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UC Davis Purchases Irys System From BioNano Genomics To Advance Genome Mapping And Assembly Of Wheat Relative
Date:1/13/2014

SAN DIEGO, Jan. 13, 2014 /PRNewswire/ -- BioNano Genomics announced today the purchase of an IrysSystem by UC Davis to assist, among other projects, in completing the genome assembly of Aegilops tauschii, one of three progenitors of today's bread wheat. The team of researchers at UC Davis, led by Dr. Jan Dvorak, will use the Irys System in their workflow as they determine the sequence, location, and orientation of all genes and transposable elements of the A. tauschii genome.  This information will be used to advance the assembly and analysis of the wheat genome sequence, which is known to be five times larger and significantly more complex than the human genome.

"Among the world's essential crops for human and animal food, the wheat genome has yet to be fully realized because of its complexity," said Erik Holmlin, president and CEO of BioNano Genomics. "The UC Davis team's research with A. tauschii will help determine how wheat genome is organized and contribute to the large international effort to decode the genome of one of the world's most important food crops."

"To date, very few high-quality assemblies are available for large and complex genomes, like wheat, because we have inaccurate, low-resolution physical maps on which to arrange DNA sequence information," stated Han Cao, Ph.D., founder and chief scientific officer of BioNano Genomics. "The Irys System provides a high-resolution genome map upon which DNA sequences can quickly and accurately be organized."

Ancestor Gives Clues to Today's Wheat

Bread wheat (Triticum aestivum L.) is a hexaploid species containing three different ancestral genomes (designated A, B, and D), each of which has seven pairs of chromosomes. In addition, approximately 90 percent of the
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