Navigation Links
Turtle studies suggest health risks from environmental contaminants
Date:2/19/2008

The same chemicals that keep food from sticking to our frying pans and stains from setting in our carpets are damaging the livers and impairing the immune systems of loggerhead turtlesan environmental health impact that also may signal a danger for humans.

Jennifer Keller, a researcher at the National Institute of Standards and Technology (NIST) Hollings Marine Laboratory in Charleston, S.C., reported on Feb. 16 at the annual meeting of the American Association for the Advancement of Science (AAAS) that a scientific team monitoring the blood plasma of loggerhead turtles along the U.S. East Coast consistently found significant levels of perfluorinated compounds (PFCs). PFCs are used as nonstick coatings and additives in a wide variety of goods including cookware, furniture fabrics, carpets, food packaging, fire-fighting foams and cosmetics. They are very stable, persist for a long time in the environment and are known to be toxic to the liver, reproductive organs and immune systems of laboratory mammals.

Keller said that in a 2005 study,* PFC concentrations measured in the plasma of turtles found along the coast from Florida to North Carolina indicated that PFCs have become a major contaminant for the species. The levels of the most common PFC, perfluorooctane sulfonate (PFOS), were higher in turtles captured in the north than in the south. Data recently evaluated by NIST and College of Charleston graduate student Steven OConnell shows that this northern trend of higher PFOS concentrations continues up into the Chesapeake Bay.

Blood chemistry analyses of PFC-contaminated loggerheads suggested damage to liver cells and the suppression of at least one immune function which could lead to a higher risk of disease. To support the cause-effect relationship between PFCs and illness, the researchers exposed Western fence lizards to the same PFOS levels found in loggerheads in the wild. The lizards showed significant increases in an enzyme that indicates liver toxicity. They also had signs of suppressed immune function.

These findings, Keller said, indicate that current environmental PFC exposuresat concentrations comparable to those seen in human blood samplesare putting marine species at enhanced risk of health problems from reduced immunity and may suggest a similar threat to us.

Keller reported that a recently completed study** led by colleague Margie Peden-Adams of the Medical University of South Carolina that showed PFOS is toxic to the immune systems of mice at concentrations found both in loggerhead sea turtles and humans. The ability of the mouse immune system to respond to a challenge was reduced in half by PFOSand this occurred at the lowest level of the compound ever reported for a toxic effect.

If our immune systems have a similar sensitivity to PFOS, Keller explained, humans could be immunocompromised from current environmental exposure to PFOS.


'/>"/>

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology news :

1. Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths
2. Research shows loggerhead sea turtles threatened by small-scale fishing operations
3. RNA-based methods for developmental studies are featured in Cold Spring Harbor Protocols
4. Iowa State researcher studies how enzymes break down cellulose
5. New studies suggest brain overgrowth in 1-year-olds linked to development of autism
6. Experts from Stevens, Merck, publish joint paper, Biosynthetic Studies of Platensimycin
7. New studies on schizophrenia, depression, trauma and autism highlight annual meeting
8. NIH grants enable energy studies
9. 2 carotid artery stenting studies show results comparable to AHA guidelines
10. LSU professor studies army-ant-following birds
11. Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Turtle studies suggest health risks from environmental contaminants
(Date:6/9/2016)... innovation leader in attendance control systems is proud to announce the introduction of fingerprint ... sure the right employees are actually signing in, and to even control the opening ... ... ... Photo ...
(Date:6/3/2016)... June 3, 2016 ... Nepal hat ein ... hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und ... der Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche ... im Januar teilgenommen, aber Decatur wurde als ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... TORONTO , June 23, 2016 /PRNewswire/ - ... Ontario biotechnology company, Propellon ... the development and commercialization of a portfolio of ... cancers. Epigenetic targets such as WDR5 represent an ... contribute significantly in precision medicine for cancer patients. ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and technical consulting, provides a free webinar on Performing Quality Investigations: ... 2016 at 12pm CT at no charge. , Incomplete investigations are still a ...
Breaking Biology Technology: