Navigation Links
UC Irvine scientists find new way to sort stem cells
Date:12/20/2007

Irvine, Calif., Dec. 20, 2007 UC Irvine scientists have found a new way to sort stem cells that should be quicker, easier and more cost-effective than current methods. The technique could in the future expedite therapies for people with conditions ranging from brain and spinal cord damage to Alzheimers and Parkinsons diseases.

The method uses electrodes on a tiny, inch-long glass slide to sort cells by their electric charges and has been used in cancer research. The stem cell field suffers from a lack of tools for identifying and sorting cells. This important discovery could add a new tool to current sorting methods, which generally require expensive, bulky equipment.

For therapeutic purposes, we want stem cells to turn into specific cell types once they have been transplanted. The trick to doing this is identifying beforehand which cells will become the desired cell type, such as a neuron, said Lisa Flanagan, lead author of the study and a stem cell biologist at UCI. We have discovered a new, potentially better way to do this by focusing on the electric properties of the cells.

This study appears online Dec. 20 in the journal Stem Cells.

The technique used by the scientists, called dielectrophoresis, is based on the premise that different types of cells have different electric properties. Stem cells that are destined to become neurons, for example, have a different electric charge than stem cells that will become astrocytes, another type of brain cell. The scientists discovered that the cells react differently when electric fields are applied. At one frequency, a neuron will be attracted to an electrode but an astrocyte will not, and at a different frequency, an astrocyte will be attracted but a neuron will not.

Identifying and sorting stem cells is important when creating stem cell-based therapies. Without a purification process, stem cell transplantations can cause tumors or be rejected by the bodys immune sy
'/>"/>

Contact: Jennifer Fitzenberger
jfitzen@uci.edu
949-824-3969
University of California - Irvine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC Irvine receives $2.18M to explore nano advancements in DNA sequencing
2. UK scientists working to help cut ID theft
3. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
4. Comet probes reveal evidence of origin of life, scientists claim
5. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
6. Male elephants get photo IDs from scientists
7. Scientists retrace evolution with first atomic structure of an ancient protein
8. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
9. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
10. Clemson scientists shed light on molecules in living cells
11. Scientists tackle mystery mountain illness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... OXFORD, Conn. , July 7, 2015 NXT-ID, Inc. ... company focused on the growing mobile commerce market announces a revised ... airing this week. The commercial will air on CNBC in ... Los Angeles and San Francisco ... The commercial focuses on Wocket,s ability to replace all the ...
(Date:7/2/2015)... Sweden , July 2, 2015 ... sensors FPC1025, FPC1035, FPC1145 and FPC1155 from the distributor World ... one of FPC,s distributors in Asia . ... 2015. The sensors will be used by smartphone manufacturers in ... MSEK is included in the communicated revenue guidance of approximately ...
(Date:6/29/2015)... 2015 Research and Markets( ... "Latin America Biomedical Sensors Market - Growth, Trends & ... The Latin America Biomedical Sensors market is estimated at ... over the period 2014-2020 The near future ... genetic formulation of each individual. These sensors can be ...
Breaking Biology News(10 mins):Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2Latin America Biomedical Sensors Market Report 2015-2020 2
... revealed what may well be the first pervasive rule ... the Proceedings of the National Academy of Sciences researchers ... to become increasingly more complex. Looking back ... catalogue to the present day, the team investigated the ...
... not only smart, but they also wage a good ... studies have shown that plants can sense attacks by ... been known what happens between the pathogen attacks and ... revealed a very complex process that explains how plants ...
... holds three patents in the emerging field of nanotechnology ... the technology,s potential in materials science and medicine. ... a strong call for exploring potential environmental and health ... designing new materials with reduced hazard. The available data, ...
Cached Biology News:First 'rule' of evolution suggests that life is destined to become more complex 2Researcher discovers pathway plants use to fight back against pathogens 2Think green, UO's Hutchison says, to reduce nanotech hazards 2Think green, UO's Hutchison says, to reduce nanotech hazards 3
(Date:7/6/2015)...  Approximately 1% of the population inherits a common ... individuals are three times more likely to develop angina, ... the nation,s leading medical journals by researchers from the ... Photo - http://photos.prnewswire.com/prnh/20150706/230685 The ... (also known as "sixth disease") and occasional seizures in ...
(Date:7/6/2015)... Research and Markets ... the "Biotechnology for the Non-Biotechnologist" conference ... Non-Biotechnologist, ideal for non-Scientists and Scientists needing to ... of biotechnology. Ideal for Non-Scientists and ... techniques, and potential of biotechnology Why ...
(Date:7/6/2015)... ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE MKT: IMUC) ... Novella Clinical (Novella), to conduct the phase 3 ... glioblastoma. Novella is a full-service, global clinical research organization ... oncology companies. The ICT-107 phase 3 trial will include ... Europe and Canada , ...
(Date:7/3/2015)... 3, 2015 ... osoitteessa  http://www.openinnovationinscience.at Wienissä pidettävään ... Science" -jatkokoulutusohjelmaan 22.7.2015 asti.  ... tekemän, kansainvälisiä tutkijoita ja tiedemiehiä ... suurinta haastetta ovat kannustimien puute ...
Breaking Biology Technology:Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 2Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 3ImmunoCellular Therapeutics Establishes Agreement with Novella Clinical to Conduct ICT-107 Phase 3 Registration Trial in Glioblastoma 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 3
... management product is a hot holiday gift for 2008. Now available ... ... (Vocus) November 20, 2008 -- BodyMedia, Inc. , a pioneer ... GoWear® fit - a lifestyle and calorie management system ...
... Inc., http://www.microphage.com , today announced it has concluded its ... $11 million. Investors in,this round were a combination ... have come from private investors. , ... financing to complete the validation,and launch preparation of their ...
... Nov. 20 WWMR, Inc., the marketing research,leader ... "Most Appreciated Pain,Drug Company Survey". The top ... Endo Pharmaceuticals, according to the 100 pain clinic,physicians ... most noted for,their knowledgeable, respectful and informed sales ...
Cached Biology Technology:BodyMedia, Inc. Launches GowearFit, the First Direct-to-Consumer Lifestyle and Calorie Management System 2BodyMedia, Inc. Launches GowearFit, the First Direct-to-Consumer Lifestyle and Calorie Management System 3MicroPhage Closes Latest Financing 2WWMR Announces Pain Clinic Physicians' Most Appreciated Companies: Pfizer, Eli Lilly and Endo Pharmaceuticals 2WWMR Announces Pain Clinic Physicians' Most Appreciated Companies: Pfizer, Eli Lilly and Endo Pharmaceuticals 3
Sulfadimethoxine (CH-2027)...
... monoclonal [E12] to MAP1 Light Chain MAP1A ... physical interactions between microtubules and components of the ... heavy chain subunit and multiple light chain subunits. ... of the light chain subunits and can associate ...
... system is designed for multiple user laboratories ... for TLC applications. The MultiDoc-It is available ... enclosure provides a darkroom environment and protects ... Use image capture and enhancement , ...
Rabbit Polyclonal antibody to Perilipin Applications: This antibody is useful for Western blot anlaysis where a band at ~60 kDa is seen....
Biology Products: