Navigation Links
U of M researchers unveil nation's first porcine virus rapid detection test

MINNEAPOLIS/ST. PAUL (July 23, 2013) Mere months after porcine epidemic diarrhea virus (PEDV) was first confirmed in the United States swine population, University of Minnesota researchers have developed a PEDV rapid diagnostic test.

The first-of-its-kind test, which is available now, provides a way to quickly and cost-effectively identify the presence of U.S. PEDV strains.

Characterized by acute diarrhea and vomiting, a PEDV outbreak wipes out an average of 50 percent of young swine at newly affected farms. PEDV poses no risk to other animal or human health and no risk to food safety. Should PEDV become widespread, however, the pork industry could suffer significant losses. The virus has been confirmed in sixteen U.S. states so far. There is no known vaccine or treatment for the virus at this time.

Thanks to the new test, samples from animals suspected of carrying PEDV can be submitted to the University of Minnesota Veterinary Diagnostic Laboratory (VDL) for testing. Test results are known within 24 hours, allowing for swine producers and farmers to take necessary precautions to prevent further spread. Genetic material is also extracted from the samples, which can be tested and tracked to monitor PEDV spread.

Samples including swine fecal swabs, saliva, serum, feed, and fecal, intestinal and lung tissues can be tested via a multiplex assay which identifies the presence of not just PEDV, but also transmissible gastroenteritis (TEG) a virus that has existed among U.S. swine populations for some time. Pairing the tests improves affordability to agriculture by bringing the cost of the test to less than $50.

"The University of Minnesota has been preparing for the arrival of an infectious disease like PEDV by making strategic investments over past 10-20 years," said James Collins, D.V.M., Ph.D., director of the VDL, professor in the College of Veterinary Medicine, and expert in food animal diagnostic medicine and infectious disease. "Agriculture is such an important part of what we do in Minnesota and thanks to preparation and the help of our partners, we were able to mobilize available resources and technology quickly to turn around a new test in just a few months. In our mind, the point where research can move this quickly is the pinnacle of where we need to be."

In addition to development of the test, the U of M team has completed sequencing the DNA of one strain of U.S. PEDV. The sequence has been deposited into the GenBank database in the National Center for Biotechnology Information to help amplify the research potential of new PEDV genome understanding.

Development of a cost-effective bioassay to determine whether PEDV is being spread via non-genetic materials including feedstuffs is ongoing at the University. Investigations aim to both identify the presence of PEDV and determine whether it is alive and active, thus posing a risk. The U of M, in collaboration with the United States Department of Agriculture and National Pork Producers Association, also continues to investigate how PEDV first entered the U.S. and further ways to best limit it's spread.

"This is an important new disease that's entered the U.S. and we have to try to mitigate its damage. The University of Minnesota is working diligently to help address the problem," said Collins.


Contact: Miranda Taylor
University of Minnesota Academic Health Center

Related biology news :

1. Researchers reveal the clearest new pictures of immune cells
2. Researchers describe potential for MERS coronavirus to spread internationally
3. U of M researchers identify new functions for autoimmune disease risk gene
4. Solving DNA puzzles is overwhelming computer systems, researchers warn
5. Antiviral enzyme contributes to several forms of cancer, University of Minnesota researchers say
6. Carnegie Mellon researchers develop artificial cells to study molecular crowding and gene expression
7. Researchers perform DNA computation in living cells
8. Memorial Sloan-Kettering researchers develop new method for tracking cell signaling
9. Researchers create method to rapidly identify specific strains of illness
10. Stanford researchers say peak oil concerns should ease
11. MU researchers find condition in dogs that may help further research into human disease
Post Your Comments:
(Date:11/10/2015)... 2015  In this report, the biomarkers ... product, type, application, disease indication, and geography. ... are consumables, services, software. The type segments ... efficacy biomarkers, and validation biomarkers. The applications ... development, drug discovery and development, personalized medicine, ...
(Date:11/2/2015)... , Nov. 2, 2015  SRI International has ... to provide preclinical development services to the National Cancer ... SRI will provide scientific expertise, modern testing and support ... of preclinical pharmacology and toxicology studies to evaluate potential ... --> The PREVENT Cancer Drug Development Program is ...
(Date:10/29/2015)... health pioneer, Joseph C. Kvedar , MD, describes ... wellness, and the business opportunities that arise from it ... Healthy Things . Long before health and wellness ... vice president, Connected Health, Partners HealthCare, was creating a ... the hospital or doctor,s office into the day-to-day lives ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015 According to two new ... 2005. This is something that many doctors, scientists, and public ... questions remains: with fewer PSA tests being done, will there ... Dr. David Samadi, "Despite the efforts made ... remains the second leading cancer cause of death in men, ...
(Date:11/23/2015)... China Cord Blood Corporation (NYSE: CO ) ("CCBC" ... collection, laboratory testing, hematopoietic stem cell processing, and stem ... results for the second quarter and first half of ... --> --> Second Quarter of ... quarter of fiscal 2016 increased by 12.7% to RMB171.5 ...
(Date:11/23/2015)... The royalty-free a greement ... develop daclatasvir for 112 low- and m ... --> --> The Medicines Patent Pool (MPP) ... signing an agreement with Bristol-Myers Squibb for daclatasvir, a novel ... of the HCV virus.  The royalty-free licence will enable generic ...
(Date:11/23/2015)...  CryoLife, Inc. (NYSE: CRY ), a leading medical ... surgery, announced today that it will participate in the upcoming ... December 2, 2015 at The New York Palace Hotel in ... Mackin , President and Chief Executive Officer. --> ... --> A live webcast of the Company,s presentation ...
Breaking Biology Technology: