Navigation Links
UC nanotech researchers develop artificial pore
Date:9/28/2009

, fungus and bacteria are double stranded, the development of single pore system that can sequence double-stranded DNA is very important," he says.

By being placed into a lipid sheet, the artificial membrane channel can be used to load double-stranded DNA, drugs or other therapeutic material into the liposome, other compartments, or potentially into a cell through the membrane.

Guo also says the process by which the DNA travels through the membrane can have larger applications.

"The idea that a DNA molecule travels through the nanopore, advancing nucleotide by nucleotide, could lead to the development of a single pore DNA sequencing apparatus, an area of strong national interest," he says.

Using stochastic sensing, a new analytical technique used in nanopore work, Wendell says researchers can characterize and identify material, like DNA, moving through the membrane.

Co-first author and UC postdoctoral fellow Peng Jing, PhD, says that, compared with traditional research methods, the successful embedding of the nanomotor into the membrane may also provide researchers with a new way to study the DNA packaging mechanisms of the viral nanomotor. "Specifically, we are able to investigate the details concerning how double-stranded DNA translocates through the protein channel," he says.

The study is the next step in research on using nanomotors to package and deliver therapeutic agents directly to infected cells. Eventually, the team's work could enable use of nanoscale medical devices to diagnose and treat diseases.

"This motor is one of the strongest bio motors discovered to date," says Wendell, "If you can use that force to move a nanoscale rotor or a nanoscale machine you're converting the force of the motor into a machine that might do something useful."


'/>"/>

Contact: Katy Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. New DNA test uses nanotechnology to find early signs of cancer
2. Singapore nanotechnology combats fatal brain infections
3. University awarded £1.7M to develop nanotechnology for use in health care
4. Nanotechnology holds promise for STD drug delivery
5. Donation for new Center for Pharmaceutical Nanotechnology and Nanotoxicology
6. Nanotechnology culture war possible, says Yale study
7. NIST, NCI bring web 2.0 tools to nanotechnology standards effort
8. Survey highlights support for nanotech in health fields but disapproval elsewhere
9. ORNL nanotechnologies big winners in DOE call
10. Nanotechnology boosts war on superbugs
11. Europe rallies behind nanotechnology to wean world from fossil fuels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
(Date:4/2/2015)... , April 2, 2015 At its ... Salt Lake City , the American College of ... five new directors to its Board.  Members of the ... ACMG and for forming and advancing its policies and ... genetics profession. "It,s an eventful time in ...
(Date:3/31/2015)... YORK , March 31, 2015  Elephant Talk ... "Company"), a global provider of Software Defined Network Architecture ... today announced total revenue of approximately $20.4 million for ... a restated $19.5 million for the year ended December ... calendar 2014, the Company had completed its multi-year transition ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... an eco-friendly diesel fuel have more red lights in their ... completely green would not only bend the laws of physics, ... limited, and since we can,t use more than what Earth ... sources like algae," said Peter Pfromm, professor of chemical engineering ...
... drug that will regenerate a critical enzyme in the ... to deadly chemical warfare agents. Christopher Hadad, Ph.D., ... is leveraging Ohio Supercomputer Center (OSC) resources to help ... organophosphorus (OP) nerve agents. "This project is ...
... people collect stamps and coins, but when it comes ... Rice University researcher Michael Deem,s collection of 2.6 million ... natural minerals -- that act as molecular sieves, thanks ... filter, trap and chemically process everything from drugs and ...
Cached Biology News:Economics, physics are roadblocks for mass-scale algae biodiesel production, study finds 2Economics, physics are roadblocks for mass-scale algae biodiesel production, study finds 3Economics, physics are roadblocks for mass-scale algae biodiesel production, study finds 4OSU chemist developing solution to nerve agent exposure 2Exploring the possibilities for zeolites 2
(Date:5/5/2015)... 05, 2015 The Alliance for Clinical ... non-profit operating in the public interest, and Texas-based for-profit ... Hearst Communications Company, have formed a strategic alliance to ... and education across the healthcare and clinical research endeavor. ... of patients and the public to be clearly heard ...
(Date:5/4/2015)... MEMPHIS, Tenn. , May 4, 2015 /PRNewswire-USNewswire/ ... have developed a significantly better computer tool for ... in many cancers but were difficult to identify ... the scientific journal Nature Methods . ... short for Copy Number Segmentation by Regression Tree ...
(Date:5/4/2015)... 2015 /PRNewswire/ - Fluorinov Pharma (Fluorinov), a FACIT ... of Dr. Roger J Garceau, to its Board ... in matters including corporate development and clinical strategy, ... significant regulatory expertise as Fluorinov transitions to clinical ... years of pharmaceutical development experience to Fluorinov and ...
(Date:5/4/2015)... 04, 2015 Achieved primarily through a ... that boast 10 to 100x better detail than the ... of all existing light microscopy methods, it needed another ... chosen as the frame of reference because it represents ... The goal from the earliest discovery days of Ultralight ...
Breaking Biology Technology:ACRES and San Antonio Express-News Launch Blog on Accountability in Clinical Research 2ACRES and San Antonio Express-News Launch Blog on Accountability in Clinical Research 3ACRES and San Antonio Express-News Launch Blog on Accountability in Clinical Research 4Scientists dramatically improve method for finding common genetic alterations in tumors 2Scientists dramatically improve method for finding common genetic alterations in tumors 3Scientists dramatically improve method for finding common genetic alterations in tumors 4Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 2Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 3
... N.J., Nov. 10 Aton Pharma, Inc., ... a recent,survey of ophthalmologists regarding issues in ... dry eye. Aton provides the dry eye ... sustained release prescription insert that helps to ...
... - Seventh Study Showing Oncotype DX Frequently Changes Treatment ... Recommendations in Clinical Practice -, ... GHDX ) today announced the publication of results from ... way,physicians treat early-stage breast cancer. The study, published in the,October ...
... China, Nov. 10 /Xinhua-PRNewswire/ -- 3SBio Inc. (Nasdaq:,SSRX), ... and marketing biopharmaceutical products primarily in China,today announced ... Food and Drug,Administration (SFDA) for approval of NuLeusin ... carcinoma. If approved, NuLeusin is expected to,be the ...
Cached Biology Technology:Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 2Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 3Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 4Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 5Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated 2Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated 3Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated 43SBio Inc. Files for SFDA Approval of NuLeusin 23SBio Inc. Files for SFDA Approval of NuLeusin 33SBio Inc. Files for SFDA Approval of NuLeusin 4
Mouse monoclonal [SH-A1] to S100 alpha ( Abpromise for all tested applications). entrezGeneID: 6271 SwissProtID: P23297...
This application changes sensitive keywords in an FCS file to remove patient information. It was contributed by Dr. David Miller....
Rat monoclonal [HK5.3] to B7 RP1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 23308 SwissProtID: O75144...
Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXS6673E protein). [Source:Uniprot/SWISSPROT;Acc:Q14202] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: