Navigation Links
U-M researchers receive largest single collection of psoriasis DNA samples
Date:9/1/2010

ANN ARBOR, Mich.Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the release of the first National Psoriasis Victor Henschel BioBank DNA samples for use in research at the University of Michigan Health System; research that hopes to uncover the unknowns about the genetics of psoriasis and psoriatic arthritis.

A disabling and disfiguring disease of the immune system that appears on the skin, psoriasis is the most common autoimmune disease in the country, affecting as many as 7.5 million Americans, yet it is one of the most under-researched. Up to 30 percent of people with psoriasis develop psoriatic arthritis, a related joint disease.

"Because we will be studying many thousands of genes, and because the genetic differences that predispose people to psoriasis can be subtle, this type of research requires thousands of cases and controls to yield statistically significant results," says James T. Elder, M.D., Ph.D., the Kirk D Wuepper Professor of Molecular Genetic Dermatology. "That's why the large number of Biobank samples is so important."

In the past few years, new discoveries into the hereditary factors of psoriasis have been unveiled. The National Psoriasis Victor Henschel BioBank is a collection of DNA samples and clinical information used by scientists to advance the field of psoriasis genetics--to fill the gap between what is known about psoriasis genetics and what's not.

Elder and his team of researchers received the first 1,250 BioBank DNA samples today. They will use the samples to identify new genes that increase a person's risk factor for developing psoriasis, and examine the connection between psoriasis and other autoimmune diseases, such as Crohn's disease, rheumatoid arthritis and lupus. Additional BioBank DNA samples will be given to Elder in the coming months.

"It's also very important that the diagnosis of psoriasis is definite, especially when it comes to psoriatic arthritis. The Biobank patients have all been carefully examined by dermatologists and rheumatologists, and provide an outstanding clinical resource," Elder adds.

The National Psoriasis Victor Henschel BioBank is a collection of DNA samples and clinical information used by scientists to advance the field of psoriasis genetics. Once completed, it will be the largest single collection of psoriasis DNA samples in the world.

"The BioBank is a critical resource for bringing us one step closer to a cure for psoriasis, and we are honored to partner with Dr. Elder and his team on this landmark project," says Rick Seiden, chair of the National Psoriasis Foundation Board of Trustees. "This endeavor would not be possible without the hundreds of people with and without psoriasis and psoriatic arthritis who donated DNA over the past four years, and we thank all of them for their huge contribution to psoriasis research."


'/>"/>

Contact: Jessica Soulliere
jesssoul@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:4/18/2017)... a global expert in SoC-based imaging and computing solutions, has developed ... the company,s hybrid codec technology. A demonstration utilizing TeraFaces ® , ... showcased during the upcoming Medtec Japan at Tokyo Big Sight April ... Vegas Convention Center April 24-27. ... Click here for an image of the M820 ...
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
Breaking Biology News(10 mins):
(Date:8/11/2017)... ... 11, 2017 , ... “There is an increasing consumer call ... synthetic ingredients,” said Matt Hundt, President of Third Wave Bioactives. “Combining the strong ... know-how of Biorigin will allow us to bring truly novel fermented ingredient technologies ...
(Date:8/10/2017)... ... August 09, 2017 , ... ... applications in the clinic is here. The team at Capricor Therapeutics, Inc. utilized ... medium for clinical studies. , Dr. Travis Antes, head of analytical development ...
(Date:8/10/2017)... USA (PRWEB) , ... August 09, 2017 , ... ... partnered with four international biomedical optics laboratories — the Wellman Center for Photomedicine, ... Medical Laser Center Lübeck and the Beckman Laser Institute at University of California, ...
(Date:8/10/2017)... ... August 10, 2017 , ... CNA Finance Chief Research Analyst, ... on Next Group Holdings, Inc. and see's significant opportunity in the company's plans ... cannot engage in traditional banking services. According to industry estimates, approximately 103 million ...
Breaking Biology Technology: