Navigation Links
UC Santa Barbara researchers develop synthetic platelets
Date:5/30/2012

to not only perform the typical functions of human platelets; but may also be used to carry imaging agents to identify damaged blood vessels or to deliver drugs that dissolve blood clots.

The synthetic platelets represent the latest and one of the most advanced in a line of efforts over the last century to mimic platelet function. While clotting factors and platelets from outside donors are used widely to halt bleeding, immune system responses and thrombosis have been issues. Non-platelet-derived substitutes have also received attention; however, said Doshi, these do not physically resemble the physical features of natural platelets.

"This development is a significant milestone in the field of biomimetic materials," said Samir Mitragotri, professor of chemical engineering, director of UC Santa Barbara's Center for Bioengineering, and an author of the paper. "By capitalizing on our capabilities in engineering materials, with the expertise in platelet biology that exists in Professor Ruggeri's laboratory, our synthetic platelets combine unique physical and biological attributes that mimic natural platelets." Biomaterials research is one of the principal focus areas in UCSB's Center for BioEngineering. In 2009, Doshi and colleagues in the Mitragotri laboratory developed synthetic red blood cells.

"This work is a marvelous demonstration of the power of material synthesis applied to medical problems. The synthetic platelets can have profound implications in wound-healing problems for trauma and wounds arising in both battlefield situations and during surgery," said Frank Doyle, director of UCSB's Institute of Collaborative Biotechnologies and the Associate Dean of Research of UCSB's College of Engineering.

Other authors of the study include Jennifer N. Orje, Blanca Molins, and Zaverio Ruggeri from Scripps Research Institute; and Jeffrey Smith from Sanford-Burnham Medical Research Institute.


'/>"/>

Contact: Sonia Fernandez
sonia.fernandez@ia.ucsb.edu
805-893-4765
University of California - Santa Barbara
Source:Eurekalert  

Page: 1 2

Related biology news :

1. UC Santa Cruz builds national data center for cancer genome research
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
4. UC Santa Barbara researchers new study may lead to MRIs on a nanoscale
5. University of California Santa Barbara study reveals how gas, temperature controlled bacterial response to Deepwater Horizon spill
6. Argentinas Santa Fe government reducing lead ammunition for sports hunters
7. New data published in Nature Genetics demonstrate that tiny LNA-based compounds developed by Santaris Pharma A/S inhibit entire disease-associated microRNA families
8. Marine Protected Areas Federal Advisory Committee meets Nov. 2-3 in Santa Barbara
9. Santa Fe homeowners weigh in on landscape preferences
10. Researchers study effect of yuma desalting plant on Cienega de Santa Clara
11. CNIC and Banco Santander set up research project on early cardiovascular risk factors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UC Santa Barbara researchers develop synthetic platelets
(Date:10/16/2014)... can be cultivated efficiently, they are anything but ... by monoculture cultivation is becoming increasingly evident. Despite ... form and are regarded as the sole possibility ... quite wrongfully, finds Bernhard Schmid, an ecology professor ... novel form of agriculture and forestry. After all, ...
(Date:10/15/2014)... the pandemic risk from strains of influenza virus increases ... ourselves to become complacent that the most substantial threats ... , Influenza pandemics arise when a new virus strain ... immunity – spreads in the human population. There have ... the worst of which – the 1918 Spanish Flu ...
(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... growing mobile commerce market releases photos and video of the recent ... October 13 th . Gino Pereira , ... angel investor Mr. Chad A. Verdi rang the bell.  ... his investors and employees "for their work and dedication in bringing ...
Breaking Biology News(10 mins):Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
... entire lives as parasites on birds, it is difficult ... the University of Gothenburg, Sweden, reveals. Researcher Daniel ... world and investigated how host birds, migration patterns affect ... very small eyes, chewing lice are, by and large, ...
... temperature of the food we eat affect the intensity of ... new study by Dr. Gary Pickering and colleagues from Brock ... temperature of foods and drinks have an effect on the ... but not sweetness. Their work is published online in Springer,s ...
... first in a series of annual literature reviews ... was recently released by Society of Interventional Radiology ... expanding, and it has become increasingly difficult for ... volume of literature required to remain current," said ...
Cached Biology News:Hitch-hiking with birds for life 2To get the full flavor, you need the right temperature 2'Updates in Interventional Radiology' accents emerging trends, practice growth 2
(Date:10/22/2014)... October 22, 2014 Involution Studios ... release of a new infographic, Understanding Ebola . ... a beautifully designed, easy to follow informative tool for ... of outbreak, symptoms and prevention. , "As the news ... the 2014 Ebola outbreak represents not only a healthcare ...
(Date:10/22/2014)... October 22, 2014 Physicians Choice ... cardiovascular pharmacogenetics menu, which enables healthcare providers to ... With PCLS’s evidence-based results, healthcare providers are better ... their therapy, while minimizing risks for adverse drug ... according to the FDA [1] more than 2.2 ...
(Date:10/22/2014)... 22, 2014 Nuvilex, Inc. (OTCQB: NVLX) – ... people worldwide are living with diabetes, with  that number ... The global market for diabetes treatments is approximately $500 ... worldwide died from pancreatic cancer.  Pancreatic cancer is the ... in the United States , and ...
(Date:10/20/2014)... Oct. 20, 2014 Mapp Biopharmaceutical,s valiant ... antibody therapeutic to fight the Ebola outbreak will ... time-consuming the production of pharmaceuticals can be, according ... said that while some may be taken aback ... those with industry knowledge are well aware of ...
Breaking Biology Technology:Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 3Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3
... U.S. Department of Energys Brookhaven National Laboratory have developed ... and micrometer-sized particles. The method, based on designed DNA ... to manipulate the structure and therefore the properties ... be of interest to industry. For example, such fine-tuning ...
... 12 BioReliance Corporation, a,leading contract services ... contracted with Gentronix to offer their,GreenScreen HC ... of BioReliance,s portfolio of,genotoxicity screening services. GreenScreen ... pharmaceutical companies to test for genotoxic potential,earlier ...
... Inc. (Nasdaq:,PPDI) today announced Daniel G. Darazsdi has ... position on October 1. Mr. Darazsdi, 47, ... a $34 billion diversified technology and manufacturing,leader, where ... CFO of finance,transformation and operations. Over the years ...
Cached Biology Technology:New DNA-based technique for assembly of nano- and micro-sized particles 2BioReliance Launches Next-Generation Genotoxicity Screening Service 2PPD Names Daniel Darazsdi as Chief Financial Officer 2PPD Names Daniel Darazsdi as Chief Financial Officer 3
... For the ultimate in utility and ... to meet the needs of the researcher. ... interior dimensions or as sheet material that ... enclosures. These isolators are autoclavable and non-cytotoxic ...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
IC50: 3 ng/ml · Limit of detection: 0.5 ng/ml...
Antibodies were affinity purified using epitopes specific to PPP1CC immobilized on solid support....
Biology Products: