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UCLA researchers develop system that finds prostate cancer spread earlier than conventional imaging
Date:9/22/2011

The tumor growth rate in this bone metastasis model is not uniform, ranging from no spread to large tumor lesions in the bone marrow cavity. The PSES imaging system correctly identified two out of nine animals in which the tumor did not grow. These results give researchers confidence that the PSES imaging system is functioning correctly in being able to seek out prostate cancer bone metastases in a specific and sensitive manner, Wu said.

"Taken together, this study demonstrated that the promising utility of a potent, androgen-independent and prostate cancer-specific expression system in directing gene-based molecular imaging in castration resistant prostate cancer, even in the context of androgen deprivation therapy," the study states.

Prostate cancer is the most common cancer for males in America and its spread to other organs is the major cause of mortality. This year alone, more than 217,000 American men will be diagnosed with the malignancy. Of those, more than 32,000 will die from their disease.


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Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles Health Sciences
Source:Eurekalert

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