Navigation Links
UC Riverside cell biologist to investigate how malaria parasite multiplies in red blood cells
Date:11/4/2010

RIVERSIDE, Calif. Today, about half the world's population lives in areas at risk of malaria transmission. The disease is transmitted to humans through bites from mosquitoes, and each year causes hundreds of thousands of deaths worldwide, with about 1,500 of these in the United States.

The malaria-causing parasite, Plasmodium falciparum, is spread to people by the female Anopheles mosquito, which feeds on human blood. P. falciparum invades red blood cells, where it grows and multiplies. Eventually, the red blood cells burst, releasing into the bloodstream thousands of parasites that invade other red blood cells and continue the infection cycle.

Just how the human malaria parasite replicates itself inside red blood cells is, however, not well understood. Now a researcher at the University of California, Riverside has received a nearly $1.7 million four-year grant from the National Institute of Allergy and Infectious Diseases, the National Institutes of Health, to address this question.

"If we manage to understand how the parasite multiplies in the red blood cells, we will be able to develop more effective strategies for combating malaria," said Karine Le Roch, an assistant professor of cell biology and neuroscience and the grant's principal investigator. "The long term goal is to devise new drug strategies against this devastating disease."

Stefano Lonardi, an associate professor of computer science and engineering, will assist in the computational analysis of the massive amount of data produced by the sequencing instruments.

"The analysis pipeline is complex, but in the end we would like our software tools to generate a set of hypotheses of gene regulation for the malaria genome that Karine can test or validate in the lab," Lonardi said.

The grant will support one technician, one postdoctoral researcher and one Ph.D. graduate student. An expert in proteomics and mass spectrometry from the Stowers Institute, Kan., will collaborate.


'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Related biology news :

1. UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants
2. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist
3. UC Riverside scientist to explore how vegetation affects urban heat islands
4. UC Riverside rice geneticist receives high honor from US Department of Agriculture
5. UC Riverside biochemist to study how crops can increase protein production
6. UC Riverside researcher names lichen after President Barack Obama
7. UC Riverside professor receives top scientific honor
8. UC Riverside geneticist receives highest honor from Botanical Society of America
9. Public lecture at UC Riverside to discuss origin and fate of universe
10. UC Riverside student is 1 of only 5 persons selected for challenging Arctic expedition
11. UC Riverside research on barley genome gets boost from $1 million USDA grant
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UC Riverside cell biologist to investigate how malaria parasite multiplies in red blood cells
(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
(Date:3/24/2017)... Research and Markets has announced the addition of the "Global ... to 2025" report to their offering. ... The Global Biometric Vehicle Access System Market ... the next decade to reach approximately $1,580 million by 2025. ... for all the given segments on global as well as regional ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... , ... August 15, 2017 , ... ... family of 6” modular downlights designed to stay tightly sealed and perform efficiently ... where damp and wet location listings just aren't enough, such as: hospitals; behavioral ...
(Date:8/14/2017)... , ... August 14, 2017 , ... ... and performing antibodies. Key researchers in the antibody community have recently come together ... consistency for antibodies in the laboratory. , The team at ...
(Date:8/11/2017)... ... , ... A staple in the community for more than 60 years, Bill ... including a new digital marketing strategy and updated logo. , As part of the ... with the South Texas Blood & Tissue Center for the month of August. ...
(Date:8/10/2017)... , ... August 09, 2017 , ... ... classroom next week-- as students. From August 14th through the 16th, the University ... which debuted in the summer of 2016, provides Philadelphia-based middle school educators an ...
Breaking Biology Technology: