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Tumor microvesicles reveal detailed genetic information
Date:2/10/2011

veal oncogene expression in the original tumor," explains Leonora Balaj of MGH Neurology, the first author of the study.

High levels of retrotransposon-associated RNA sequences were also detected in tumor microvesicles, and the investigators found those microvesicles could transfer their contents into normal cells. "One of the most important functions of tumor-derived microvesicles may be modification of normal cells in the microenvironment to make them more supportive of tumor growth," says study co-author Xandra Breakefield, PhD, MGH Neurology and a professor of Neurology at Harvard Medical School.


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Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

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