Navigation Links
UC health news: molecular pathway may predict chemotherapy effectiveness
Date:8/31/2007

ff again, says Reed. This suggests that its not just loss of RB that affects therapy responseit could be changes at various steps in cellular signaling that result in different outcomes.

The traditional way of thinking of cancerone cancer gene to treat and youre doneis obviously not the best approach to treating this disease, he adds. These are complex, overlapping molecular pathways. Dissecting them and determining how to use that information to apply combinations of chemotherapeutic agents will allow for individualization of therapy.

Next year, Reed and his colleagues expect to begin testing the RB tumor suppressor in human tumor tissue samples from the UC Thoracic Tumor Registry and compare them to patients with known outcomes.

According to the American Cancer Society, more than 213,000 Americans will be diagnosed with lung cancer in 2007. Because most people are diagnosed late, the five-year survival rate is only 14 percentcompared with 86 percent for breast cancer, 61 percent for colon cancer and 96 percent for prostate cancer.


'/>"/>
Contact: Amanda Harper
amanda.harper@uc.edu
513-558-4657
University of Cincinnati
Source:Eurekalert

Page: 1 2

Related biology news :

1. Chemists create Superbowl molecule; May lead to better health
2. New push for public health, AIDS spending at African Union summit
3. Scientists collaborate to assess health of global environment
4. Highly adaptable genome in gut bacterium key to intestinal health
5. Genetically modified rice in China benefits farmers health, study finds
6. How the environment could be damaging mens reproductive health
7. BioMed Central welcomes the new National Institutes of Health public access policy
8. OneWorld Health drug receives Orphan designation from U.S. and European regulatory agencies
9. Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
10. Health costs soar as 60 million Americans classed as obese
11. Study of energy and health in Africa focuses spotlight on charcoal and forest management
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... For decades, scientists have used techniques like X-ray crystallography ... insight into the atomic structure of molecules, but such ... they demand large quantities of a specific molecule and ... making it all but impossible to peer into ... say those problems may soon be a thing of ...
(Date:4/18/2014)... twist to the story of how barnyard chickens came to ... the journal Proceedings of the National Academy of Sciences ... lived 200-2300 years ago in Europe, researchers report that just ... far different from the chickens we know today. , The ... modern domestic chickens -- such as their yellowish skin -- ...
(Date:4/18/2014)... A team of researchers led by a University ... to receive a $7.5 million Department of Defense grant ... basic scientific foundations for the predictable design of light-weight, ... diversity of structures from plants and animals, including the ... what biological systems have constructed over millions of years ...
Breaking Biology News(10 mins):MRI, on a molecular scale 2MRI, on a molecular scale 3Ancient DNA offers clues to how barnyard chickens came to be 2Mantis shrimp, toucan and trilobite, oh my 2Mantis shrimp, toucan and trilobite, oh my 3
... Holick, a professor of medicine, physiology and biophysics at ... the understanding of vitamin D and its role in ... Prize for Health Research. The prize was presented ... by the Linus Pauling Institute at Oregon State University. ...
... this summer,s lineup of lectures called Distinctive Voices@The ... Hole, Massachusetts, feature diverse subjects for those curious ... the program will explore science and technology,s role ... and creativity. Award-winning scientists and engineers -- ...
... made new inroads into understanding the regulatory circuitry of ... of daily activities, according to two studies published May ... clocks and temperature, reported in Cell , offers ... the 24-hour circadian rhythm does not change with temperature ...
Cached Biology News:Vitamin D expert receives Linus Pauling Prize for Health Research 2Woods Hole lecture series explores range of scientific topics 2Two new studies on circadian rhythms 2
(Date:1/14/2014)... 14, 2014 The largest international professional organization ... and therapeutic derivatives thereof has endorsed an educational ... about the challenges of adulterated herb and botanical ... The Society for Medicinal Plant and ...
(Date:1/14/2014)... In recent years, growing suspicion about the ... development and promotion has led to unprecedented levels of ... concerns about the insidious impact of commercialization of research, ... to the world’s biggest pharmas for illegal marketing activities, ...
(Date:1/14/2014)... 14, 2014   Kinaxis ®, provider of RapidResponse ®, ... and operations planning ( S&OP ) service, is proud to ... which will be held at the Hilton San Diego Bayfront, ... customer Elisabeth Kaszas , Director of Supply Chain at ...
(Date:1/14/2014)... 14, 2014 During the 1600’s through the ... “The Doctor’s Plague.” In this time period, doctors did not ... at times, to the death of vulnerable patients. In the ... that they may be unwittingly transmitting herpes viruses to their ...
Breaking Biology Technology:World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... More Effective Than rituximab ... in a Pre-Clinical ... announced today that ofatumumab (HuMax-CD20(R)) appeared more,effective at inducing complement ... a pre-clinical study. The CD20,antibodies were incubated with tumor cells ...
... YORK, Sept. 6 Globally, approximately 418 million,people ... danger, and costs of hepatitis in the 21st ... Hepatitis Strategies, a,new report by Kalorama Information. ... not,taking the necessary steps to contain hepatitis. Yet ...
... Globally, approximately 418 billion,people are currently infected with ... hepatitis in the 21st century cannot be,understated or ... by Kalorama Information. Paradoxically, despite the obvious ... to contain hepatitis. Yet the incidence and,prevalence of ...
Cached Biology Technology:Genmab Announces Encouraging Preclinical Data for ofatumumab 2Touching 418 Million Lives, Hepatitis Still Presents Significant Threat to Global Health 2Touching 418 Billion Lives, Hepatitis Still Presents Significant Threat to Global Health 2
... trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl ... latanoprost-related isomer containing both a double ... (β) hydroxyl group at C-15. Similar ... ester is a potential impurity in ...
... new product number, created to easily match ... yet, please order under the old Sigma-Aldrich ... assistance. Feature: tissue-culture treated yes ... cm 2 D H 60 ...
... bind specifically to Fc regions of many ... conjugates are commonly used as affinity adsorbents ... from serum, hybridoma ascites fluids, tissue culture ... are also commonly used to capture immune ...
... min) assay can detect H2O2 or peroxidase ... H2O2 oxidizes ADHP in a 1:1 stoichiometry ... at 530-571 nm, emission at 590-600 nm). ... a one-step, homogeneous, no wash assay system. ...
Biology Products: