Navigation Links
UC Davis team 'spikes' stem cells to generate myelin
Date:8/28/2013

(SACRAMENTO, Calif.) Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue. Findings from a team of UC Davis investigators have brought this dream a step closer by developing a method to generate functioning brain cells that produce myelin a fatty, insulating sheath essential to normal neural conduction.

"Our findings represent an important conceptual advance in stem cell research," said Wenbin Deng, principal investigator of the study and associate professor at the UC Davis Department of Biochemistry and Molecular Medicine. "We have bioengineered the first generation of myelin-producing cells with superior regenerative capacity."

The brain is made up predominantly of two cell types: neurons and glial cells. Neurons are regarded as responsible for thought and sensation. Glial cells surround, support and communicate with neurons, helping neurons process and transmit information using electrical and chemical signals. One type of glial cell the oligodendrocyte produces a sheath called myelin that provides support and insulation to neurons. Myelin, which has been compared to insulation around electrical wires that helps to prevent short circuits, is essential for normal neural conduction and brain function; well-recognized conditions involving defective myelin development or myelin loss include multiple sclerosis and leukodystrophies.

In this study, the UC Davis team first developed a novel protocol to efficiently induce embryonic stem cells (ESCs) to differentiate into oligodendroglial progenitor cells (OPCs), early cells that normally develop into oligodendrocytes. Although this has been successfully done by other researchers, the UC Davis method results in a purer population of OPCs, according to Deng, with fewer other cell types arising from their technique.

They next compared electrophysiological properties of the derived OPCs to naturally occurring OPCs. Th
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC Davis researchers discover molecular target for the bacterial infection brucellosis
2. UC Davis study deflates notion that pear-shaped bodies more healthy than apples
3. UC Davis researchers aid effort to sequence the complex wheat genome
4. UC Davis researchers develop new drug delivery system for bladder cancer using nanoparticles
5. UC Davis study finds that above-normal weight alone does not increase the short-term risk of death
6. UC Davis scientists find new role for P53 genetic mutation -- initiation of prostate cancer
7. Why are some cells more cancer prone?
8. Harvard Stem Cell researchers create cells that line blood vessels
9. UCI-led study reveals how SARS virus hijacks host cells
10. Fetal tissue-derived stem cells may be ideal source for repairing tissues and organs
11. Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has ... in India 2015-2019" report to their offering. ... this market is the adoption of multimodal biometric ... characteristic of an individual for verification and identification ...
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Wake Forest Baptist ... education building for its School of Medicine. Funding for ... larger capital campaign that will be publicly launched next ... be located in the former 60 series R.J. Reynolds ... Innovation Quarter. Construction will begin immediately with plans to ...
(Date:12/5/2014)... 4, 2014  Tute Genomics, a leader in cloud-based ... Series A1 funding led by UK-based Eurovestech. Peak Ventures ... the investment round. "We are at a ... next-generation sequencing and seeks new approaches for the diagnosis, ... , MD MBA, and CEO of Tute Genomics. "One ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3
... ozone as something in the upper atmosphere that protects ... level, however, ozone is a pollutant that damages crops, ... associate professor of crop sciences and USDA Agricultural Research ... threshold for damage is critical to understanding the current ...
... from a few tropical places in Asia, Africa, South and ... lighter build, thinner bodies and longer legs, better suited for ... of their legs, allowing them to better climb different surfaces, ... core area is the Amazon, from where most of the ...
... PROVIDENCE, R.I. [Brown University] Researchers from Brown University have ... can cause argyria, a rare condition in which patients, skin ... first conceptual model giving the whole picture of how one ... Brown and part of the research team. "What,s interesting here ...
Cached Biology News:Ozone's impact on soybean yield: Reducing future losses 2Ozone's impact on soybean yield: Reducing future losses 39 colorful and endangered tree-dwelling tarantulas discovered in Brazil 2How silver turns people blue 2How silver turns people blue 3
(Date:12/24/2014)... (PRWEB) December 23, 2014 ... series is designed to introduce cutting edge ... users and partners of platform upgrades. This ... benefits; empowering users in their quest to ... tools. , According to SoundConnect’s Marketing Manager, ...
(Date:12/24/2014)... 23, 2014 According to Ross Selinger, President ... of ITRA Global, the national office market continues to be ... This is evidenced by the third quarter’s surprising 3.9% GDP, ... Low energy costs have held inflation down and the Fed ... the housing market remaining soft. , This solid economic news ...
(Date:12/24/2014)... 23, 2014 Nashville Fertility Center announced ... treasurer for the American Society for Reproductive Medicine (ASRM), ... research in reproductive medicine. In his new role ... the executive board and will have a voice in ... has actively supported ASRM since 1984 when he joined ...
(Date:12/24/2014)... Diego, CA (PRWEB) December 23, 2014 ... where their Twitter followers can submit their #HolidayInTheLab ... themselves and their lab mates. , For those struggling ... lab mates, the Pipette.com Holiday in the Lab Contest ... Pipette.com Twitter followers to send pictures of ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2
... of a new way to tune and enhance thermal conductivity ... a given material gives engineers a new tool for ... a number of other powered devices. The finding was ... associate professor of mechanical engineering at Vanderbilt University, and published ...
... 14, 2011 /PRNewswire-Asia/ -- ShangPharma Corporation (NYSE: ... pharmaceutical and biotechnology research and development outsourcing company, today ... Annual Healthcare Conference, to be held in San Francisco ... Hui, founder and Chief Executive Officer of ShangPharma, and ...
... Elsevier, a world-leading provider of scientific, technical and medical ... Societies (FEBS) announced today the launch of FEBS ... is dedicated to publishing articles across the molecular and ... ,In launching this new journal, FEBS and Elsevier serve ...
Cached Biology Technology:New method for enhancing thermal conductivity could cool computer chips, lasers and other devices 2New method for enhancing thermal conductivity could cool computer chips, lasers and other devices 3Elsevier and Federation of Biochemical Societies Launch New Journal: FEBS Open Bio 2Elsevier and Federation of Biochemical Societies Launch New Journal: FEBS Open Bio 3
... EtBr Spin Columns provide a rapid and simple ... (100 bp to 10 kb) from stained agarose ... is excised from an agarose gel and loaded ... of the column are a series of membranes ...
... Kit enables efficient extraction of DNA fragments from 150 ... gels. The procedure uses GelMelt solution to dissolve the ... a silica membrane in a spin column format. After ... low-salt buffer. Each spin column can bind up to ...
When added to either StemSep CD4+ or CD8+ T Cell Enrichment cocktails, human HLA-DR TAC is designed to deplete human HLA-DR from samples to isolate resting CD4+ or CD8+ T cells....
... This microscope is described by end-users ... it incorporates the fundamentals of light microscopy ... and small footprint, it does not require ... in a busy lab environment. The DM-BA300 ...
Biology Products: