Navigation Links
UCLA physicists control chemical reactions mechanically
Date:9/17/2010

UCLA physicists have taken a significant step in controlling chemical reactions mechanically, an important advance in nanotechnology, UCLA physics professor Giovanni Zocchi and colleagues report.

Chemical reactions in the cell are catalyzed by enzymes, which are protein molecules that speed up reactions. Each protein catalyzes a specific reaction. In a chemical reaction, two molecules collide and exchange atoms; the enzyme is the third party, the "midwife to the reaction."

But the molecules have to collide in a certain way for the reaction to occur. The enzyme binds to the molecules and lines them up, forcing them to collide in the "right" way, so the probability that the molecules will exchange atoms is much higher.

"Instead of just watching what the molecules do, we can mechanically prod them," said Zocchi, the senior author of the research.

To do that, Zocchi and his graduate students, Chiao-Yu Tseng and Andrew Wang, attached a controllable molecular spring made of DNA to the enzyme. The spring is about 10,000 times smaller than the diameter of a human hair. They can mechanically turn the enzyme on and off and control how fast the chemical reaction occurs. In their newest research, they attached the molecular spring at three different locations on the enzyme and were able to mechanically influence different specific steps of the reaction.

They published their research in the journal Europhysics Letters, a publication of the European Physical Society, in July.

"We have stressed the enzyme in different ways," Zocchi said. "We can measure the effect on the chemical reaction of stressing the molecule this way or that way. Stressing the molecule in different locations produces different responses. If you attach the molecular spring in one place, nothing much happens to the chemical reaction, but you attach it to a different place and you affect one step in the chemical reaction. Then you att
'/>"/>

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California -- Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Applied physicists create building blocks for a new class of optical circuits
2. CU physicists use ultra-fast lasers to open doors to new technologies unheard of just years ago
3. Digging deep into diamonds, applied physicists advance quantum science and technology
4. Rice physicists kill cancer with nanobubbles
5. Diamonds may be the ultimate MRI probe, say Quantum physicists
6. Louisiana Tech physicists highlight top 10 science stories of 2008
7. How do bacteria swim? Brown physicists explain
8. Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue
9. Improving crisis prediction, disaster control and damage reduction
10. Soyscreen: Sunscreen for fungus to expand biological control of crop pests
11. On organic coffee farm, complex interactions keep pests under control
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... our ability to assess the pandemic risk from strains ... we must not allow ourselves to become complacent that ... international consortium of scientists. , Influenza pandemics arise when ... yet to develop widespread immunity – spreads in the ... the past 100 years, the worst of which – ...
(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ("NXT-ID" or ... commerce market releases photos and video of the recent opening bell ... th . Gino Pereira , CEO of ... Mr. Chad A. Verdi rang the bell.  ... and employees "for their work and dedication in bringing the world,s ...
(Date:10/14/2014)... been millions of years since T. rex ... Ohio University scientists is breathing life back into dinosaurs ... snouts. The research has important implications for how dinosaurs ... enhance the sense of smell and cool their brains. ... University doctoral student Jason Bourke, lead author of the ...
Breaking Biology News(10 mins):Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3
... Triticum aestivum ) is one of the "big three" globally ... people. Fully 35% of the world,s 7 billion people depend ... of scientists, including a group from Cold Spring Harbor Laboratory ... genome. The study reveals the evolution of bread ...
... conducting a detailed study of the potential environmental and ... drilling process known as fracking. In hydraulic fracturing, ... deep underground to break apart rock and free trapped ... decades, recent technical advances have helped unlock vast stores ...
... Picture two charged particles in a vacuum. Thanks to ... force these particles exert upon one another, and therefore ... simple medium say, water and the calculation ... water, which in turn may slow, speed, or otherwise ...
Cached Biology News:Bread wheat's large and complex genome is revealed 2Bread wheat's large and complex genome is revealed 3Fracking in Michigan: U-M researchers study potential impact on health, environment, economy 2Fracking in Michigan: U-M researchers study potential impact on health, environment, economy 3Fracking in Michigan: U-M researchers study potential impact on health, environment, economy 4Outside a vacuum: Model predicts movement of charged particles in complex media 2
(Date:10/19/2014)... -- NextCODE Health, which enables clinicians and researchers to use ... announced the launch of its new genomic data analysis and ... Society of Human Genetics (ASHG) annual meeting in ... apply for free beta access, visit www.nextcode.com . A ... viewed here . The Exchange: ...
(Date:10/19/2014)... Asia-Pacific Speech Analytics market report defines and segments the ... of revenue. This market is estimated to grow from ... at a Compound Annual Growth Rate (CAGR) of 23.9% ... of the Asia-Pacific Speech Analytics market report to get ... provides a glimpse of the segmentation in the market, ...
(Date:10/19/2014)... October 19, 2014 The report ... & Homeland Security), Technology, Payload, Type & by ... segments the global unmanned ground vehicle market into ... forecasting of market sizes. The report also identifies ... opportunities impacting it along with the adoption trends. ...
(Date:10/18/2014)... The Asia-Pacific Bio-based Advanced Phase Change ... advanced phase change material market in Asia-Pacific with ... the TOC of the Asia-Pacific Bio-based Advanced Phase ... of the in-depth analysis provided. This also provides ... bio-based advanced phase change material market, and is ...
Breaking Biology Technology:The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 4
... , , Phase Lock Gel may be used in ... total RNA from cell and tissue samples. Increased yields are , ... , without interphase contamination. Below is a protocol outlining ... Reagent and Phase Lock Gel-Heavy. , For further details ...
... , , , , , , ... Eppendorf 5 Prime, Inc. , , , ... It is not convenient in all instances to have blood drawn for gDNA extraction. ... to extract gDNA from , saliva with only slight modifications ...
... , , , , , ... 5 Prime, Inc. , , , , , ... are the least invasive way of collecting gDNA from humans, , ... pathogens. Buccal swabs are quickly becoming the method of choice when , ...
Cached Biology Technology:Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 2Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 3Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 2Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 3Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 4Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 5Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 6Genomic DNA Extraction from Buccal Swabs Using the Perfect gDNA Blood , Mini Kit 2Genomic DNA Extraction from Buccal Swabs Using the Perfect gDNA Blood , Mini Kit 3Genomic DNA Extraction from Buccal Swabs Using the Perfect gDNA Blood , Mini Kit 4Genomic DNA Extraction from Buccal Swabs Using the Perfect gDNA Blood , Mini Kit 5
Large-capacity refrigerated incubator chamber holds up to 4 independently-operated shakers. Programmable heat, refrigeration, humidifcation are standard. Photosynthetic operation, optional....
...
... Advion's NanoMate 100 robotic system and ... full advantage of the capabilities of electrospray ... the NanoMate with MS allows users to ... small molecule and peptide mapping applications, or ...
... Mixes are optimised for SYBR Green I assays ... Quantitative PCR, with the exception of template and ... optimal levels of active SYBR Green I dye ... reaction buffer that enables detection of low copy ...
Biology Products: