Navigation Links
UC Davis team 'spikes' stem cells to generate myelin
Date:8/28/2013

(SACRAMENTO, Calif.) Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue. Findings from a team of UC Davis investigators have brought this dream a step closer by developing a method to generate functioning brain cells that produce myelin a fatty, insulating sheath essential to normal neural conduction.

"Our findings represent an important conceptual advance in stem cell research," said Wenbin Deng, principal investigator of the study and associate professor at the UC Davis Department of Biochemistry and Molecular Medicine. "We have bioengineered the first generation of myelin-producing cells with superior regenerative capacity."

The brain is made up predominantly of two cell types: neurons and glial cells. Neurons are regarded as responsible for thought and sensation. Glial cells surround, support and communicate with neurons, helping neurons process and transmit information using electrical and chemical signals. One type of glial cell the oligodendrocyte produces a sheath called myelin that provides support and insulation to neurons. Myelin, which has been compared to insulation around electrical wires that helps to prevent short circuits, is essential for normal neural conduction and brain function; well-recognized conditions involving defective myelin development or myelin loss include multiple sclerosis and leukodystrophies.

In this study, the UC Davis team first developed a novel protocol to efficiently induce embryonic stem cells (ESCs) to differentiate into oligodendroglial progenitor cells (OPCs), early cells that normally develop into oligodendrocytes. Although this has been successfully done by other researchers, the UC Davis method results in a purer population of OPCs, according to Deng, with fewer other cell types arising from their technique.

They next compared electrophysiological properties of the derived OPCs to naturally occurring OPCs. Th
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC Davis researchers discover molecular target for the bacterial infection brucellosis
2. UC Davis study deflates notion that pear-shaped bodies more healthy than apples
3. UC Davis researchers aid effort to sequence the complex wheat genome
4. UC Davis researchers develop new drug delivery system for bladder cancer using nanoparticles
5. UC Davis study finds that above-normal weight alone does not increase the short-term risk of death
6. UC Davis scientists find new role for P53 genetic mutation -- initiation of prostate cancer
7. Why are some cells more cancer prone?
8. Harvard Stem Cell researchers create cells that line blood vessels
9. UCI-led study reveals how SARS virus hijacks host cells
10. Fetal tissue-derived stem cells may be ideal source for repairing tissues and organs
11. Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... SM announced today its completion of a Good ... current U.S. Food and Drug Administration (FDA) regulations. This ... smart phone application trials utilizing the highest principles for ... determined to improve global healthcare access, quality, and delivery ...
(Date:12/17/2014)... , Dec. 16, 2014 Research and Markets ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in this market ... applications. Chemical sensors help in recording of patient data ...
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report to their ... Facial recognition is a technology used for the ... facial feature of a person such as nose, jaw ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... the tropical ocean coastlines, are far more important to ... the foul-smelling muddy forests may not have the scientific ... of researchers has noted that the woody coastline-dwelling plants ... carbon that is supplied to the global ocean from ...
... blubber falls below average levels may be at higher risk ... enough fat in their diets later on, according to a ... at Experimental Biology 2006. , The study found that harbor ... continued to gain weight and grow regardless of whether the ...
... transplantation performed in France spread around the world, plastic ... first full facial transplantation a reality. , In the ... surgeons demonstrated how to successfully complete a full facial ... the March issue of Plastic and Reconstructive Surgery® (PRS), ...
Cached Biology News:The critical importance of mangroves to ocean life 2Alaska seal pup diet may hold key to decline of population 2Alaska seal pup diet may hold key to decline of population 3Alaska seal pup diet may hold key to decline of population 4Plastic surgeons countdown first full facial transplantation 2
(Date:12/24/2014)...   BioLife Solutions , Inc. (NASDAQ: BLFS ), ... hypothermic storage and cryopreservation freeze media ... tissues  ("BioLife" or the "Company"), today announced that it will ... 2015 (the "Annual Meeting"). Because the expected date ...
(Date:12/24/2014)... Earlier this year in a June 24 international conference presentation, ... Technology Center, LLC ( ASCTC ) focused attention on an ... stem cells. His title “Asymmetric Self-Renewal by Distributed Stem ... the essence of his message to congress participants. He ...
(Date:12/24/2014)... 2014 According to Ross Selinger, President of ... ITRA Global, the national office market continues to be strong, ... is evidenced by the third quarter’s surprising 3.9% GDP, unemployment ... energy costs have held inflation down and the Fed is ...
(Date:12/24/2014)... 2014 The report expects global cell isolation ... also provides a carefully analyzed data about the vital drivers, ... Full Copy of Report @ http://bit.ly/1yUxy0T , According ... keep witnessing growth at an impressive CAGR during near future. ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3
... -- The Nano Science and Technology Institute (NSTI), today ... place May 3-7, 2009 at the George R. Brown Convention ... the largest and most prominent Nanotechnology event is expected to ... Bio technology executives, who will gather to promote advanced research ...
... Allscripts announced today that,Tully-Wihr Company, in conjunction ... to resell the web-based Allscripts MyWay(TM) Electronic,Health Record ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20081013/AQM041LOGO ... 1906, Tully-Wihr has been building forms management solutions,for ...
... BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX ) today announced ... Dr. William P. Sheridan, Chief Medical Officer of BioCryst, will ... Healthcare Conference on Thursday, January 15, 2009 at 7:30 a.m. ... 2009 in San Francisco.A link to a live audio Web ...
Cached Biology Technology:NSTI Announces the 12th Annual Nanotech Conference & Expo 2009 May 3-7, at the George R. Brown Convention Center in Houston, Texas 2NSTI Announces the 12th Annual Nanotech Conference & Expo 2009 May 3-7, at the George R. Brown Convention Center in Houston, Texas 3NSTI Announces the 12th Annual Nanotech Conference & Expo 2009 May 3-7, at the George R. Brown Convention Center in Houston, Texas 4Tully-Wihr Company Selects Web-Based Allscripts Electronic Health Record for 100 Northern California Physicians 2Tully-Wihr Company Selects Web-Based Allscripts Electronic Health Record for 100 Northern California Physicians 3Tully-Wihr Company Selects Web-Based Allscripts Electronic Health Record for 100 Northern California Physicians 4Tully-Wihr Company Selects Web-Based Allscripts Electronic Health Record for 100 Northern California Physicians 5BioCryst to Present at the J.P. Morgan 27th Annual Healthcare Conference 2BioCryst to Present at the J.P. Morgan 27th Annual Healthcare Conference 3