Navigation Links
UC San Diego researchers use metagene 'portraits' to reveal distinct stages of kidney formation
Date:12/11/2008

s (SOMs).

Essentially acting as unsupervised learning neural networks, SOMs cluster genes with similar temporal expression profiles into metagene portraits. In this case, the SOMs were collected using microarray gene expression data and a high-dimensional data analysis program called Gene Expression Dynamics Inspector, or GEDI. UC San Diego scientists then performed a detailed time-series analysis of the kidney SOMs reflecting various stages of organogenesis. That was followed by entropy calculations for each SOM to measure the differences in states during the various stages, before correlating these results with morphometric parameters and specific gene networks.

Taken together, analysis of the metagene portraits suggested that kidney formation could be divided into as many as eight distinct stages.

"Although there is morphological support for the notion of stages, the beginning and end points of those stages can be difficult to define because many basic morphogenetic processes occur simultaneously," said Tsigelny. "Our research suggests that with the metagene analysis and entropy calculations, global gene expression can be used to more clearly define these stages and allow us to have a fuller understanding about how organs form."


'/>"/>

Contact: Jan Zverina
jzverina@sdsc.edu
858-534-5111
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related biology news :

1. Field-hospital-on-a-chip project awarded to nanoengineer from UC San Diego
2. San Diego Supercomputer Center and UCSD announce Triton Resource
3. UC San Diego bioengineers fill holes in science of cellular self-organization
4. NIH doles out $3M in new innovator awards to 2 UC San Diego faculty
5. Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering
6. UC San Diego researchers could help US military thwart explosive threats
7. UC San Diego launches Institute of Engineering in Medicine to accelerate health care tech
8. UC San Diego researchers identify potential new drug candidates to combat bird flu
9. Glowing films developed by UC San Diego chemists reveal traces of explosives
10. UC San Diego researchers eliminate drug discovery bottleneck
11. Biologists at UC San Diego identify key protein in cells self-eating function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... and the bees. But that old expression leaves ... fertilization process for flowering plants is particularly complex ... female reproductive cells. New research from an international ... including Carnegie,s Wolf Frommer, David Ehrhardt, and Guido ... that guides flowering plant fertilization. It is published ...
(Date:8/21/2014)... 21, 2014 Nxt-ID, Inc. (OTCQB: NXTD), a ... market, announced today that its shares of common stock ... issued in its proposed underwritten public offering of common ... The Nasdaq Capital Market, subject to closing of its ... warrants, and will trade under the symbol "NXTD" and ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- LiveScan ... has agreed to a partnership with Gabriel Health ... fastest growing Certified Nursing Assistant preparatory ... Institute  an exclusive member of Binary,s LiveScan service ... Biometrics will improve its service capabilities by ...
Breaking Biology News(10 mins):Calcium and reproduction go together 2Nxt-ID Approved for NASDAQ Capital Market Listing 2Nxt-ID Approved for NASDAQ Capital Market Listing 3LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3
... invasive species move into new areas, they often lose their ... new research from evolutionary biologists at the University of South ... help house sparrows, one of the world,s most common bird ... in Proceedings of the Royal Society B , Biological ...
... FAHA, Director of the Cardiovascular Research Center (CVRC) at ... heart for nearly three and a half decades. Over ... research, work that led to his recent recognition with ... the Basic Cardiovascular Science (BCVS) Council Distinguished Achievement ...
... relatives of papaya were certain trees from the Andes, the ... species of the papaya family instead revealed that the closest ... tree with stinging hairs occurring from Mexico to Guatemala and ... from cloud forests in the Sierra de Juarez in Oaxaca, ...
Cached Biology News:USF researchers show invasive sparrows immune cells sharpen as they spread 2Temple's Dr. Steven Houser recognized by the American Heart Association 2Temple's Dr. Steven Houser recognized by the American Heart Association 3
(Date:8/22/2014)... Nerium International, the go-to, buzzworthy skincare ... again. Nerium will showcase its signature NeriumAD® Age-Defying ... Cream to Hollywood’s elite at the official Giving ... Primetime Emmy® Awards. , Developed from cutting-edge research ... show that NeriumAD night cream dramatically reduces the ...
(Date:8/21/2014)... A Finnish-Swedish research group at the Institute for ... Karolinska institutet, Stockholm, has developed a novel "man ... infection. This innovative diagnostic aid was described in ... August. The method is based on computer vision ... systems combined with visualization of only the diagnostically ...
(Date:8/21/2014)... 2014 Telomere Biosciences, LLC (Telomere Biosciences) ... for Dogs" with Telomerase Activation Complex , ... world for dogs. Telomeres are the protective caps ... body. A wealth of ground-breaking research by some ... and Aging, including Nobel laureates, has demonstrated a ...
(Date:8/21/2014)... Aug. 21, 2014  China Cord Blood Corporation (NYSE: ... to release financial results for the first quarter of ... market close in the US.  The ... ET on Friday, August 29, 2014 to discuss its ... Company,s recent developments, followed by a question and answer ...
Breaking Biology Technology:Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2
... 4, 2011 Reportlinker.com announces that a ... its catalogue: Nanotechnology in ... Approaches to Fulfill High Potential ... in Drug Delivery - Technological Improvements and ...
... NEW YORK, Jan. 4, 2011 Reportlinker.com announces ... in its catalogue: Financial Health ... China http://www.reportlinker.com/p0357094/Financial-Health-of-Biotechnology-and-Drugs-Industry-in-India-and-China.html ... of Indian and Chinese biotechnology companies across 2 ...
... BEACH, Calif., Jan. 4, 2011 Genesis Biopharma, Inc. ... company developing targeted cancer therapies, today announced that it ... to which it entered into definitive agreements with accredited ... the Genesis Biopharma common stock for a purchase price ...
Cached Biology Technology:Reportlinker Adds Nanotechnology in Drug Delivery - Technological Improvements and Novel Approaches to Fulfill High Potential 2Reportlinker Adds Financial Health of Biotechnology and Drugs Industry in India and China 2Genesis Biopharma Raises $845,000 in Private Financings 2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)...
... terminators, template DNA, primers, salts or other ... have proved critical for both standard and ... work with dye terminator cycle sequencing chemistries ... unique uniformity of the magnetic paeticles guarantees ...
Mature rat whole blood (Sprague-Dawley, averaging 7-8 weeks of age, either sex) is collected at the time of slaughter and processed within 45 minutes. It is then filtered through gauze, pooled in an ...
X-gal,1g...
Biology Products: