Navigation Links
UA pharmacy research shows prescribers miss potentially dangerous drug pairs
Date:7/13/2009

Tucson, Ariz.Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.

These findings raise concern because of the high number of drugs Americans take: an average of 2.3 medications is prescribed during each physician office visit.

A synopsis of the research was published in May Research Activities (http://www.ahrq.gov/research/may09/0509RA4.htm), a digest of research findings intended to contribute to the national policymaking process.

The researchers, led by Daniel Malone, PhD, professor at the UA College of Pharmacy, mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians' assistants and nurse practitioners.

Recipients were asked to classify 14 drug pairs as "contraindicated," "may be used together but with monitoring" or "no interaction." Respondents could also state that they were "not sure."

For the drug pairs, one commonly prescribed medication was matched with another commonly prescribed medication.

The 950 respondents classified 42.7 percent of all drug combinations correctly.

Of the 14 drug pairs presented, four of them were contraindicated, meaning they should not be used together. A majority of prescribers correctly identified only one of the four pairs as contraindicated.

Moreover, for half of the 14 drug pairs, more than one-third of the respondents answered that they were "not sure," and two of these drug pairs were contraindicated.

"The study found a very low rate of recognition of these particular interactions," says Malone, "and some of these interactions are very common."

Use of several of the contraindicated drug pairs could be dangerous. For example, taking sildenafil (Viagra) and nitrates, such as isosorbide mononitrate, can be life-threatening.

According to Malone, the research indicates that health professional programs are not doing enough to teach students about potential drug-drug interactions. Consequently, patients should be sure to tell their pharmacist of all the medications they are taking.


'/>"/>

Contact: Karin Lorentzen
lorentzen@pharmacy.arizona.edu
520-626-3725
University of Arizona, College of Pharmacy
Source:Eurekalert  

Related biology news :

1. Research shows skeleton to be endocrine organ
2. Newly created cancer stem cells could aid breast cancer research
3. Dominant cholesterol-metabolism ideas challenged by new research
4. Researchers identify proteins involved in new neurodegenerative syndrome
5. Texas researchers and educators head for Antarctica
6. MGH researchers describe new way to identify, evolve novel enzymes
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
9. U of MN researchers discover noninvasive diagnostic tool for brain diseases
10. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
11. Story ideas from the Journal of Lipid Research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UA pharmacy research shows prescribers miss potentially dangerous drug pairs
(Date:6/16/2016)... June 16, 2016 The ... expected to reach USD 1.83 billion by 2024, ... Research, Inc. Technological proliferation and increasing demand in ... expected to drive the market growth. ... The development of advanced multimodal techniques for ...
(Date:6/9/2016)... , June 9, 2016  Perkotek an innovation leader in attendance control systems ... seamlessly log work hours, for employers to make sure the right employees are actually ... http://photos.prnewswire.com/prnh/20160609/377486LOGO ... ... ...
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. ... a business relationship that includes integrating Syngrafii,s patented ... branch project. This collaboration will result in greater ... the credit union, while maintaining existing document workflow ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge ... envision new ways to harness living systems and biotechnology, ... Art (MoMA) in New York City ... 130 participating students, showcased projects at MoMA,s Celeste Bartos ... Paola Antonelli , MoMA,s senior curator of architecture and ...
Breaking Biology Technology: