on the study, named the newly discovered cells sub-mucosal gland duct stem cells, because they are found in the ducts where the mucus is first secreted. Hegab and Gomperts had been looking for the lung stem c
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... and larger areas of sea ice melt in the summer ... it is thinner and more reduced. As the Arctic summers ... warming, because reduced sea ice in the Arctic will remove ... our results are representative, then sea ice plays a greater ... in future global CO2 budgets", says Dorte Haubjerg Sgaard, PhD ...
(Date:9/22/2014)... Boulder, CO, USA More than 7,000 geoscientists will ... papers at The Geological Society of America,s 126th Annual ... will cover such topics as the transportation of crude ... Mars. A dedicated field guide, Trials and Tribulations of ... in and around the Vancouver area. , A broad ...
(Date:9/21/2014)... Calif.) Mothers of children with autism are significantly less ... their pregnancies than the mothers of children who are ... Davis MIND Institute has found. , Low iron intake ... in the child if the mother was 35 or ... if she suffered from metabolic conditions such as obesity ...
Breaking Biology News(10 mins):Arctic sea ice helps remove CO2 from the atmosphere 2Geoscience topics in the spotlight -- Vancouver, BC 2Geoscience topics in the spotlight -- Vancouver, BC 3Geoscience topics in the spotlight -- Vancouver, BC 4Geoscience topics in the spotlight -- Vancouver, BC 5Mothers of children with autism less likely to have taken iron supplements 2
... has been awarded $6.27 million to develop an interactive ... efficient at home. The funding, which covers a two-year ... Advanced Research Projects Agency-Energy (ARPA-E), About $1.28 million in ... the California Energy Commission. The Stanford team will ...
... environmental impact of marine fisheries has caught the eye ... ,ecological risk assessment, (ERA) method have been adopted in ... Pacific, and by the international eco-labelling organisation the Marine ... led by Dr Tony Smith and Dr Alistair Hobday ...
... 150 years ago, he deliberately avoided the subject of the ... ,Creator, in the last paragraph of the book, led us ... matter. An international team, led by Juli Peret of the ... that the British naturalist did explain in other documents how ...
Cached Biology News:Stanford researchers awarded $6.27 million to study energy efficiency and human behavior 2World interest in Australian fishery impact test 2Charles Darwin really did have advanced ideas about the origin of life 2
(Date:9/23/2014)... NY (PRWEB) September 23, 2014 Marktech ... of deep ultra violet emitters in the 280 nm ... standard UV emitters which range from 280nm to 405nm. ... and water sanitation as well as curing. Mark Campito, ... line of special interest to manufacturers is that we ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 The ... a developer of cellular modems , platforms ... in the Startup category for the 2014 Tekne ... held at the Minneapolis Convention Center on Thursday, ... and individuals who have shown superior technology innovation ...
(Date:9/22/2014)... Pearl's Premium Ultra Low Maintenance Lawn Seed announced ... this week with the release of their Pearl's Premium, ... fact that it is time to plant now and ... As of the date 6/4/13, Pearl's Premium had well ... and the media including: The National Gardeners Assoc. ...
(Date:9/22/2014)... developed by researchers at the USC Viterbi School ... a 3-D microfluidic system quickly and cheaply by ... , Microfluidic systems are used in many fields ... small volumes of fluids for use in applications ... clinical diagnostic testing, and synthetic chemistry. Traditionally, microfluidic ...
Breaking Biology Technology:Marktech Introduces its New Line of Deep UV Emitters 2NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3Pearl's Premium Ultra Low Maintenance Lawn Seed Announces A Major Breakthrough In Drought Tolerant Grass Seed 2Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 2Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 3Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 4Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 5
... posts record quarterly revenues of $27.2 million, ... CRY ),a biomaterials, medical device and tissue processing ... of 2008 increased 18 percent to,$27.2 million compared ... 2007.,Excluding orthopaedic tissue processing revenues of $297,000 and ...
... Including Industrial ... ... Bioscience (Nasdaq:,PURE) today announced an agreement with DuraBan International ... DuraBan,s DuraClean(TM) brand., (Logo: http://www.newscom.com/cgi-bin/prnh/20060119/LATH060LOGO ), ...
... Ontario, July 31 TurboSonic,Technologies, Inc. (OTC Bulletin Board: ... industrial air pollution control technologies, today,announced that the company,s ... WallSt.net,s 3-Minute Press Show., The interview gives viewers ... company,s latest press release., To ...
Cached Biology Technology:CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 2CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 3CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 4CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 5CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 6CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 7CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 8CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 9CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 10CryoLife's Earnings Per Share Increased 180 Percent to $0.14 in Second Quarter of 2008 from $0.05 in Second Quarter of 2007 11PURE Bioscience Announces DuraBan International as Distributor of SDC-Based Disinfectant 2PURE Bioscience Announces DuraBan International as Distributor of SDC-Based Disinfectant 3PURE Bioscience Announces DuraBan International as Distributor of SDC-Based Disinfectant 4[video] Edward Spink, CEO of TurboSonic Technologies, Inc. Discusses Contract With Biofuel Producer in Exclusive Interview on WallSt.net's 3-Minute Press Show 2
D-biotin *50 mM aqueous solution* Secondary Detection Biotin–Avidin Detection Reagents Other...
Endothelin-converting enzyme 1 (EC 3.4.24.71) (ECE-1). [Source:Uniprot/SWISSPROT;Acc:P42892] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
X-Gal (5-Bromo-4-Chloro-3-Indoyl-beta -D-Galactopyranoside)...
...
Biology Products: