Navigation Links
UC San Diego researchers use metagene 'portraits' to reveal distinct stages of kidney formation
Date:12/11/2008

s (SOMs).

Essentially acting as unsupervised learning neural networks, SOMs cluster genes with similar temporal expression profiles into metagene portraits. In this case, the SOMs were collected using microarray gene expression data and a high-dimensional data analysis program called Gene Expression Dynamics Inspector, or GEDI. UC San Diego scientists then performed a detailed time-series analysis of the kidney SOMs reflecting various stages of organogenesis. That was followed by entropy calculations for each SOM to measure the differences in states during the various stages, before correlating these results with morphometric parameters and specific gene networks.

Taken together, analysis of the metagene portraits suggested that kidney formation could be divided into as many as eight distinct stages.

"Although there is morphological support for the notion of stages, the beginning and end points of those stages can be difficult to define because many basic morphogenetic processes occur simultaneously," said Tsigelny. "Our research suggests that with the metagene analysis and entropy calculations, global gene expression can be used to more clearly define these stages and allow us to have a fuller understanding about how organs form."


'/>"/>

Contact: Jan Zverina
jzverina@sdsc.edu
858-534-5111
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related biology news :

1. Field-hospital-on-a-chip project awarded to nanoengineer from UC San Diego
2. San Diego Supercomputer Center and UCSD announce Triton Resource
3. UC San Diego bioengineers fill holes in science of cellular self-organization
4. NIH doles out $3M in new innovator awards to 2 UC San Diego faculty
5. Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering
6. UC San Diego researchers could help US military thwart explosive threats
7. UC San Diego launches Institute of Engineering in Medicine to accelerate health care tech
8. UC San Diego researchers identify potential new drug candidates to combat bird flu
9. Glowing films developed by UC San Diego chemists reveal traces of explosives
10. UC San Diego researchers eliminate drug discovery bottleneck
11. Biologists at UC San Diego identify key protein in cells self-eating function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Valencell, a leader in performance biometric data sensor ... leaders such as Intel, Jabra, Atlas, and Scosche to ... These products will be showcased at CES 2015, taking ... . "Our partners choose PerformTek biometrics, ...
(Date:12/11/2014)... Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... addition of the "Biometrics Market in India 2015-2019" ... major trend emerging in this market is the adoption ... than one characteristic of an individual for verification and ...
(Date:12/10/2014)... Dec. 9, 2014  Wake Forest Baptist Medical Center today announced ... of Medicine. Funding for this $50 million capital project is ... launched next summer. The medical education building ... Tobacco Company complex, adjacent to 525@vine in Wake Forest Innovation ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... reviews of nutrition related topics raises unique challenges ... In a new article, a team of researchers ... and limitations of systematic reviews relevant to nutrition ... Systematic reviews, also referred to as ...
... 2008 - The International Atomic Energy Agency (IAEA) today ... that could bolster efforts aimed at pulling millions of ... use radiation to produce improved high-yielding plants that adapt ... or that are resistant to certain diseases and insect ...
... benefit from a powerful new database, available for free ... the parts of proteins most necessary for their function. ... of genetics at the Stanford University School of Medicine, ... as the guide to determining the role different proteins ...
Cached Biology News:Experts discuss applying systematic review to the field of nutrition 2Nuclear science for food security 2Powerful online tool for protein analysis provided pro bono by Stanford geneticist 2Powerful online tool for protein analysis provided pro bono by Stanford geneticist 3
(Date:1/23/2015)... 23, 2015 Biofertilizers stimulate microbial activities ... nitrogen and phosphorous through the activities in the soil ... increasing due to the stress on reducing environmental pollution ... The report defines and segments the bio fertilizers market ...
(Date:1/22/2015)... | RBJ today announces the firm brokered a long-term lease ... leading biopharmaceutical company, at Two Ledgemont Center in ... , president, and Brian Cohen , senior vice president, ... at 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... 22, 2015 Protocol Networks brings independent ... team of brand-neutral, independent consultants, Protocol Networks has recently ... that over the years, his company has attracted several ... of Plainfield, as well as others. With the success ...
(Date:1/22/2015)... 22, 2015 Controlled Substance Compliance Services ... helps companies check the legal requirements around using controlled ... China. , As their international operations expand and ... software solutions built as a result of the first ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Global Compliance Service for Controlled Substances to Expand to China 2
... Calif., Oct. 10 Neurobiological,Technologies, Inc. (NTI(R)) (Nasdaq: ... on Monday, October 13, to provide an update on ... stroke.,Hosting the call will be Paul E. Freiman, president ... officer., -- Date: Monday, October 13, ...
... effects of, recombinant lactoferrin (tradename: Lacromin) in mammalian ... leading to a significant boost ... A recently published study,in the scientific journal In Vitro ... see, http://www.Lacromin.com ) is a strong growth factor for ...
... CORPUS CHRISTI, Texas, Oct. 10 CSMG,Technologies, ... management,company, announced the company has received approval ... on a key divisional application for "Bonding ... Electric Current,Therethrough" for CSMG Technologies subsidiary Live ...
Cached Biology Technology:Neurobiological Technologies Announces Update Call on Viprinex (TM) Phase 3 Trial Program 2New Study Finds Growth Factor Boosts Productivity in Mammalian Cell Culture 2CSMG Technologies Announces Key Fifth U.S. Tissue Bonding/Welding Patent Approved 2CSMG Technologies Announces Key Fifth U.S. Tissue Bonding/Welding Patent Approved 3
... For use with T4 Polynucleotide ... (5' phosphate ends) of nucleic acids. ... Kinase transfers the 5' phosphate group ... transfers the Gamma-phosphate of ATP to ...
ImageQuant 400, 1 EA. Category: ImageQuant CCD Imagers....
...
...
Biology Products: