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UCLA researchers engineer bacteria to turn carbon dioxide into liquid fuel
Date:12/10/2009

Global climate change has prompted efforts to drastically reduce emissions of carbon dioxide, a greenhouse gas produced by burning fossil fuels.

In a new approach, researchers from the UCLA Henry Samueli School of Engineering and Applied Science have genetically modified a cyanobacterium to consume carbon dioxide and produce the liquid fuel isobutanol, which holds great potential as a gasoline alternative. The reaction is powered directly by energy from sunlight, through photosynthesis.

The research appears in the Dec. 9 print edition of the journal Nature Biotechnology and is available online.

This new method has two advantages for the long-term, global-scale goal of achieving a cleaner and greener energy economy, the researchers say. First, it recycles carbon dioxide, reducing greenhouse gas emissions resulting from the burning of fossil fuels. Second, it uses solar energy to convert the carbon dioxide into a liquid fuel that can be used in the existing energy infrastructure, including in most automobiles.

While other alternatives to gasoline include deriving biofuels from plants or from algae, both of these processes require several intermediate steps before refinement into usable fuels.

"This new approach avoids the need for biomass deconstruction, either in the case of cellulosic biomass or algal biomass, which is a major economic barrier for biofuel production," said team leader James C. Liao, Chancellor's Professor of Chemical and Biomolecular Engineering at UCLA and associate director of the UCLADepartment of Energy Institute for Genomics and Proteomics. "Therefore, this is potentially much more efficient and less expensive than the current approach."

Using the cyanobacterium Synechoccus elongatus, researchers first genetically increased the quantity of the carbon dioxidefixing enzyme RuBisCO. Then they spliced genes from other microorganisms to engineer a strain that intakes carbon
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Contact: Matthew Chin
mchin@support.ucla.edu
310-206-0680
University of California - Los Angeles
Source:Eurekalert

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