Navigation Links
UCLA researchers to study depression in breast cancer survivors
Date:11/6/2012

UCLA researchers received a five-year, $5 million grant from the National Cancer Institute that will fund a study seeking to uncover risk profiles of breast cancer survivors likely to suffer from depression.

UCLA will be teaming up with Kaiser Permanente, which will provide the 300 volunteers needed for the study by culling through electronic patient records to locate women who have been treated for breast cancer and don't have a history of depression.

Researchers believe that cancer and its treatment induce inflammation, which in turn leads to sleep disturbance and depression. Sleep disturbance occurs in more than half of breast cancer survivors, and is thought to contribute to the nearly four-fold elevated risk of depression in these women. Depression negatively impacts quality of life and increases risk of death, possibly due to increased chance of cancer recurrence.

Through the study, researchers hope to find out if certain sub-sets of breast cancer survivors are more at risk for depression by examining their DNA for potential biomarkers and genetic anomalies. If they can identify a risk profile, a study would be launched later to evaluate prevention measures, said Dr. Michael Irwin, a professor of psychiatry and biobehavioral sciences at the Cousins Center for Psychoneuroimmunology at the UCLA Semel Institute for Neuroscience and Human Behavior.

"Depression in breast cancer survivors is a huge problem. It often goes undiagnosed and is under treated," Irwin said. "If we can identify those breast cancer survivors at elevated risk for sleep disturbance and, therefore, depression, we can diagnose and treat it earlier with better outcomes. Additionally, if we can identify those at greatest risk, efforts can be implemented early to prevent the occurrence of depression in the first place. Because depression is so prevalent and difficult to treat in breast cancer survivors, prevention of depression will dramatically improve qual
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Princeton researchers identify unexpected bottleneck in the spread of herpes simplex virus
2. Iowa State, Ames Lab researchers find 3 unique cell-to-cell bonds
3. Researchers use blood testing to predict level of enzymes that facilitate disease progression
4. Researchers identify genetic basis of cardiac, craniofacial birth defects
5. Duke researchers engineer cartilage from pluripotent stem cells
6. NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer
7. Researchers decipher the mecanism of membrane fission
8. SDSU researchers to study Chinas national treasure
9. Exercise boosts satisfaction with life, researchers find
10. UC Davis researchers develop new drug delivery system for bladder cancer using nanoparticles
11. Far from random, evolution follows a predictable genetic pattern, Princeton researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... SAN JOSE, Calif. , Oct. 20, 2014 /PRNewswire/ ... with the United States Air Force Research Laboratory (AFRL), ... for Integrative Medicine (AzCIM) at the University of Arizona ... to receive research funding.  The AzCIM project,s goal is ... their ability to collect different volumes of sweat under ...
(Date:10/18/2014)... referred for evaluation of suspected genetic conditions, whole-exome ... percent, including detection of a number of rare ... according to a study appearing in JAMA ... with the American Society of Human Genetics annual ... coding regions of thousands of genes simultaneously using ...
(Date:10/17/2014)... To date, antidotes ... doctors are often limited to supportive therapy such as induced ... of drugs involved. So what can be done if a ... professor Jean-Christophe Leroux from the Institute of Pharmaceutical Sciences at ... "The task was to develop an agent that could eliminate ...
Breaking Biology News(10 mins):Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 2Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 3Whole-exome sequencing shows potential as diagnostic tool 2Emergency aid for overdoses 2Emergency aid for overdoses 3
... to honey bees, neuropeptides control brain activity and, hence, our ... of a honey bee will assist researchers in understanding the ... a million neurons in the brain of a honey bee ... of the period at the end of this sentence. The ...
... that controls the colour of apples ?a discovery that may ... in apple skin is the result of anthocyanins, the natural ... flowers and fruits," says the leader of the CSIRO Plant ... a very important part of fruit marketing," she says. "If ...
... half the animal species on the planet has been re-drawn ... four major groups of insects. , Scientists have ... beetles and more distantly related to bees and wasps, contrary ... in the special Honey Bee Genome issue of the journal ...
Cached Biology News:Scientists identify 36 genes, 100 neuropeptides in honey bee brains 2Found -- the apple gene for red 2New genetic analysis forces re-draw of insect family tree 2
(Date:10/20/2014)... Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced four new ... and provides a good start to Q4.  The orders are for ... and one in the Middle East . ... Peter Bruijns , President & CEO. "Total bidding activity and ... have been for any complete year since the company has tracked ...
(Date:10/20/2014)... 2014 OncLive® is ... Center at Thomas Jefferson University has joined its ... Strategic Alliance Partnership program, the Sidney Kimmel Cancer ... raise awareness of the Center’s cutting-edge research programs, ... Clinicians and other health care professionals from the ...
(Date:10/19/2014)... OCTOBER 20-22, 2014: The 9th Annual ... take place at the Congress Center Basel, ... now available at http://www.abim.ch . ... from all over the globe will exchange ... products and developments on the world market. ...
(Date:10/19/2014)... October 19, 2014 The Asia-Pacific Speech ... market in Asia-Pacific with analysis and forecast of revenue. ... in 2014 to $208 million by 2019, at a ... to 2019. , Browse through the TOC of the ... of the in-depth analysis provided. It also provides a ...
Breaking Biology Technology:Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
... , , , ... BioLife Solutions, Inc. (OTC Bulletin Board: BLFS), a leading ... and organs, today announced the launch of its BloodStor biopreservation ... for cryopreservation of umbilical cord blood stem cells, as well ...
... , , , FREDERICK, Md., Aug. ... Scientist Magazine,s 2009 Top 30 Best Places to Work ... those companies with the most positive work environment, dedicated management, and innovative ... Places to Work Industry award for biotech and pharmaceutical companies. ...
... , , , ... Aug. 28 Avid Bioservices, Inc., a leading provider of cGMP contract ... further strengthened its executive team with the appointments of Truc Le as ... These additions reflect Avid,s recent successes in expanding its customer base ...
Cached Biology Technology:BloodStor(TM) Stem Cell Biopreservation Media Platform Launched by BioLife Solutions 2BloodStor(TM) Stem Cell Biopreservation Media Platform Launched by BioLife Solutions 3SABiosciences Ranked 17th on the Best Places to Work Industry Award for Biotech and Pharmaceutical Companies 2Avid Bioservices Expands Executive Team as it Prepares for Continued Growth 2Avid Bioservices Expands Executive Team as it Prepares for Continued Growth 3Avid Bioservices Expands Executive Team as it Prepares for Continued Growth 4Avid Bioservices Expands Executive Team as it Prepares for Continued Growth 5
... a tetramethylrhodamine-conjugated jetSI-ENDO (excitation at ... nm), the powerful siRNA transfection ... to determine the transfection efficiency ... and trafficking of siRNAs. More ...
... movement counts, similar to an infrared beam break ... subjects at once, in two frames of reference, ... experimental group at once, and allow social interaction ... a variety of other spatial behavior situations, including ...
... a score of movement counts, similar to an ... up to 6 subjects at once, in two ... Can outpt a sync pulse to coordinate with ... animal location and timing information to control arena ...
... features of Tracker, plus software to note when ... of the arena, and trigger a penaltyThe Spatial ... built around a video camera, frame grabber, and ... fields at once and up to 6 moving ...
Biology Products: