Navigation Links
Tuning into cell signals that tell where sensory organs will form inside the ear
Date:8/27/2010

Researchers have tracked a cell-to-cell signaling pathway that designates the future location of the ear's sensory organs in embryonic mice. The scientists succeeded in activating this signal more widely across the embryonic tissue that becomes the inner ear. Patches of sensory structures began growing in spots where they don't normally appear.

The structures contained tufted cells, called hair cells, which respond to sound waves and other sensations, and additional nerve cells that amplify or code sounds for the brain to interpret.

The results suggest an avenue for further investigation in restoring hearing loss from nerve damage.

The findings are reported this week in the early online edition of Proceedings of the National Academy of Sciences by researchers Byron H. Hartman, Thomas Reh, and Olivia Bermingham- McDonogh of the Department of Biological Structure at the University of Washington (UW) in Seattle. All three are members of the UW Institute for Stem Cells and Regenerative Medicine. The senior author, Bermingham-McDonogh, is also an affiliate of the UW Virginia Merrill Bloedel Hearing Research Center.

"As the population ages," said Bermingham-McDonogh, "there's a great interest in discovering how to regenerate the inner ear sensory cells that we need for our hearing and balance. Both of these falter as we get older -- we get hard of hearing and unsteady on our feet -- due to accumulated destruction of the sensory cells in the inner ear."

The goal of their research is to develop ways to restore inner ear sensory hair cells in people who have lost them due to age, excessive noise or other toxic damage. The hair cells do not spontaneously recover after they are lost, and adult stem cells have not been found in the mammalian inner ear. In order to devise a way to restart hair cell formation in the adult ear, Bermingham-McDonogh's group is studying how hair cells are made in the first place during e
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Migraine sufferers: More difficulty tuning out visual stimuli?
2. Tuning in on cellular communication in the fruit fly
3. Road signs and traffic signals on DNA
4. Using a pests chemical signals to control it
5. Size matters: Eavesdropping on sexual signals
6. New tool helps scientists see molecular signals of eye disease before symptoms arise
7. Scientists sever molecular signals that prolific parasite uses to puppeteer cells
8. Depression associated with sustained brain signals
9. Montana State researcher discovers that bile sends mixed signals to E. coli
10. Baby monkeys receive signals through their mothers breast milk
11. Concurrent imaging of metabolic and electric signals in the heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tuning into cell signals that tell where sensory organs will form inside the ear
(Date:5/19/2015)... 2015  Technology is rapidly advancing, outpacing enterprises, ability ... cloud. Passwords and their management are soon to be ... specifications such as those developed by the FIDO Alliance™. ... presents for BYOD, COPE, IoT, and mobile payments, the ... In response to the call for ...
(Date:5/11/2015)... , May 11, 2015  Synaptics Incorporated ... human interface solutions, today announced the appointment of ... and Chief Financial Officer, reporting to Rick ... Synaptics, current Chief Financial Officer, Kathleen Bayless ... Mr. Ali brings extensive financial ...
(Date:5/7/2015)... GOTHENBURG, Sweden , May 7, 2015 /PRNewswire/ ... new touch fingerprint sensors, FPC1022 and FPC1035, FPC,s ... FPC1022 and FPC1035 are mainly considered for integration ... decreased size gives smartphone OEMs increased possibilities to ... portfolio. The decreased size also improves possibilities for ...
Breaking Biology News(10 mins):HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 2HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 3Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2
... been thought to be important only to translate a gene's ... evidence shows that tiny bits of RNA not used to ... in the development of cancers. , "Scientists have known for ... as microRNAs, is only supposed to happen at certain times ...
... producing embryonic-like cells from umbilical cord blood may substantially ... injuries and disabilities. The discovery made during a project ... Branch and the Synthecon Corporation in the United States ... reliable source of human stem cells for the first ...
... who take soy or herbal supplements, such as black ... care, says a Cornell University expert affiliated with the ... at Cornell, the land-grant institution of New York state. ... herbal medicines can increase or decrease breast cancer risk, ...
Cached Biology News:Once given 'no respect,' cells' tiny RNAS take driver's seat 2Once given 'no respect,' cells' tiny RNAS take driver's seat 3Researchers propose measures to curb lion attacks in Tanzania 2Women cautioned against using herbal supplements 2Women cautioned against using herbal supplements 3
(Date:5/21/2015)... Ontario (PRWEB) May 21, 2015 ... into an exclusive North American distribution agreement with ... testing system. , With more than 160 years ... products and services for laboratory and production facilities, ... operational excellence and differentiated services to enable science. ...
(Date:5/20/2015)... and Markets ( http://www.researchandmarkets.com/research/x4b7kw/top_technologies ) has announced ... Insights" report to their offering. Technical ... the Health and Wellness sector and has identified top ... in the year 2015. The research service provides an ... wellness technologies that are anticipated to have the highest ...
(Date:5/20/2015)...  Select Medical Corporation ("Select") (NYSE: SEM ... early termination of the waiting period under the ... amended, applicable to the acquisition of Concentra Inc. ... that Select has created with Welsh, Carson, Anderson & ... MJ Acquisition Corporation has signed a definitive purchase ...
(Date:5/20/2015)... Westport, CT (PRWEB) May 20, 2015 ... the 10th anniversary of its acquisition of Tiger-Sul. ... from Enersul (Calgary Alberta, Canada) in May 2005, H.J. ... line to build it into a comprehensive portfolio of ... the strength of H.J. Baker and the innovation of ...
Breaking Biology Technology:Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Top Technologies in the Health and Wellness Industry 2015 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3
... 19 Encorium Group, Inc. (Nasdaq: ENCO ), ... design, development, and management capabilities for clinical trials and ... companies, today announced that it has completed a private ... a private investor for an aggregate purchase price of ...
... will report findings today (Oct. 19) that demonstrate ... dramatically reduce cartilage degeneration. , The discovery by scientists ... a Massachusetts-based startup company, could result in a new ... , The study, by Gregory D. Jay, MD, PhD, ...
... BEIJING, Oct. 19 /PRNewswire-Asia-FirstCall/ -- China Medical Technologies,Inc. ... medical device,company that develops, manufactures and markets advanced in-vitro ... for its SPR-,based analysis system (the "SPR System") from ... , The SPR System utilizes ...
Cached Biology Technology:Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 2Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 3Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 4Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 5Lubris, Biomodels Report on Potential New Therapy for Osteoarthritis 2China Medical Technologies Announces the SFDA Approval for its SPR System 2China Medical Technologies Announces the SFDA Approval for its SPR System 3
... Antibody Epitope: aa 16-25 of human ... Recommended Storage: Store vial at -20 C ... For extended storage aliquot contents and freeze at -20 C ... Family: Other Sub-Family: ...
... ion exchange media are ... high binding capacity. The ... a strong cation exchanger ... of 120 micrometers. Fully ...
SCCRO (S-17)...
... Yeast Display Vector is specifically designed to ... surface of Saccharomyces cerevisiae. Displayed proteins can ... with known or putative ligands. pYD1 uses ... of two domains Aga1 and Aga2 to ...
Biology Products: