Navigation Links
U-M researchers receive largest single collection of psoriasis DNA samples

ANN ARBOR, Mich.Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the release of the first National Psoriasis Victor Henschel BioBank DNA samples for use in research at the University of Michigan Health System; research that hopes to uncover the unknowns about the genetics of psoriasis and psoriatic arthritis.

A disabling and disfiguring disease of the immune system that appears on the skin, psoriasis is the most common autoimmune disease in the country, affecting as many as 7.5 million Americans, yet it is one of the most under-researched. Up to 30 percent of people with psoriasis develop psoriatic arthritis, a related joint disease.

"Because we will be studying many thousands of genes, and because the genetic differences that predispose people to psoriasis can be subtle, this type of research requires thousands of cases and controls to yield statistically significant results," says James T. Elder, M.D., Ph.D., the Kirk D Wuepper Professor of Molecular Genetic Dermatology. "That's why the large number of Biobank samples is so important."

In the past few years, new discoveries into the hereditary factors of psoriasis have been unveiled. The National Psoriasis Victor Henschel BioBank is a collection of DNA samples and clinical information used by scientists to advance the field of psoriasis genetics--to fill the gap between what is known about psoriasis genetics and what's not.

Elder and his team of researchers received the first 1,250 BioBank DNA samples today. They will use the samples to identify new genes that increase a person's risk factor for developing psoriasis, and examine the connection between psoriasis and other autoimmune diseases, such as Crohn's disease, rheumatoid arthritis and lupus. Additional BioBank DNA samples will be given to Elder in the coming months.

"It's also very important that the diagnosis of psoriasis is definite, especially when it comes to psoriatic arthritis. The Biobank patients have all been carefully examined by dermatologists and rheumatologists, and provide an outstanding clinical resource," Elder adds.

The National Psoriasis Victor Henschel BioBank is a collection of DNA samples and clinical information used by scientists to advance the field of psoriasis genetics. Once completed, it will be the largest single collection of psoriasis DNA samples in the world.

"The BioBank is a critical resource for bringing us one step closer to a cure for psoriasis, and we are honored to partner with Dr. Elder and his team on this landmark project," says Rick Seiden, chair of the National Psoriasis Foundation Board of Trustees. "This endeavor would not be possible without the hundreds of people with and without psoriasis and psoriatic arthritis who donated DNA over the past four years, and we thank all of them for their huge contribution to psoriasis research."


Contact: Jessica Soulliere
University of Michigan Health System

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
(Date:10/1/2015)... Oct. 1, 2015  Biometrics includes diverse set ... body characteristics, such as fingerprints, eye retinas, facial ... of biometrics technology has been constantly increasing in ... five years. In addition to the most prominent ... recognition, other means of biometric authentication are rapidly ...
(Date:9/29/2015)... , Sept. 29, 2015 News ... productivity while also saving energy , Minimized design ... Low Power Active Mode and embedded Fujitsu PalmSecure authentication ... Fujitsu today shows that good things come ... refreshed models to its enterprise desktop and mobile portfolio. ...
(Date:9/28/2015)... , September 28, 2015 ... expected to reach USD 12.03 billion by 2020, growing ... Technological advancements such as Backside Illumination (BSI) technique to ... over the forecast period.      (Logo: ... of the chip to reduce loss and, thus, reduce ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... PARK, N.J. and SAN DIEGO ... (BASF) and Mast Therapeutics, Inc. have agreed to collaborate ...  Currently, excipient-grade poloxamer 188 NF, marketed by BASF under ... used in a variety of pharmaceutical and biological applications, ... Poloxamer 188 is the starting material for Mast,s lead ...
(Date:10/13/2015)... , Oct. 13, 2015  Generex Biotechnology Corporation ( ... a non-binding Letter of Intent (LOI) with MediTemp Ltd. (MediTemp) ... a proprietary cooling technology designed to improve sperm quality in ... United States and three million men in ... 44 diagnosed as infertile.  For 42% of those men, the ...
(Date:10/13/2015)... ... , ... Proove Biosciences, a commercial and research leader ... Keck Medicine of the University of Southern California (USC) Pain Center to ... Research Clinical Objectives Linking Genotypic and Phenotypic Association with Pain Outcomes) is one ...
(Date:10/12/2015)... ... October 12, 2015 , ... Spirax Sarco, the leader in products ... CSM-C 600 compact clean steam generator . This unit is a skid ... of HTM2031, HTM2010, and EN285 standards. The CMS-C 600 generator can produce up ...
Breaking Biology Technology: