Navigation Links
UCLA-led research team finds that bacteria can stand up and walk
Date:10/8/2010

Many drug-resistant infections are the result of bacterial biofilms, structured aggregates of bacteria that live on surfaces and that are extremely resistant to environmental stresses. These biofilms impact human health in many ways cystic fibrosis, for example, is a disease in which patients die from airway bacterial biofilm infections that are invulnerable to even the most potent antibiotics.

Now, UCLA researchers and their colleagues have found that during the initial stages of biofilm formation, bacteria can actually stand upright and "walk" as part of their adaptation to a surface.

"Bacteria exist in two physiological states: the free-swimming, single-celled planktonic state and the surface-mounted biofilm state, a dense, structured, community of cells governed by their own sociology," said Gerard Wong, a professor of bioengineering at the UCLA Henry Samueli School of Engineering and Applied Science and at the California NanoSystems Institute at UCLA.

"Bacteria in biofilms are phenotypically different from free-swimming bacteria even though they are genomically identical. As part of their adaptation to a surface and to the existence of a community, different genes are turned up and down for bacteria in biofilms, leading to drastically different behavior," he said.

In the study, which appears in the current issue of the journal Science, Wong and his research group describe the new surface adaptation the "walking" motility mechanism, which was observed in Pseudomonas aeruginosa, a biofilm-forming pathogen partly responsible for the lethal infections in cystic fibrosis.

What enables this upright walking are appendages called type IV pili, which function as the analog of legs. What's more, walking allows P. aeruginosa to move with trajectories optimized for surface exploration, so that they can forage more effectively. The upright orientation is also the first step in surface detachmen
'/>"/>

Contact: Wileen Wong Kromhout
wwkromhout@support.ucla.edu
310-206-0540
University of California -- Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Notre Dame researcher helps discover walking properties of bacteria
2. In Parkinsons disease, brain cells abandon mitochondria, researchers report
3. MIT researchers develop a better way to see molecules at work in living brain cells
4. US invested $139 billion in health research in 2009
5. Brown Institute for Brain Science marks decade of research impact
6. Scripps Research scientists develop novel test that identifies river blindness
7. Scripps researchers, UCSD chemists to create center devoted to chemistrys influence on climate
8. New fisheries system will save about $20 million, Iowa State University researchers find
9. UNH researcher helps identify key reproductive hormone in oldest vertebrate
10. The world is full of darkness, reflected in the physiology of the human retina, Penn researchers say
11. FSU researchers examine how bacteria become resistant to antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/8/2015)... 8, 2015 Synaptics Inc. (NASDAQ: SYNA ), ... members of the executive management team will present at the ... Media and Telecom Conference Date: May 18, 2015 ... Boston, MA Cowen and Company Technology, ... ET Location: The New York Palace Hotel, New ...
(Date:5/6/2015)... TEL AVIV, Israel , May 6, 2015 /PRNewswire/ ... the world,s most established helmet producer, announced today that ... LifeBEAM Smart Helmet, the world,s first bio-sensing cycling helmet ... will be released in two new colors in order ... demand for the product. In addition, LifeBEAM and Lazer ...
(Date:4/27/2015)... ATLANTA , April 27, 2015  For more ... and trade show has been the premier worldwide event ... Systems 2015 is a must-attend event for any local, ... insight into the emerging commercial markets and current applications ... and innovations of this projected $48 billion industry, and ...
Breaking Biology News(10 mins):Synaptics to Present at Upcoming Investor Conferences 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5
... the latest twist on optical knots, New York University ... extended and knotted optical traps in three dimensions. This ... Society,s (OSA) open-access journal Optics Express , produces ... traces out a knotted trajectory in space, for the ...
... identifying the cause and level of our responses to any ... argues that human beings are more reliant for their behavioural ... that the accuracy of that information is therefore of unparalleled ... of error and deception, which can seriously affect their chances ...
... University of Miami Rosenstiel School of Marine and Atmospheric Science ... 2011 recipient of The Rosenstiel Award, one of the School,s ... Australia,s University of Queensland, is the 37th recipient of the ... limitations of conservation strategies for coral reefs. Mumby began ...
Cached Biology News:Tying the knot with computer-generated holograms: Winding optical path moves matter 2Tying the knot with computer-generated holograms: Winding optical path moves matter 3Peter Mumby to receive prestigious 2011 Rosenstiel Award from the University of Miami 2
(Date:5/27/2015)...  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO ) ("NW ... for cancer, announced today that Dr. Marnix L. ... be making an Industry Expert Theater Presentation at the ... on Saturday, May 30, 2015, from 3 to ... McCormick Place. Dr. Bosch will provide an ...
(Date:5/27/2015)... , May 27, 2015  RXi Pharmaceuticals Corporation ... on discovering and developing innovative therapies primarily in ... update on the status of the Company,s Series ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ... and 21 shares of Series A Preferred Stock ...
(Date:5/26/2015)... Regenestem Network has announced the grand ... Aires, Argentina. The clinic will be lead by Silvina ... assembled a multidisciplinary team of medical professionals who specialize ... Madero office. , The new Regenestem Network members ... studies in cellular therapies, and establish Regenestem protocols to ...
(Date:5/26/2015)... CITY, California and HILDEN, ... QIAGEN N.V. (NASDAQ: QGEN ; ... launch of its QIAGEN Clinical Insight ® ... testing labs to interpret and report on genomic ... two supported applications for the bioinformatics platform are ...
Breaking Biology Technology:NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 2NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 3RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 2RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 3Regenestem Network and Silvina Pastrana, M.D. Announce the Opening of a New Stem Cell Clinic in Buenos Aires 2Regenestem Network and Silvina Pastrana, M.D. Announce the Opening of a New Stem Cell Clinic in Buenos Aires 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 2QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 4QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 5
... 20, 2009 Dates Announced Ergonomics Programs Prove Vital in ... The 15th Annual National Ergonomics Conference and Exposition (NECE) ... - 20, 2009. As of today, nearly a year ... renewed. Exhibitors, including Sherry Rose, Ergonomics Product Manager for ...
... March 5 GeneCopoeia announces the launch of ... tools. They include 1) miExpress(TM) vector based precursor ... (3, UTR) expression clones; and 3) All-in-One(TM) miRNA ... miExpress(TM) precursor miRNA expression clone collections cover ...
... 5 ,Agendia, a world leader in molecular cancer ... (Al) Luderer to its Supervisory Board. , ... 30 years of experience in in vitro medical,diagnostics, ... Chief Executive Officer and President of BioTrove, a ...
Cached Biology Technology:National Ergonomics Conference and Expo Reaches 94% Exhibitor Renewal Rate 2GeneCopoeia Introduces Genome-Wide MicroRNA (miRNA) Functional Analysis Tools 2Agendia Appoints Seasoned Diagnostics Executive Albert A. Luderer to Supervisory Board 2
Lysozyme C (W-20)...
... Blood bank refrigerators: ,Each upright model ... superior 4C temperature uniformity for refrigerated blood. ... 2000 Surveillance Module for complete blood storage ... are equipped with the HemaPro 101 alarm/monitor. ...
... RNase H- Reverse Transcriptase ... version of SuperScript™ II ... SuperScript™ II it synthesizes ... from single-stranded RNA DNA ...
Vapor phase risers are available in various heights to accomodate a variety of inventory solutions. Risers are used to creat a false bottom in which the tanks platform rests and Liquid nitrogen is s...
Biology Products: