Navigation Links
UC Davis researchers find disease-causing fat cells in those with metabolic syndrome
Date:8/24/2011

(SACRAMENTO, Calif.) UC Davis Health System researchers have discovered biological indicators that help explain why some obese people develop chronic diseases such as diabetes and heart disease, and others do not.

The researchers took a novel approach of looking specifically at the body fat of people with metabolic syndrome -- a condition characterized by increased blood pressure, high-fasting blood-sugar levels, excess abdominal fat and abnormal cholesterol levels. They found the fat cells released biomarkers associated with insulin resistance and chronic inflammation, conditions often leading to diabetes and cardiovascular disease.

"Our study shows that not all obesity is the same and some body fat may actually be toxic," said Ishwarlal Jialal, UC Davis professor of endocrinology, diabetes and metabolism and senior author of the article, "Adipose Tissue Dysregulation in Patients with Metabolic Syndrome," published online today in the Journal of Clinical Endocrinology & Metabolism. "We have shown that the dysfunction in the fat of people with metabolic syndrome is more than can be explained by obesity. It tells us that metabolic syndrome is a high-risk condition for people who are obese."

While previous studies using circulating blood have found some of these biomarkers in people with metabolic syndrome, the current study is the first to pinpoint fat as a contributing source of these markers. The study is also unique in that it involved patients newly diagnosed with metabolic syndrome who had not yet developed diabetes or cardiovascular disease. Researchers compared fat from study subjects to fat from people who were also obese, but did not have metabolic syndrome.

"This drives home the point that clearly metabolic syndrome is high-risk for obesity and needs to be treated seriously," said Jialal, who directs the UC Davis Laboratory for Atherosclerosis and Metabolic Research.

The Centers for Disease Co
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC Davis chemical ecologist wins major award
2. UC Davis researchers discover a key to aggressive breast cancer
3. UC Davis researchers discover Achilles heel in pancreatic cancer
4. UC Davis researchers exploring gene therapy to fight AIDS
5. UC Davis team refines cancer treatments to reduce potential nerve damage
6. UC Davis discovery offers hope for treating kidney cancer
7. UC Davis researchers find molecule that targets brain tumors
8. UC Davis research shows that newly discovered drug reduces heart enlargement
9. UC Davis bench-to-bedside research: Promising treatment in clinical trials
10. UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs
11. UC Davis launches One Health care for wild mountain gorillas and human neighbors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2015)... , July 07, 2015 ... the addition of the "Biometrics for Banking; ... 2015-2020" report to their offering. ... contributor to this growth and the forecast is ... in revenue for companies involved in delivering biometric ...
(Date:7/9/2015)... 9, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced a new Match-in-Sensor™ ... hardware encapsulated fingerprint sensor and matching solution. ... literally off the grid, isolating fingerprint image ... the fingerprint sensor to provide ultimate protection ...
(Date:7/8/2015)... NEW YORK , July 8, 2015  BD ... announced BD & Guidepoint Mentor, a new ... to Guidepoint,s expert network services. BD ... technologies to improve healthcare delivery and outcomes and, with ... start-up entrepreneur will be able to directly engage with ...
Breaking Biology News(10 mins):Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3
... 9, 2010 USDA Forest Service researchers found that ... habitats, is strong in the Sierra Nevada yellow-legged frog. ... climate and introduced non-native trout are negatively impacting the ... of its historic localities, and will further stress frogs ...
... in 1906, the German physician Paul Ehrlich coined the term ... medical treatment. Magic bullets, also called silver bullets, because ... supernatural creatures, remain the goal of drug development efforts today. ... Louis is currently working on a magic bullet for cancer, ...
... hydrosurgery system to help physicians better manage excessive bleeding during surgery., ... Oberdier, a Ph.D. candidate in biomedical engineering at ... clear excess blood and control bleeding during critical stages involving brain operations., ... "We are creating a device that will ...
Cached Biology News:Sierra Nevada yellow-legged frog's site fidelity may lead to further decline 2A golden bullet for cancer 2A golden bullet for cancer 3A golden bullet for cancer 4A golden bullet for cancer 5
(Date:7/29/2015)... +14% CER / 20% of sales) led the regional performance in the second ... well as solid contributions from Korea, India and ... East / Africa (Q2 2015: +3% CER ... Turkey and the United Kingdom . The ... HPV sales, on demand across all customer classes. The top seven emerging markets ...
(Date:7/29/2015)... SAN FRANCISCO , July 29, 2015 /PRNewswire/ ... trialling mobile molecular testing for applications in food ... Ubiquitome,s hand-held, battery powered real-time PCR device, the ... the farm right through to the supermarket shelf ... world. This includes involvement in animal disease control ...
(Date:7/29/2015)... ... 29, 2015 , ... Brady (NYSE:BRC), a global leader in ... To align chemical container labeling with OSHA’s updated Hazard Communication (HazCom) Standard and ... example of an accurate label, and pictogram uses and meanings. , “With changes ...
(Date:7/29/2015)... SAN DIEGO , July 29, 2015  Pfenex ... quarter 2015 financial results will be released on Thursday, ... 8:30 am Eastern Time, Pfenex management will host a ... a business update.  A press release outlining the financial ... to the call. Please call 1-866-376-8058 (US) ...
Breaking Biology Technology:QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2Brady Announces a New GHS Label Guide 2Pfenex To Report Second Quarter 2015 Results and Provide Business Update on Thursday, August 13, 2015 2
... Wisconsin-born leader in the World Health Organization has laid ... and develop an antidote to nicotine addiction, and the ... , ,Tom Loftus, the former U.S. ambassador to Norway ... a sobering global perspective to last weeks Wisconsin Life ...
... Madison, Wis. - Companies looking to thrive in an ... Wisconsin Public Radio reports on one rather unusual method: speed-networking, ... Technology Network... Listen to this story now using RealPlayer ... its the fast that eat the slow. That phrase was ...
... CHICAGO This column isnt just for Midwestern technology job seekers. ... so hard on job seekers here? Because so many of us ... More than that, it's because theres so much to say on ... know. So many angles to try. And, for better or worse, ...
Cached Biology Technology:AIDS and tobacco are worldwide killers: Is bioscience doing enough to stop them? 2Looking to be Competitive? Try Speed Networking 2Its Your Midwest Technology Wake, Stupid 2Its Your Midwest Technology Wake, Stupid 3
... 5 Fluorescein 6-Fam, Hex, Tet ... Fluorescein Tamra Black Hole Quenchers ... Hex, Tet Tamra, Joe 3 ... Institute, New York Double labelled probes are ...
... The flexible and easy ... used to control all members ... family. It features a clear ... visual assay setup, user-friendly and ...
... Recombinant Enterokinase (rEK) is a highly ... bovine enterokinase, a serine protease which recognizes ... enzyme (AspAspAspAspLys?) and has similar enzymatic activity ... coli and purified to yield the highest ...
Roll of Mesh 5m x 25cm...
Biology Products: