Navigation Links
Tumor microenvironment helps skin cancer cells resist drug treatment
Date:7/4/2012

a targeted therapy available, it puts you on good footing to narrow in on specific factors that may be at play in drug resistance."

Several HGF/MET inhibitors are in clinical development or are FDA-approved for other indications, making clinical trials combining these inhibitors with BRAF inhibitors feasible in the future. In addition, researchers could follow the same approach taken by the team to screen other drugs currently in development, identifying mechanisms of resistance and ways to counter them even before treatment begins.

"Drug resistance should no longer surprise us," said Golub. "We're thinking about how to do this how to systematically dissect resistance much earlier in the drug development process so that by the time a new drug enters the clinic, we have a good sense of what the likely mechanisms of resistance will be and have a strategy to combat them."


'/>"/>

Contact: Haley Bridger
hbridger@broadinstitute.org
617-714-7968
Broad Institute of MIT and Harvard
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Researchers identify need to sample multiple tumor zones in breast cancer
2. Cancerous tumors deliver pro-metastatic information in secreted vesicles
3. Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
4. A single stem cell mutation triggers fibroid tumors
5. Immune-response genes affecting breast tumor eradication
6. TGen leads new National Institutes of Health study of brain tumors
7. Dental X-rays linked to common brain tumor
8. Nanotherapy: Treating deadly brain tumors by delivering big radiation with tiny tools
9. The loss of a protein makes jump the tumor to the lymph node
10. Sensitive test helps improve vaccine safety
11. Restoring streamside forests helps songbirds survive the winter in Californias Central Valley
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)... LOS ANGELES , March 23, 2015  In ... in Federal fraud case conviction losses. This figure accounts ... fraud, which, according to The Nilson Report, exceeds $11 ... an investigative tool after a crime has occurred. Investor ... Agent and polygraph expert Joe Paolella partnered ...
(Date:3/20/2015)... March 20, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, announces ... one of the products featured in 2015 "I Want ... 11:00 PM EST on the DIY Network.   ... Las Vegas , site of the 2015 International ...
(Date:3/17/2015)... , March 17, 2015 MedNet ... specializing in clinical study management systems, is pleased ... attendance at ARENA,s Outsourcing in Clinical Trials Southeast ... event provides an excellent forum for MedNet to ... and affordable software-as-a-service (SaaS) eClinical technology platform. ...
Breaking Biology News(10 mins):Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
... provided a new solution to an old debate on why species ... to be published online next week in the online open access ... genetic "noise" caused by a surprising degree of variation in gene ... found that when species hybridise, some of the variation in gene ...
... hydrothermal vents along the Mid-Cayman Rise has turned up ... team led by Woods Hole Oceanographic Institution (WHOI) in ... Sciences . The work was conducted as part of ... biologic, and chemical clues to the origins and evolution ...
... Spanish . Two good tips for preventing ... troughs and add chlorine to the water. That,s according ... the agency,s Animal Waste Management Research Unit in Bowling Green, ... a hydrologist at Bowling Green, and other colleagues. Stainless ...
Cached Biology News:What causes hybrid vigor? 2Expedition to Mid-Cayman Rise identifies unusual variety of deep sea vents 2Expedition to Mid-Cayman Rise identifies unusual variety of deep sea vents 3Expedition to Mid-Cayman Rise identifies unusual variety of deep sea vents 4Expedition to Mid-Cayman Rise identifies unusual variety of deep sea vents 5Dairy farmers can fight growing disease threat with chlorine and stainless steel 2
(Date:4/16/2015)... OSAKA, Japan , April 16, 2015 ... of Kyoto University and Takeda Pharmaceutical Company Limited ... to develop clinical applications of induced pluripotent stem ... mellitus, neurological disorders and cancer immunotherapy. The "Takeda-CiRA ... designed to expedite multiple research projects for drug ...
(Date:4/16/2015)... 2015 Cytokinetics, Incorporated (Nasdaq: CYTK) announced ... results on Thursday, April 30, 2015 at 4:00 PM ... host a conference call at 4:30 PM Eastern Time ... outlook for the future. , The conference call will ... homepage and in the Investor Relations section of Cytokinetics’ ...
(Date:4/16/2015)... Proove Biosciences , Inc. is pleased ... for the 2015 BIO International Convention. Hosted by ... Convention will take place June 15-18 at the Pennsylvania ... BIO contest, industry leaders will be voting for companies ... The community voting period began on April 14, 2015 ...
(Date:4/16/2015)... Grove, IL (PRWEB) April 16, 2015 ... the American Association for Cancer Research (AACR) annual ... the Pennsylvania Convention Center, starting Saturday, April 18, in ... AACR holds claim to title of the oldest and ... journals, provides fellowships and grants, and partners with survivors ...
Breaking Biology Technology:CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 2Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 3Regis Technologies Joins American Association for Cancer Research Annual Meeting 2
... ... HOUSTON, June 11 Cyberonics, Inc. (Nasdaq:,CYBX) today announced results for the ... Key results for the fourth quarter of fiscal 2008 compared to ... $33.9 million, an 8% increase from $31.4 million. -- Net earnings ...
... Facility to Generate Pipeline-Grade Renewable Natural Gas ... (RNG(R)) from Manure and Other Waste Products, ... EPG ), a leader in the renewable bioenergy industry,will ... Leche Estates,RNG(R) Facility with a ground breaking ceremony. The ...
... 11 Cardium Therapeutics,(Amex: CXM ) today ... http://www.anginaresearchstudy.com to provide patients, caregivers and,physicians with ... The AWARE study is evaluating the therapeutic effects ... (insufficient blood flow,within the heart muscle) and associated ...
Cached Biology Technology:Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 2Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 3Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 4Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 5Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 6Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 7Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 8Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 9Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 10Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 2Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 3Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 4Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 5Cardium Launches New AWARE Clinical Study Website 2Cardium Launches New AWARE Clinical Study Website 3Cardium Launches New AWARE Clinical Study Website 4Cardium Launches New AWARE Clinical Study Website 5Cardium Launches New AWARE Clinical Study Website 6Cardium Launches New AWARE Clinical Study Website 7
... Human Pathogenic Viruses The National ... preserves well characterised, authenticated human ... facility, and NCPV is able ... nucleic acids derived from them, ...
... 5 Fluorescein 6-Fam, Hex, ... 3 Fluorescein Tamra Black Hole ... 6-Fam, Hex, Tet Tamra, Joe ... Health Research Institute, New York Double labelled ...
... flexible and easy to use ... control all members of the ... features a clear and easy-to-follow ... setup, user-friendly and highly sophisticated ...
... is a highly purified preparation of the ... protease which recognizes the identical cleavage site ... similar enzymatic activity (1). Novagen&'s enzyme is ... yield the highest activity available, and is ...
Biology Products: