Navigation Links
U of M researchers utilize genetically corrected stem cells to spark muscle regeneration
Date:3/5/2013

t mice with fully functional muscle stem cells.

This latest project from the U of M provides the proof-of-principle for the feasibility of combining induced pluripotent stem cell technology and genetic correction to treat muscular dystrophy.

"Utilizing corrected induced pluripotent stem cells to target this specific genetic disease proved effective in restoring function," said Antonio Filareto, Ph.D., a postdoctoral fellow in Perlingeiro's laboratory and the lead author on the study. "These are very exciting times for research on muscular dystrophy therapies."

These studies pave the way for testing this approach in reprogrammed human pluripotent cells from muscular dystrophy patients.

According to Perlingeiro, "Developing methods to genetically repair muscular dystrophy in human cells, and demonstrating efficacy of muscle derived from these cells are critical near-term milestones, both for the field and for our laboratory. Testing in animal models is essential to developing effective technologies, but we remained focused on bringing these technologies into use in human cells and setting the stage for trials in human patients."


'/>"/>

Contact: Caroline Marin
crmarin@umn.edu
612-624-5680
University of Minnesota Academic Health Center
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Researchers id queens, mysterious disease syndrome as key factors in bee colony deaths
2. Study led by NUS researchers proves the existence of 3 overstretched DNA structures
3. U of M researchers identify genetic variation behind acute myeloid leukemia treatment success
4. 3 Johns Hopkins researchers recognized for medical inventions
5. University of Alberta researchers bake a better loaf of bread
6. Researchers at IRB Barcelona discover a general mechanism that accelerates tumor development
7. Brown University researchers build robotic bat wing
8. Researchers say sunlight yields more efficient carbon dioxide to methanol model
9. Researchers decipher modus operandi of potential Alzheimers drug
10. Stanford researchers develop tool for reading the minds of mice
11. Researchers in Manchester find genetic key to preventing spine tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/17/2013)... foundations with more modern elements. Using this same approachbut ... Dietrich School of Arts and Sciences have designed a ... storage, and gas transport more efficient and at a ... issue of the Journal of the American Chemical ... builds upon Pitt Associate Professor of Chemistry Nathaniel Rosi,s ...
(Date:6/17/2013)... supplementation may help delay early onset of puberty in ... presented Monday at The Endocrine Society,s 95th Annual Meeting ... between the ages of 10 and 14. Boys undergo ... of age. Precocious puberty is diagnosed in girls when ... boys, it is diagnosed when these changes occur before ...
(Date:6/17/2013)... A Kansas State University research associate has received a ... ways to prevent the spread of malaria. , Bart ... Institutes of Health,s National Research Service Award Individual Postdoctoral ... the seventh Kansas State University researcher to receive the ... currently hold such an award. , Bryant, a university ...
Breaking Biology News(10 mins):'Chemical architects' build materials with potential applications in drug delivery and gas storage 2Vitamin D supplementation may delay precocious puberty in girls 2NIH fellowship helps researcher fight malaria, understand mosquito immunity 2
... of spring, like budding trees, are worth celebrating. But ... fertile, winged termites swarming furiously to scatter and search ... Orleans, as the swirling, airborne masses of termites become ... are busy developing a biopesticide that could someday knock ...
... imaging technologies allow physicians to visualize more of the ... not previously seen, but seeing more may have little ... , The study included 198 patients with suspected pulmonary ... multidetector CT (MDCT) examination; 100 patients had a single-detector ...
... first active vaccine that can significantly delay and possibly prevent ... similar to mad cow disease. The new findings, published online ... for the development of a vaccine to prevent a group ... prions. , Although no cure for these diseases -- which ...
Cached Biology News:Fungus Effective Against Winged Termites 2Newer imaging techniques may lead to over-treatment 2Active Vaccine Prevents Mice From Developing Prion Disease 2Active Vaccine Prevents Mice From Developing Prion Disease 3
(Date:6/18/2013)... 2013 Tabletop SEMs are inexpensive and ... have limited performance and capability such as small sample ... would normally provide better imaging performance and more analytical ... have a higher cost of maintenance. The Pemtron ... these two types of SEM product, offering competitive prices ...
(Date:6/18/2013)... (PRWEB) June 18, 2013 ExakTime, ... in North America, has introduced AccountLinx Plus, a ... payroll records between ExakTime’s software and industry-leading payroll ... software setup and keeps employee databases up-to-date in ... a business’ current payroll software, directly into ExakTime’s ...
(Date:6/18/2013)... DuPont welcomes 48 of the nation’s ... National AgriScience Teachers Ambassador Academy this week (NATAA) at ... , The NATAA “Ag Academy” is a ... special project of the National FFA Foundation ... . The highly recommended agriscience teachers, who are ...
(Date:6/18/2013)... -- regulated information — Global biopharmaceutical company UCB, Inc. and ... launch of a new Pledge campaign for people with ... empowers the millions of Americans living with ... commitment to demand more: greater understanding of the condition, ... partial-onset seizure control.  More information is available at ...
Breaking Biology Technology:Nanounity Introduces the Pemtron Range of Compact Scanning Electron Microscopes 2Nanounity Introduces the Pemtron Range of Compact Scanning Electron Microscopes 3ExakTime Introduces AccountLinx Plus 2DuPont Sponsors National AgriScience Ambassador Academy 2DuPont Sponsors National AgriScience Ambassador Academy 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 2Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 4Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 5Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 6
... CRN says , CRN magazine ranked Laurie Benson, ... the top 25 executives in 2004. The magazine looked for ... Benson ranked among executives from IBM, Cisco, Intel, Sun and ... Infosecurity Conference , Milwaukee PKWare s ...
... cooperative that networks Wisconsin institutions, took different directions in ... eWeek last September, the magazine has reported. , ... than 30 respondents and choosing six for evaluation, eWeek ... enough to provide anti-spam services to all of WiscNets ...
... , ,Now what? Everyone thinks I have some cushy ... secretary at the Department of Health and Human Services, but ... don't realize that federal ethics rules basically keep Cabinet secretaries ... next would have meant staying inside the Bush administration. The ...
Cached Biology Technology:WiscNet members choose anti-spam products for different needs 2Reading Tommy Thompson's mind – life after public service 2Reading Tommy Thompson's mind – life after public service 3
... Rat adult normal paraffin tissue array ... or proteins of interest in extensive ... Rat brain, heart, kidney, liver, ... are arrayed on positively charged glass ...
Rat Normal Multiple Tissue Array 1 slide...
... DeStreak Reagent, 1 ml. ... 2-D gels by preventing streaking.Eliminates ... oxidation of proteins.Stabilizes proteins throughout ... simplified, well-resolved protein patterns.Ideal for ...
Request Info...
Biology Products: