Navigation Links
UCLA bioengineers discover how particles self-assemble in flowing fluids
Date:12/13/2010

From atomic crystals to spiral galaxies, self-assembly is ubiquitous in nature. In biological processes, self-assembly at the molecular level is particularly prevalent.

Phospholipids, for example, will self-assemble into a bilayer to form a cell membrane, and actin, a protein that supports and shapes a cell's structure, continuously self-assembles and disassembles during cell movement.

Bioengineers at the UCLA Henry Samueli School of Engineering and Applied Science have been exploring a unique phenomenon whereby randomly dispersed microparticles self-assemble into a highly organized structure as they flow through microscale channels.

This self-assembly behavior was unexpected, the researchers said, for such a simple system containing only particles, fluid and a conduit through which these elements flow. The particles formed lattice-like structures due to a unique combination of hydrodynamic interactions.

The research, published online today in the journal Proceedings of the National Academy of Sciences, was led by UCLA postdoctoral scholar Wonhee Lee and UCLA assistant professor of bioengineering Dino Di Carlo.

The research team discovered the mechanism that leads to this self-assembly behavior through a series of careful experiments and numerical simulations. They found that continuous disturbance of the fluid induced by each flowing and rotating particle drives neighboring particles away, while migration of particles to localized streams due to the momentum of the fluid acts to stabilize the spacing between particles at a finite distance. In essence, the combination of repulsion and localization leads to an organized structure.

Once they understood the mechanism, the team developed microchannels that allowed for "tuning" of the spatial frequency of particles within an organized particle train. They found that by simply adding short regions of expanded channel width, the particles could be
'/>"/>

Contact: Matthew Chin
mchin@support.ucla.edu
310-206-0680
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related biology news :

1. UC San Diego bioengineers fill holes in science of cellular self-organization
2. New method developed by UC San Diego bioengineers gives regenerative medicine a boost
3. Bioengineers succeed in producing plastic without the use of fossil fuels
4. Penn bioengineers create simulator to test blood platelets in virtual heart attacks
5. Bioengineers provide adult stem cells with simultaneous chemical, electrical and mechanical cues
6. Formula discovered for longer plant life
7. Chemical equator discovery will aid pollution mapping
8. Researchers discover that growing up too fast may mean dying young in honey bees
9. Scientists discover why a mothers high-fat diet contributes to obesity in her children
10. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
11. Groundbreaking discovery may lead to stronger antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/8/2015)... July 8, 2015  Trovagene, Inc. (NASDAQ: ... today announced the launch of a study that ... Cancer Monitoring℠ (PCM) technology for predicting response to ... a combination of the novel immunotherapy agents Yervoy® ... PD-1 inhibitor. The 50-patient study will be led ...
(Date:7/7/2015)... Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company") a biometric ... revised version of one of its first 30 second commercials will ... New York , Chicago , ... metro areas.    , , , , ... the cards in your wallet and keep your identity secure. ...
(Date:6/30/2015)... To bolster its efforts and commitment to fighting ... the addition of two new team members. ... David Raviv will act as head of strategic ... to providing the most secure solutions for the enterprise market. ... 7 Technologies, a provider of security and management products, which ...
Breaking Biology News(10 mins):Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3
... NEW YORK, Dec. 8, 2011 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p092465/Global-Biometrics-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Security_ This report ... Thousands of US$ by the following Technologies: ...
... -- New research from Montana State University,s Museum of the ... bones from North America,s biggest dinosaur. In a paper ... researcher Denver W. Fowler and coauthor Robert M. Sullivan from ... the team collected in New Mexico from 2003 to 2006. ...
... seeking a better way to determine the effectiveness of ... a disease that afflicts one in 2,500 people. ... WSU,s School of Medicine, believes the current lack of ... measuring the wrong outcomes. With a four-year, $661,000 Mentored ...
Cached Biology News:Global Biometrics Industry 2Global Biometrics Industry 3Global Biometrics Industry 4Global Biometrics Industry 5Global Biometrics Industry 6Global Biometrics Industry 7Global Biometrics Industry 8Global Biometrics Industry 9Global Biometrics Industry 10Global Biometrics Industry 11Global Biometrics Industry 12Global Biometrics Industry 13Global Biometrics Industry 14Global Biometrics Industry 15Global Biometrics Industry 16Global Biometrics Industry 17Global Biometrics Industry 18Global Biometrics Industry 19Global Biometrics Industry 20Global Biometrics Industry 21Global Biometrics Industry 22Global Biometrics Industry 23Global Biometrics Industry 24New Montana State University, Pennsylvania study reveals North America's biggest dinosaur 2New Montana State University, Pennsylvania study reveals North America's biggest dinosaur 3Better CMT outcome measurement is Wayne State University physician's goal 2Better CMT outcome measurement is Wayne State University physician's goal 3
(Date:7/28/2015)... -- Faced with increasing challenges such as costly treatments ... the global healthcare industry today is gradually transforming ... or significantly changing the course of a disease, ... medicine as a viable alternative. Regenerative ... with the potential to resolve unmet medical needs ...
(Date:7/27/2015)... 27, 2015 /PRNewswire/ - Quest PharmaTech Inc. (TSX-V: QPT) ... commercializing products for the treatment of cancer, today provides ... it has closed a $1,000,000 unit offering private placement.  ... units of the Company at a price of $0.06 ... share and one common share purchase warrant.  Each whole ...
(Date:7/27/2015)... ... 2015 , ... Brady (NYSE:BRC), a global leader ... Ways to GHS Labels . This video provides useful information on how to ... effectively labeling chemical containers. , “With the fourth and final deadline for HazCom/GHS ...
(Date:7/27/2015)... ... July 27, 2015 , ... BlueInGreen® announced ... The venture will bring the world’s most efficient gas dissolution technology to all ... technologies to both the industrial and municipal markets. With offices located in Sarasota, ...
Breaking Biology Technology:Stem Cell Therapy to Redefine Regenerative Medicine, says Frost & Sullivan 2Stem Cell Therapy to Redefine Regenerative Medicine, says Frost & Sullivan 3Stem Cell Therapy to Redefine Regenerative Medicine, says Frost & Sullivan 4Stem Cell Therapy to Redefine Regenerative Medicine, says Frost & Sullivan 5Quest PharmaTech Closes $1,000,000 Private Placement 2Brady Releases “3 Roads to GHS Labels” Video 2BlueInGreen Brings Water Treatment Technology to Florida 2
... Md., July 23 SuperArray,Bioscience Corporation announced today ... moved to a brand new facility three times,larger ... its phenomenal,growth over the last few years and ... expression analysis., "We are not just a ...
... amount of retraction needed for surgical ... ... Technology,today announces the market availability of the SlimFuse(TM) Anterior,Cervical Plate System. ... addressing the clinical needs of,anterior cervical discectomy and fusion (ACDF) surgery., ...
... Del., July 23 More than a third,of ... ) to inquire about the,company,s prescription savings programs ... according to a year-long survey of more than ... of the patients who called,AstraZeneca,s information center regarding ...
Cached Biology Technology:SuperArray Bioscience Changes Name to SABiosciences and Moves Into New Larger Facility on Verge of Tenth Anniversary 2Pioneer(R) Surgical Technology, Inc. Announces the Market Launch of the SlimFuse(TM) Anterior Cervical Plate System 2AstraZeneca Survey: Healthcare Professionals Leading Source of Information on Company's Prescription Savings Programs 2AstraZeneca Survey: Healthcare Professionals Leading Source of Information on Company's Prescription Savings Programs 3
BD BioCoat Laminin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
The F40 piston assembly is supplied as two assemblies to service one F40 pump of a BioLogic DuoFlow workstation....
Mouse monoclonal antibody raised against a full length recombinant ATF3. NCBI Entrez Gene ID = ATF3...
... used as an internal standard for the ... mass spectrometry. 5-OxoETE is a polyunsaturated keto ... in human neutrophils. It stimulates cytosolic calcium ... 2 nM. 5-OxoETE selectively stimulates the migration ...
Biology Products: