Navigation Links
UBC researchers design new biomaterial that mimics muscle elasticity
Date:5/5/2010

University of British Columbia researchers have cast artificial proteins into a new solid biomaterial that very closely mimics the elasticity of muscle.

The approach, detailed in the current issue of the journal Nature, opens new avenues to creating solid biomaterials from smaller engineered proteins, and has potential applications in material sciences and tissue engineering.

"There are obvious long-term implications for tissue engineers," says Hongbin Li, associate professor in the Dept. of Chemistry. "But at a fundamental level, we've learned that the mechanical properties we engineer into the individual proteins that make up this biomaterial can be translated into useful mechanical properties at the larger scale."

Li, Canada Research Chair in Molecular Nanoscience and Protein Engineering, and UBC colleague John Gosline, professor in the Dept. of Zoology, engineered the artificial proteins to mimic the molecular structure of titin.

Titin also known as connectin is a giant protein that plays a vital role in the passive elasticity of muscle. The engineered version-which resembles a chain of beads-is roughly 100 times smaller that titin.

The resulting rubber-like biomaterial showed high resilience at low strain and was tough at high strain features that make up the elastic properties of muscles.

"A hallmark of titin-like proteins is that they unfold under a stretching force to dissipate energy and prevent damage to tissues by over-stretching," says Gosline. "We've been able to replicate one of the more unique characteristics exhibited by muscle tissues, but not all of them."

The mechanical properties of these biomaterials can be fine-tuned, providing the opportunity to develop biomaterials that exhibit a wide range of useful properties including mimicking different types of muscles. The material is also fully hydrated and biodegradable.


'/>"/>

Contact: Chris Balma
balma@science.ubc.ca
604-822-5082
University of British Columbia
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/16/2015)... HANOVER, Germany , March 16, 2015 /PRNewswire/ ... DERMALOG Identification Systems GmbH will present groundbreaking innovations ... Hanover, Germany . ... DERMALOG,s latest biometric innovation is well at ... the next generation e-gate made in ...
(Date:3/12/2015)... , March 12, 2015 The mascots ... Brenner Children,s Hospital, part of Wake Forest Baptist Medical ... initiative for the 2015 ACC Men,s Basketball Tournament. Young ... with them and getting their autographs. Brenner ... Baptist. It is the only children,s hospital in northwest ...
(Date:3/12/2015)... Calif. , March 12, 2015 WHEN:Tuesday, ... Complimentary Registration here: http://bit.ly/1G7Os0L . SPEAKERS: , ... Aravind SeshagiriPhoto - http://photos.prnewswire.com/prnh/20150311/181111 ... order to compete in several different markets and ... is currently witnessing an uptrend. ...
Breaking Biology News(10 mins):DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3
... drugs of abuse decrease the generation of new neurons ... this process, called neurogenesis, had not been clear. , ... advance of print publication of the November issue of ... from University of Saskatchewan show that a potent and ...
... a type of blue-green algae known as Nostoc, shows promise ... other neurodegenerative diseases, according to an in vitro study by ... time that a potent agent against Alzheimer's has been isolated ... published in the Dec. 26 issue of the Journal ...
... that has been used to track the source of ... may have some new uses: detecting rapidly growing cancers ... known as "stable isotope ratio mass spectrometry," can determine ... or isotopes of an element in the substance ?such ...
Cached Biology News:Natural compound from 'pond scum' shows potential activity against Alzheimer's 2War on terror meets war on cancer 2War on terror meets war on cancer 3War on terror meets war on cancer 4War on terror meets war on cancer 5War on terror meets war on cancer 6
(Date:4/1/2015)... Holomic is introducing the HRDR-400, the ... and fluorescent rapid tests with one device. , ... readers and is already selling its HRDR-200 chromatographic and ... of its kind offering for manufacturers and end-users that ... Neven Karlovac, CEO of Holomic LLC, commented, "We are ...
(Date:4/1/2015)... Earlier this year, A.J. O’Connor Associates ... association that represents research-based life science organizations in New ... AJO’s Vice President of Business Development & Executive Coach, ... that attracted over 750 attendees. , In one ... old cancer survivor shared his moving story of how, ...
(Date:3/31/2015)... Fla. , March 31, 2015  Biotest Pharmaceuticals ... is pleased to announce the addition of its newest ... Suite 205 Conway, Arkansas . The ... doors for business on March 26 th 2015 ... centers to eighteen. "This facility represents ...
(Date:3/31/2015)... PA (PRWEB) March 31, 2015 Pittcon ... and Applied Spectroscopy, ended on March 12, in New ... at $21 million as estimated by the New Orleans ... more than 14,200 conferees and exhibitor personnel. Those ... of the conferee number. For the third year, the ...
Breaking Biology Technology:Holomic to Introduce the First Dual, Chromatographic and Fluorescent Rapid Test Reader, the HRDR-400 2HR Consulting Firm, A.J. O'Connor Associates Joins BioNJ – The Vibrant 400 Member Strong Life Sciences Industry Association - and Attends its Annual Dinner 2Biotest Pharmaceuticals Corporation Announces the Opening of its Newest Plasma Collection Facility in Conway, Arkansas 2Pittcon 2015 Hits the Big Easy in a Big Way 2Pittcon 2015 Hits the Big Easy in a Big Way 3Pittcon 2015 Hits the Big Easy in a Big Way 4
... Mass., March 3 ETEX Corporation, an advanced,biomaterials ... a supply,agreement with LifeNet Health, Inc., Under ... Bone Matrix (DBM) powder to be mixed with ... substitute material called,EquivaBone(TM). ETEX will manufacture EquivaBone(TM) in ...
... Md., March 3 Iomai Corporation,(Nasdaq: IOMI ) ... 2007 financial results before the markets open and hold ... clinical progress,on Thursday, March 6, 2008 at 1:30 p.m. ... the live conference call on Thursday, March 6 at ...
... - BIKAM,pioneers in the discovery and development ... degenerative eye diseases and ocular disorders and,Dalton ... worldwide,collaboration and agreement to discover and develop ... Dalton Medicinal Chemistry will utilize their proprietary ...
Cached Biology Technology:ETEX and LifeNet Health, Inc. Enter Agreement 2Iomai to Announce Fourth Quarter and Year-End 2007 Financial Results and Host Webcast on Thursday, March 6 2BIKAM and Dalton Medicinal Chemistry Sign Collaborative Research Agreement 2
... SAGE (serial analysis of gene ... expression analysis. Expression profiles generated ... to detect low-abundance transcripts making ... genes. The I-SAGE Kit is ...
Sheep Serum US Origin...
... ultimate in utility and flexibility press-to-seal silicone ... needs of the researcher. They are available ... as sheet material that can be easily ... are autoclavable and non-cytotoxic and can be ...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
Biology Products: