Navigation Links
UC Santa Cruz builds national data center for cancer genome research
Date:5/1/2012

molecular detail," Haussler said. "Cancer is a disease caused by disruption of DNA molecules within the cell. When life starts, every cell in the body has the same DNA. In the course of a person's lifetime, however, some cells may accumulate changes in their DNA that cause them to go rogue and multiply without control, creating the disease we call cancer. For the first time now, we are able to look into an individual patient's cancer cells and see all the genetic disruptions, among which are the molecular drivers of that person's cancer."

There are currently only a few situations in which doctors can prescribe a treatment plan based on the specific genetic mutations in a patient's cancer cells. That is expected to change as projects like TCGA, TARGET, and CGCI yield a comprehensive catalog that researchers can use to find new targets for medicines and discover clues to improve patient outcomes. But there is an urgent need for an efficient and user-friendly portal to give researchers access to the data. The NCI genome projects are producing staggering amounts of data.

"The scale of this is far beyond anything faced in medical research before," Haussler said. "Each genome file, the DNA record from a tumor or normal tissue, is 300 billion bytes. And for every case there are two of these files, the cancer genome and the normal genome. Add to this RNA sequence data, and the prospect of deeper sequencing in the future, and we must plan for up to a terabyte (1,000 billion bytes) for each case."

TCGA currently generates about 10 terabytes of data each month. For comparison, the Hubble Space Telescope amassed about 45 terabytes of data in its first 20 years of operation. TCGA's output will increase tenfold or more over the next two years. Over the next four years, if the project produces a terabyte of DNA and RNA data from each of more than 10,000 patients, it will have produced 10 petabytes of data (a petabyte is 1,000 terabytes). And TCGA is jus
'/>"/>

Contact: Tim Stephens
stephens@ucsc.edu
831-459-2495
University of California - Santa Cruz
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
2. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
3. UC Santa Barbara researchers new study may lead to MRIs on a nanoscale
4. University of California Santa Barbara study reveals how gas, temperature controlled bacterial response to Deepwater Horizon spill
5. Argentinas Santa Fe government reducing lead ammunition for sports hunters
6. New data published in Nature Genetics demonstrate that tiny LNA-based compounds developed by Santaris Pharma A/S inhibit entire disease-associated microRNA families
7. Marine Protected Areas Federal Advisory Committee meets Nov. 2-3 in Santa Barbara
8. Santa Fe homeowners weigh in on landscape preferences
9. Researchers study effect of yuma desalting plant on Cienega de Santa Clara
10. CNIC and Banco Santander set up research project on early cardiovascular risk factors
11. UC Santa Barbara and Burnham Institute for Medical Research announce director
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... -- Nxt-ID, Inc. (Nasdaq: NXTD and NXTDW) ("Nxt-ID" ... m-commerce market, updates the "Wocket in Your Pocket" celebrity ad campaign, ... middleweight weight classes, Vinny Pazienza (PAZ). ... of Thrones actor Ciaran Hinds and Sons ... Katey Sagal have been cast in Bleed for This ...
(Date:9/18/2014)... PULLMAN, Wash. - Washington State University researchers have developed ... sediment to power waste cleanup in rural areas. ... lead to an inexpensive and quick way to clean ... treatment plants while reducing pollution. , Professor Haluk ... College of Engineering and Architecture discuss the system in ...
(Date:9/18/2014)... located deep in the primitive brainstem has revealed how ... Harvard School of Medicine and the University at Buffalo ... the second "sleep node" identified in the mammalian brain ... to produce deep sleep. , Published online in August ... fully half of all of the brain,s sleep-promoting activity ...
Breaking Biology News(10 mins):NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 2NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 3Researchers develop unique waste cleanup for rural areas 2No sedative necessary: Scientists discover new 'sleep node' in the brain 2
... not just be helping digest food but also could be ... other organs, like the liver, according to research published this ... offer new understanding of the symbiotic relationship between humans and ... impact overall health. "The gut microbiota enhances the host,s ...
... of Medicine researchers have identified two genes associated with ... effective treatments for excessive alcohol drinking. The scientists found ... and toll-like receptor 4 (TLR4), "caused profound reduction" of ... been bred and trained to drink excessively. The study ...
... America have been awarded Leopold Leadership Fellowships for ... Institute for the Environment, the Leopold Leadership Program ... make their knowledge accessible to decision makers. ... mid-career academic environmental researchers as fellows. They receive ...
Cached Biology News:Gut bacteria can control organ functions 2University of Maryland School of Medicine study identifies genes associated with binge drinking 2University of Maryland School of Medicine study identifies genes associated with binge drinking 3University of Maryland School of Medicine study identifies genes associated with binge drinking 420 researchers selected as 2011 Leopold Leadership Fellows 220 researchers selected as 2011 Leopold Leadership Fellows 320 researchers selected as 2011 Leopold Leadership Fellows 4
(Date:9/19/2014)... 2014 Cereal grain scientists, quality ... gather October 5–8, 2014, for the AACC International ... Center in Providence, Rhode Island. The comprehensive scientific ... food scientists, chemists, microbiologists, nutritionists, and those interested ... management. To date, 1,000 attendees have registered for ...
(Date:9/18/2014)... HealthTronics, Inc ., a ... products and services, announced that a poster related ... versus external beam radiotherapy (EBRT) is being presented ... Association (MAAUA) Annual Meeting in Baltimore, Maryland September ... Cryosurgery and External Beam Radiation as Treatments for ...
(Date:9/18/2014)... DUBLIN, Ireland , September 18, ... ,Research and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) ... "Biocompatible Materials - Global Strategic ... offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report ... Materials in US$ Million by the ...
(Date:9/18/2014)... 18, 2014 Research and Markets ... Albumin Industry Report 2014" report to their offering. ... 2014 is a professional and in-depth study on the ... The report provides a basic overview of the ... The human albumin market analysis is provided for the ...
Breaking Biology Technology:Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3
... Sept. 13 Allos,Therapeutics, Inc. (Nasdaq: ALTH ... commercialization of small molecule therapeutics for,the treatment of ... and,CEO, will present a corporate overview at the ... The Company,s presentation will take place at ...
... a world leader in,the rapidly evolving field of cancer ... H. M. Lindenbergh as Chairman of its,Supervisory Board. ... board of ING,Group N.V.. Currently, Mr. Lindenbergh is chairman ... member of the Royal Numico, Petroplus,International and Gamma Holding. ...
... ADVENTRX Pharmaceuticals,Inc. (Amex: ANX ), ... commercializing proprietary product candidates for the treatment,of ... Evan M. Levine,ADVENTRX,s chief executive officer, is ... Annual Growth Conference on Wednesday,September 19th, 2007 ...
Cached Biology Technology:Allos Therapeutics to Present at the 2007 UBS Global Life Sciences Conference 2Agendia BV Appoints Mr. Hessel Lindenbergh as Chairman of its Supervisory Board 2ADVENTRX Pharmaceuticals to Present at the ThinkEquity Partners' Fifth Annual Growth Conference 2
... Waterproof, moisture-proof film prevents sample evaporation, ... folded repeatedly and twisted around sharp ... 21C (70F), wrapping film increases approximately ... film only partially returns to original ...
PlusOne EDTA, disodium salt, 100 g. Category: Electrophoresis Systems & Standards & Reagents, Electrophoresis Standards and Reagents, Buffers....
...
Normal human serum collected off the clot from healthy normal humans. Each donor unit is negative for anti-HIV 1&2, HIV-Ag, HCV, and HBsAg by FDA required tests...
Biology Products: