Navigation Links
UC Davis researchers find disease-causing fat cells in those with metabolic syndrome
Date:8/24/2011

(SACRAMENTO, Calif.) UC Davis Health System researchers have discovered biological indicators that help explain why some obese people develop chronic diseases such as diabetes and heart disease, and others do not.

The researchers took a novel approach of looking specifically at the body fat of people with metabolic syndrome -- a condition characterized by increased blood pressure, high-fasting blood-sugar levels, excess abdominal fat and abnormal cholesterol levels. They found the fat cells released biomarkers associated with insulin resistance and chronic inflammation, conditions often leading to diabetes and cardiovascular disease.

"Our study shows that not all obesity is the same and some body fat may actually be toxic," said Ishwarlal Jialal, UC Davis professor of endocrinology, diabetes and metabolism and senior author of the article, "Adipose Tissue Dysregulation in Patients with Metabolic Syndrome," published online today in the Journal of Clinical Endocrinology & Metabolism. "We have shown that the dysfunction in the fat of people with metabolic syndrome is more than can be explained by obesity. It tells us that metabolic syndrome is a high-risk condition for people who are obese."

While previous studies using circulating blood have found some of these biomarkers in people with metabolic syndrome, the current study is the first to pinpoint fat as a contributing source of these markers. The study is also unique in that it involved patients newly diagnosed with metabolic syndrome who had not yet developed diabetes or cardiovascular disease. Researchers compared fat from study subjects to fat from people who were also obese, but did not have metabolic syndrome.

"This drives home the point that clearly metabolic syndrome is high-risk for obesity and needs to be treated seriously," said Jialal, who directs the UC Davis Laboratory for Atherosclerosis and Metabolic Research.

The Centers for Disease Co
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC Davis chemical ecologist wins major award
2. UC Davis researchers discover a key to aggressive breast cancer
3. UC Davis researchers discover Achilles heel in pancreatic cancer
4. UC Davis researchers exploring gene therapy to fight AIDS
5. UC Davis team refines cancer treatments to reduce potential nerve damage
6. UC Davis discovery offers hope for treating kidney cancer
7. UC Davis researchers find molecule that targets brain tumors
8. UC Davis research shows that newly discovered drug reduces heart enlargement
9. UC Davis bench-to-bedside research: Promising treatment in clinical trials
10. UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs
11. UC Davis launches One Health care for wild mountain gorillas and human neighbors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... , Aug. 5, 2015 The biosensors market ... in applications, penetration into newer sectors, and development of ... global biosensors space has seen the entry of multiple ... so far. (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ) ... Analysis of the Global Biosensors Market ( ...
(Date:8/3/2015)... , Aug. 3, 2015 Synaptics, Inc. (Nasdaq: ... solutions, today announced that members of the executive management ... Pacific Crest Global Technology Leadership Forum on Tuesday, August ... will be held at the Sonnenalp Resort in ... presentation may include forward-looking information. An audio webcast of ...
(Date:7/31/2015)... de 2015 A 10 a. Conferência ... pela BGI de 22-25 de outubro de 2015, em ... conferência está celebrando seu 10 o. aniversário este ano. ... uma das reuniões mais influentes do mundo no ramo ... entusiastas e prazerosos. A ICG-10 se ...
Breaking Biology News(10 mins):Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3
... work, home or elsewhere results in a disproportionate rise ... University of Nottingham researchers have found. , A new ... Heart Association, measured the level of cotinine in participants' ... to second-hand smoke. Cotinine is the major metabolite of ...
... Trek: The Next Generation," Geordi La Forge is a ... special implants in his eyes. While the Star Trek ... the 21st century may not have to wait that ... a University of Missouri-Columbia veterinary ophthalmologist, has been working ...
... with a knowledge of the properties and actions of enzymes, ... anti-cancer drugs originally isolated from blue-green algae. , This ... of the promising drugs for use in clinical trials. ... January issue of the journal ACS Chemical Biology, a scientific ...
Cached Biology News:Indicators for risk of heart disease are higher in passive smokers 2Indicators for risk of heart disease are higher in passive smokers 3MU researcher placing eye implants in cats to help humans see 2Turning green gunk to gold, anti-cancer gold 2
(Date:9/2/2015)... Israel , September 2, 2015 ... announced the intent of the National Institute of Allergy and ... Health (NIH) within the Department of Health and Human Services ... held in the United States in ... BiondVax,s universal flu vaccine candidate, Multimeric-001 (M-001), as a primer ...
(Date:9/2/2015)... California (PRWEB) , ... September 02, 2015 , ... ... a critical demand to aid high-risk surgeries. From vital sign monitoring in ICU ... by Intel technology enables surgeon to make real-time clinical decisions with simultaneous access ...
(Date:9/2/2015)... ... 2015 , ... Temarry Recycling's new $100,000 waste to energy ... and continue to contribute to the sustainability of our natural resources. , Waste ... has been operating at their Mexico facility, Recicladora Temarry, for the last 7 ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... life science research, today unveiled Genedata Screener ® version 13.0 at ELRIG ... screening brings to market a rich set of new capabilities. Screener now supports ...
Breaking Biology Technology:BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 2BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 3Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 2Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 3Temarry Recycling’s New $100,000 Waste to Energy Renovation 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 3New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 4
... Wilson , an 18-year GE veteran, was promoted to president ... May to replace Gregory Lucier, who left to become CEO ... most of GE Medical's monitoring systems . , ,It's a ... growth opportunity (GE Medical is about $9 billion and produced ...
... - With Sony set to take over Sonic Foundrys desktop ... go from here? Two words: Mediasite Live. , ,Sonic ... audio conferencing market by enhancing web conferencing with Mediasite Live. ... great opportunity for the company to go forward because there ...
... employee scheduling and management products. The company was the ... Suite Scheduler, a former nurse manager frustrated with the ... facility. , ,Suite Scheduler products are able to improve ... of the time to create and manage employee schedules ...
Cached Biology Technology:CEO Wilson Defines GE's Health-IT Customer 2CEO Wilson Defines GE's Health-IT Customer 3CEO Wilson Defines GE's Health-IT Customer 4Sonic Foundry: What's Next? 2Scheduling made easy with Suite Scheduler 2Scheduling made easy with Suite Scheduler 3
Zebrafish Ephrin-B2 Biotinylated Affinity Purified PAb...
...
Donor Goat Serum...
GeneRacer is an advanced RACE (rapid amplification of cDNA ends) technique that improves the efficiency of amplifying full-length 5' and 3' cDNA ends. With the GeneRacer Kit you can:...
Biology Products: