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U of M research uncovers gene's contribution to asthma susceptibility
Date:9/23/2013

t various asthma susceptibility genes including ORMDL3, the better positioned we will be to strategize new treatment options."

The discovery provides momentum for future understanding of the pathogenesis of asthma and role of genetics in inflammatory allergic reactions. This research is not only relevant for asthma but potentially other allergic disorders such as those of the GI tract and skin. The American Academy of Allergy, Asthma & Immunology estimates the number of asthma suffers internationally at 300 million with 250,000 annual deaths attributed to the disease.

Genetic disposition can influence the severity or susceptibility to an asthmatic reaction to allergens or environmental factors such as stress and cold.

The ORMDL3 gene studied by U of M researchers has been linked to asthma in various ethnic groups worldwide.


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Contact: Miranda Taylor
tayl0551@umn.edu
612-626-2767
University of Minnesota Academic Health Center
Source:Eurekalert

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