Navigation Links
U of MN researchers discover noninvasive diagnostic tool for brain diseases
Date:8/22/2007

Researchers from the University of Minnesota Medical School and Brain Sciences Center at the Minneapolis VA Medical Center have identified a noninvasive and painless way to diagnose complex brain diseases. And its as simple as staring at a point of light. The research offers promise for a less-stressful, painless, and objective diagnosis for brain diseases, as well as a way to measure the effectiveness of different treatments for these diseases. Using magnetoencephalography (MEG) to record tiny magnetic fields in the brain, the researchers recorded brain cells communicating with each other while research subjects stared at a point of light.

After applying various mathematic algorithms, the researchers were able to classify the 142 research subjects by diagnosis. Study participants fell into one of six categories, including people with Alzheimers disease, chronic alcoholism, schizophrenia, multiple sclerosis or Sjogrens syndrome, as well as healthy controls.

The research, led by Apostolos P. Georgopoulos, M.D., Ph.D., professor of neuroscience, neurology, and psychiatry, will be published in the Aug. 27, 2007 issue of the Journal of Neural Engineering. This elegantly simple test allows us to glimpse into the brain as it is working, Georgopoulos said. We were able to classify, with 100 percent accuracy, the various disease groups represented in the group of research subjects. There are no good tests that measure the brain as it functions. Several tests exist to assess brain structure, but they reveal little of how the brain interacts. Currently, brain-related diseases are diagnosed with a combination of behavioral exams, psychiatric interviews, and neuropsychological testing, all which take time and can be hard on the patient, Georgopoulos said. This discovery gives scientists and physicians another tool to assess peoples disease progression, he said. In the future it could be applied when studying the effect of new treatments or drug therapies.

All behavior and cognition in the brain involves networks of nerves continuously interactingthese interactions occur on a millisecond by millisecond basis. The MEG has 248 sensors that record the interactions in the brain on a millisecond by millisecond basis, much faster than current methods of evaluation such as the functional magnetic resonance imaging (fMRI), which takes seconds to record. The measurements they recorded represent the workings of tens of thousands of brain cells.

Georgopoulos and his team were inspired to try to use the MEG as a diagnostic tool after discovering that neural interactions across human subjects were very similar. The team published on this novel way to assess the dynamic interactions of brain networks acting in synchrony in a 2006 issue of the Proceedings of the National Academy of Sciences. Now the team will continue to collect more data on the six disease groups, as well as begin to analyze research subjects with other brain diseases, including depression, post-traumatic stress disorder, autism, and Parkinsons disease, to see if the same technique can be applied.


'/>"/>
Contact: Sara E. Buss
buss@umn.edu
612-626-7037
University of Minnesota
Source:Eurekalert

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. NYU researchers simulate molecular biological clock
5. Researchers reveal the infectious impact of salmon farms on wild salmon
6. Researchers identify target for cancer drugs
7. Vital step in cellular migration described by UCSD medical researchers
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. UCSD researchers maintain stem cells without contaminated animal feeder layers
10. Researchers discover molecule that causes secondary stroke
11. Researchers find missing genes of ancient organism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:4/4/2017)... 2017   EyeLock LLC , a leader of ... States Patent and Trademark Office (USPTO) has issued U.S. ... of an iris image with a face image acquired ... company,s 45 th issued patent. ... given the multi-modal biometric capabilities that have recently come ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... (PRWEB) , ... June 22, 2017 , ... ... superior results to clients throughout the biopharma and life sciences industries, continue to ... industry is seeing. Tunnell’s Kip Wolf will be speaking on “The State of ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... CTNext board of directors has formed a Higher Education Entrepreneurship Advisory Committee to ... of institution presidents and other high-ranking representatives from 35 higher education institutions across ...
(Date:6/20/2017)... ... 2017 , ... National executive search firm, Slone Partners, announces ... and biomarker expertise, as VP of Scientific Affairs at Cambridge Biomedical. , ... development and sample testing services. The organization acts as a leading provider of ...
(Date:6/19/2017)... ... June 19, 2017 , ... EDETEK, Inc., ... today that it is launching two new additions of its award-winning cloud-based platform ... capabilities at the DIA 2017 Annual Meeting in Chicago, IL, June 19-22, 2017. ...
Breaking Biology Technology: