Navigation Links
UCLA physicists control chemical reactions mechanically
Date:9/17/2010

ach it to a third place and affect another step in this chemical reaction."

Zocchi, Tseng and Wang studied the rate of the chemical reactions and reported in detail what happened to the steps of the reactions as they applied mechanical stress to the enzyme at different places.

"Standing on the shoulders of 50 years of structural studies of proteins, we looked beyond the structural description at the dynamics, specifically the question of what forces and applied where have what effect on the reaction rates," Zocchi said.

In a related second paper, Zocchi and his colleagues reached a surprising conclusion in solving a longstanding physics puzzle.

When one bends a straight tree branch or a straight rod by compressing it longitudinally, the branch or rod at first remains straight and does not bend until a certain critical force is exceeded. At the critical force, it does not bend a little it suddenly buckles and bends a lot.

"This phenomenon is well known to any child who has made bows from hazelnut bush branches, for example, which are typically quite straight. To string the bow, you have to press down on it hard to buckle it, but once it is bent, you need only a smaller force to keep it so," Zocchi said.

The UCLA physicists studied the elastic energy of their DNA molecular spring when it is sharply bent.

"Such a short double-stranded DNA molecule is somewhat similar to a rod, but the elasticity of DNA at this scale was not known," Zocchi said. "What is the force the DNA molecular spring is exerting on the enzyme? We have answered this question.

"We find there is a similar bifurcation with this DNA molecule. It goes from being bent smoothly to having a kink. When we bend this molecule, there is a critical force where there is a qualitative difference. The molecule is like the tree branch and the rod in this respect. If you're just a little below the threshold, the system has one
'/>"/>

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California -- Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Applied physicists create building blocks for a new class of optical circuits
2. CU physicists use ultra-fast lasers to open doors to new technologies unheard of just years ago
3. Digging deep into diamonds, applied physicists advance quantum science and technology
4. Rice physicists kill cancer with nanobubbles
5. Diamonds may be the ultimate MRI probe, say Quantum physicists
6. Louisiana Tech physicists highlight top 10 science stories of 2008
7. How do bacteria swim? Brown physicists explain
8. Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue
9. Improving crisis prediction, disaster control and damage reduction
10. Soyscreen: Sunscreen for fungus to expand biological control of crop pests
11. On organic coffee farm, complex interactions keep pests under control
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... critical and pertinent for practicing physicians and clinicians given ... The Journal, Disaster Medicine and Public Health Preparedness ... Public Health, to surround the public, medical professionals and ... , On October 17, the journal published ... was prepared by Dr. Eric Toner, internist and emergency ...
(Date:10/16/2014)... Institute of Marine Science have received a 3-year, ... identify the streams and wetlands most vulnerable to ... local governments and citizens conserve these important ecosystems. ... of tidal-marsh observations first gathered by VIMS scientists ... can today,s researchers accurately map the slow but ...
(Date:10/16/2014)... women experienced improvements in vaginal atrophy, with no ... after 12 weeks of daily 10 milligram (mg) ... supplement previously shown to help relieve certain menopause ... reported in a poster at the North American ... "These data documented improved vaginal epithelium, without significant ...
Breaking Biology News(10 mins):EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2
... 2012  The board of directors of Westlake Chemical Corporation (NYSE: ... 18.75 cents per share, an increase of over 150% from ... of 2012. The increased dividend will be payable on September 12, ... This is the 32nd successive quarterly dividend that Westlake ...
... the size of their poison glands to potential predators, finds ... Frontiers in Zoology . The brighter the colour, the ... different animals to warn potential predators that they are poisonous. ... which predators quickly learn to avoid. Paper wasps have conspicuous ...
... certain disease mechanisms, illness progression and response to new ... such as nematodes, fruit flies or zebra fish. ... of many individual animals to detect mutants worthy of ... system that uses artificial intelligence and cutting-edge image processing ...
Cached Biology News:Artificial intelligence helps detect subtle differences in mutant worms 2Artificial intelligence helps detect subtle differences in mutant worms 3Artificial intelligence helps detect subtle differences in mutant worms 4
(Date:10/20/2014)... Mapp Biopharmaceutical,s valiant effort to produce ... fight the Ebola outbreak will make the public ... of pharmaceuticals can be, according to Kalorama Information.  ... some may be taken aback by the three-month ... knowledge are well aware of the complex issues ...
(Date:10/20/2014)... Oct. 20, 2014 Asterias Biotherapeutics, Inc. ... has signed a Notice of Grant Award (NGA) ... effective October 1, 2014.  The NGA provides for ... the release of additional grant funds pursuant to ... for clinical development of Asterias, product, AST-OPC1. The ...
(Date:10/20/2014)... VIENNA , October 20, 2014 ... of gastrointestinal (GI) disorders and the delivery of care ... liver diseases and worrying inequalities in the provision of ... survey, which was commissioned by United European Gastroenterology (UEG), ... greater political and public awareness of the burden of ...
(Date:10/20/2014)... PureTech , a science and technology development ... today the closing of a $55 million growth ... a $120 Billion group of funds. The funding ... forward and to advance new healthcare related products ... really go for the big ideas that can ...
Breaking Biology Technology:Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6
... 23, 2011 The Clearity Foundation , ... information to women with ovarian cancer, today announced ... a new position for the organization. The Executive ... as it increases its capacity to support more ...
... At least one dengue vaccine could be licensed within ... the development process for multiple dengue vaccine candidates in ... the necessary testing, clinical trial design, and licensure, a ... number of important issues have been identified for regulatory ...
... from North Carolina State University have developed a ... in microfluidic devices, by using liquid metal. Microfluidic ... a wide variety of applications, from testing minute ... "By making it easier to incorporate electrodes into ...
Cached Biology Technology:The Clearity Foundation Hires Hillary Theakston as Executive Director 2The Clearity Foundation Hires Hillary Theakston as Executive Director 3Capacity of developing country NRAs key to accelerated introduction of upcoming dengue vaccines 2Capacity of developing country NRAs key to accelerated introduction of upcoming dengue vaccines 3Liquid metal key to simpler creation of electrodes for microfluidic devices 2
... DNA polymerase is an antibody-mediated ... both conventional and real-time PCR ... at a concentration of 5 ... 250 units polymerase, 1.25 ml ...
MAb to Mouse MHC Class I H-2Kd...
... GELase™ Agarose Gel-Digesting Preparation contains a ... for simple, quantitative recovery of intact DNA ... agarose gels following electrophoresis in TAE, TBE, ... be digested directly in the TAE, TBE, ...
... GELase™ Agarose Gel-Digesting Preparation contains a unique ... simple, quantitative recovery of intact DNA and ... gels following electrophoresis in TAE, TBE, MOPS, ... digested directly in the TAE, TBE, MOPS, ...
Biology Products: