Navigation Links
UA pharmacy research shows prescribers miss potentially dangerous drug pairs
Date:7/13/2009

Tucson, Ariz.Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.

These findings raise concern because of the high number of drugs Americans take: an average of 2.3 medications is prescribed during each physician office visit.

A synopsis of the research was published in May Research Activities (http://www.ahrq.gov/research/may09/0509RA4.htm), a digest of research findings intended to contribute to the national policymaking process.

The researchers, led by Daniel Malone, PhD, professor at the UA College of Pharmacy, mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians' assistants and nurse practitioners.

Recipients were asked to classify 14 drug pairs as "contraindicated," "may be used together but with monitoring" or "no interaction." Respondents could also state that they were "not sure."

For the drug pairs, one commonly prescribed medication was matched with another commonly prescribed medication.

The 950 respondents classified 42.7 percent of all drug combinations correctly.

Of the 14 drug pairs presented, four of them were contraindicated, meaning they should not be used together. A majority of prescribers correctly identified only one of the four pairs as contraindicated.

Moreover, for half of the 14 drug pairs, more than one-third of the respondents answered that they were "not sure," and two of these drug pairs were contraindicated.

"The study found a very low rate of recognition of these particular interactions," says Malone, "and some of these interactions are very common."

Use of several of the contraindicated drug pairs could be dangerous. For example, taking sildenafil (Viagra) and nitrates, such as isosorbide mononitrate, can be life-threatening.

According to Malone, the research indicates that health professional programs are not doing enough to teach students about potential drug-drug interactions. Consequently, patients should be sure to tell their pharmacist of all the medications they are taking.


'/>"/>

Contact: Karin Lorentzen
lorentzen@pharmacy.arizona.edu
520-626-3725
University of Arizona, College of Pharmacy
Source:Eurekalert  

Related biology news :

1. Research shows skeleton to be endocrine organ
2. Newly created cancer stem cells could aid breast cancer research
3. Dominant cholesterol-metabolism ideas challenged by new research
4. Researchers identify proteins involved in new neurodegenerative syndrome
5. Texas researchers and educators head for Antarctica
6. MGH researchers describe new way to identify, evolve novel enzymes
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
9. U of MN researchers discover noninvasive diagnostic tool for brain diseases
10. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
11. Story ideas from the Journal of Lipid Research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UA pharmacy research shows prescribers miss potentially dangerous drug pairs
(Date:3/9/2016)... , March 9, 2016 This BCC Research ... states of the RNA Sequencing (RNA Seq) market for ... as instruments, tools and reagents, data analysis, and services. ... segments of the RNA-Sequencing market such as RNA-Sequencing tools ... the main factors affecting each segment and forecast their ...
(Date:3/8/2016)... N.C. , March 8, 2016   ... sensor technology, today announced it has secured $11M ... by GII Tech, a new venture fund being ... with additional participation from existing investors TDF Ventures ... the funds to continue its triple-digit growth and ...
(Date:3/3/2016)... DE SOTO, Kansas , March 3, 2016 /PRNewswire/ ... offer Oncimmune,s Early CDT®-Lung, a blood test to ... lung cancer Early CDT®-Lung test to its ... --> Early CDT®-Lung test to its clients which ... Oncimmune, a leader in early cancer detection, today announced ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... Hill, Conn. (PRWEB) , ... April 28, 2016 ... ... of financing and ongoing support for Connecticut's innovative, growing companies, today announced the ... digital health and financial technology (fintech) companies. , “VentureClash looks to ...
(Date:4/28/2016)... ... 28, 2016 , ... Morris Midwest ( http://www.morrismidwest.com ), a ... at its Maple Grove, Minnesota technical center, May 11-12. The event will ... Almost 20 leading suppliers of tooling, accessories, software and other related technology will ...
(Date:4/27/2016)... ... April 27, 2016 , ... The Pittcon Organizing Committee is pleased to ... been a volunteer member of Committee since 1987. Since then, he has served in ... treasurer and was chairman for both the program and exposition committees. In his professional ...
(Date:4/27/2016)... Md. and RESEARCH TRIANGLE PARK, ... Corporation (NASDAQ: UTHR ) announced today that ... Officer, of United Therapeutics will provide an overview and ... 41 st Annual Health Care Conference. ... 2016, at 10:00 a.m. Eastern Time, and can be ...
Breaking Biology Technology: