Navigation Links
UBC researchers invent new drug delivery device to treat diabetes-related vision loss
Date:6/30/2011

zing water out of a flexible bottle.

In a series of lab tests, the UBC researchers loaded the implantable device with the drug docetaxel and triggered the drug release at a dosage suitable for treating diabetic retinopathy. They found that the implantable device kept its integrity with negligible leakage over 35 days.

They also monitored the drug's biological effectiveness over a given period, testing it against two types of cultured cancer cells, including those found in the prostate. They found that they were able to achieve reliable release rates.

"The docetaxel retained its pharmacological efficacy for more than two months in the device and was able to kill off the cancer cells," says Pirmoradi.

The UBC device offers improvements upon existing implantable devices for drug delivery, says Chiao.

"Technologies available now are either battery operated and are too large for treating the eye, or they rely on diffusion, which means drug release rates cannot be stopped once the device is implanted a problem when patients' conditions change."

Pirmoradi says it will be several years before the UBC device is ready for patient use. "There's a lot of work ahead of us in terms of biocompatibility and performance optimization."

The team is also working to pinpoint all the possible medical applications for their device so that they can tailor the mechanical design to particular diseases.


'/>"/>

Contact: Lorraine Chan
lorraine.chan@ubc.ca
604-822-2644
University of British Columbia
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... 2014A new ovoid structure discovered in the Nakhla Martian ... variety of minerals, and shows evidence of undergoing a ... the permafrost and mixing of surface and subsurface fluids. ... analytical studies to determine the origin of this new ... ovoid formed, point to the most likely conclusion, and ...
(Date:8/19/2014)... treat pain, but its effect on pain following ... recent study reported on the Neural Regeneration ... models of an avulsion injury to the left ... pain) were given electroacupuncture stimulation at bilateral Quchi ... After electroacupuncture therapy, chronic neuropathic pain in the ...
(Date:8/19/2014)... , August 19, 2014 Smart ... Digital Wallet Choices as latest developments, ad campaigns and ... (NASDAQ: EBAY ), Amazon.com Inc. (NASDAQ: ... ), Google Inc. (NASDAQ: GOOG ) and ... NXTD) a biometric authentication company focused on the growing ...
Breaking Biology News(10 mins):Life on Mars? Implications of a newly discovered mineral-rich structure 2Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 2Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 3Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 4Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 5Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 6Digital Wallet Choices; PayPal, Google Wallet, Apple Passbook - and Now Wocket Smart Wallet : Who Addresses Issues of Security? 7
... COLUMBUS, Ohio Insulin resistance, the hallmark of type ... is paradoxically also an apparent contributor to muscle wasting ... to new research. And in an animal study, ... progression of muscle wasting and fat loss, the main ...
... Biological Sciences Research Council (BBSRC)-funded research, published this week ... discovered molecules that could confuse insects, ability to detect ... could reduce damage to crops by insect pests and ... Hooper of Rothamsted Research, an institute of BBSRC said: ...
... highly complex, research to understand how people fight infection ... simpler organisms. Zebrafish are becoming an important model for ... manipulated and many fundamental processes between zebrafish and humans ... highly amenable to drug screening assays. The functional similarity ...
Cached Biology News:Diabetes drug shows promise in fighting lethal cancer complication 2Diabetes drug shows promise in fighting lethal cancer complication 3Scientists discover how to send insects off the scent of crops 2Fish fend off invading germs with an initial response similar to the one found in people 2
(Date:8/18/2014)... NYElectronic devices with unprecedented efficiency and data ... that use built-in electric polarizations to read ... inside most popular data-driven technology. But ferroelectrics ... blocks, including a curious habit of "forgetting" ... the U.S. Department of Energy,s Brookhaven National ...
(Date:8/18/2014)... 18, 2014 Dyadic International, Inc. ("Dyadic") ... and proprietary technologies are used to develop, manufacture ... bioenergy, bio-based chemical, biopharmaceutical and industrial enzyme industries, ... Statement on Form 10 with the U.S. Securities ... - http://photos.prnewswire.com/prnh/20110621/CL06708LOGO The ...
(Date:8/16/2014)... physicists have found a way to make atomic-force microscope ... forces as small as the weight of an individual ... Australian National University (ANU), hinges on using laser beams ... Celsius. , "The level of sensitivity achieved after cooling ... of a large virus that is 100 billion times ...
(Date:8/15/2014)...  Two 5-foot-5 superbug-slaying machines were deployed from ... to JFK Hospital and ELWA Hospital in ... , where they will aid in the fight against ... - http://photos.prnewswire.com/prnh/20140814/136426 The devices, ... environments where Ebola patients are being treated. TRU-D is ...
Breaking Biology Technology:Promising ferroelectric materials suffer from unexpected electric polarizations 2Promising ferroelectric materials suffer from unexpected electric polarizations 3Promising ferroelectric materials suffer from unexpected electric polarizations 4Dyadic International Files Form 10 Registration Statement 2Dyadic International Files Form 10 Registration Statement 3Dyadic International Files Form 10 Registration Statement 4Laser makes microscopes way cooler 2Germ-Killing Robots Deployed to the Republic of Liberia To Aid in Battle Against Ebola Virus 2Germ-Killing Robots Deployed to the Republic of Liberia To Aid in Battle Against Ebola Virus 3
... with antibodies that react to the sample. The test result can ... either does or does not appear depending on the sample ... consumers. It is also possible to print instructional images or text, ... can be used to test quickly and easily for the presence ...
... producing nanoscopic crystals of a pharmaceutical product can allow the ... drug is not soluble in water. Research suggests that ... the pharmaceutical industry dissolve only very weakly in water, if ... drugs as it means they are not effective if taken ...
... and interact.  That,s the marketing mantra at ... creator of the best-selling children,s FireFly™ ... of the Binaca™ brand.   ...   http://www.newscom.com/cgi-bin/prnh/20101006/LA77977LOGO ) The company has ...
Cached Biology Technology:VTT printed hemoglobin test on paper 2Nano drugs 2A 'Fresh' Approach to Marketing: Dr. Freshâ„¢, Inc. Goes Guerilla With Internet-Based Campaigns 2
... Sequencing Quality 96 Well ... BAC template preparation from 1.5ml ... suitable for automated fluorescent sequencing ... DNA; Utilizes ProPrep strategy which ...
...
TLN2 Antibody...
Olig2 Immunogen: Synthetic peptide from rat. Available Date: 9-19-2006...
Biology Products: