Navigation Links
UC Riverside cell biologist to investigate how malaria parasite multiplies in red blood cells
Date:11/4/2010

RIVERSIDE, Calif. Today, about half the world's population lives in areas at risk of malaria transmission. The disease is transmitted to humans through bites from mosquitoes, and each year causes hundreds of thousands of deaths worldwide, with about 1,500 of these in the United States.

The malaria-causing parasite, Plasmodium falciparum, is spread to people by the female Anopheles mosquito, which feeds on human blood. P. falciparum invades red blood cells, where it grows and multiplies. Eventually, the red blood cells burst, releasing into the bloodstream thousands of parasites that invade other red blood cells and continue the infection cycle.

Just how the human malaria parasite replicates itself inside red blood cells is, however, not well understood. Now a researcher at the University of California, Riverside has received a nearly $1.7 million four-year grant from the National Institute of Allergy and Infectious Diseases, the National Institutes of Health, to address this question.

"If we manage to understand how the parasite multiplies in the red blood cells, we will be able to develop more effective strategies for combating malaria," said Karine Le Roch, an assistant professor of cell biology and neuroscience and the grant's principal investigator. "The long term goal is to devise new drug strategies against this devastating disease."

Stefano Lonardi, an associate professor of computer science and engineering, will assist in the computational analysis of the massive amount of data produced by the sequencing instruments.

"The analysis pipeline is complex, but in the end we would like our software tools to generate a set of hypotheses of gene regulation for the malaria genome that Karine can test or validate in the lab," Lonardi said.

The grant will support one technician, one postdoctoral researcher and one Ph.D. graduate student. An expert in proteomics and mass spectrometry from the Stowers Institute, Kan., will collaborate.


'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Related biology news :

1. UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants
2. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist
3. UC Riverside scientist to explore how vegetation affects urban heat islands
4. UC Riverside rice geneticist receives high honor from US Department of Agriculture
5. UC Riverside biochemist to study how crops can increase protein production
6. UC Riverside researcher names lichen after President Barack Obama
7. UC Riverside professor receives top scientific honor
8. UC Riverside geneticist receives highest honor from Botanical Society of America
9. Public lecture at UC Riverside to discuss origin and fate of universe
10. UC Riverside student is 1 of only 5 persons selected for challenging Arctic expedition
11. UC Riverside research on barley genome gets boost from $1 million USDA grant
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UC Riverside cell biologist to investigate how malaria parasite multiplies in red blood cells
(Date:6/15/2016)... 2016 Transparency Market Research ... Market by Application Market - Global Industry Analysis Size Share ... the report, the  global gesture recognition market  was ... is estimated to grow at a CAGR of ... Increasing application of gesture recognition technology ...
(Date:6/7/2016)... June 7, 2016  Syngrafii Inc. and San ... relationship that includes integrating Syngrafii,s patented LongPen™ eSignature ... This collaboration will result in greater convenience for ... union, while maintaining existing document workflow and compliance ... ...
(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, ... after being treated for breast cancer benefitted from an injection of stem cells derived ... debilitating, frequent side effect of cancer treatment. , Lymphedema refers to the ...
(Date:6/23/2016)... -- On Wednesday, June 22, 2016, the NASDAQ ... Dow Jones Industrial Average edged 0.27% lower to finish at ... Stock-Callers.com has initiated coverage on the following equities: Infinity Pharmaceuticals ... NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ ... Learn more about these stocks by accessing their free trade ...
(Date:6/23/2016)... 22, 2016  Amgen (NASDAQ: AMGN ) ... QB3@953 life sciences incubator to accelerate the development ... laboratory space at QB3@953 was created to help high-potential ... for many early stage organizations - access to laboratory ... Amgen launched two "Amgen Golden Ticket" awards, providing each ...
Breaking Biology Technology: