Navigation Links
Tulane receives $15 million NIH contract to develop vaccine and treatment for deadly fever

The National Institute of Allergies and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a five-year contract totaling $15,254,919 to Tulane University for its ongoing efforts to treat and prevent Lassa fever, an often deadly viral disease that threatens hundreds of thousands of people annually in West Africa and is classified as a potential bioterrorism threat.

The contract will include collaboration between Tulane; Scripps Research Institute; The Broad Institute; Harvard University; the University of California at San Diego; Boston University; Autoimmune Technologies, LLC; Corgenix Medical Corporation and various partners in West Africa.

Dr. James Robinson, professor of pediatrics at Tulane University School of Medicine and principal investigator of the program, said researchers plan to evaluate antibodies from patients who were infected by the Lassa virus and recovered, to see if those antibodies might play a role in the development of a vaccine or treatment for the illness.

"This study will result in a fundamental understanding of the mechanisms of antibody responses and how they neutralize the Lassa virus," Robinson said. "We have assembled a very strong and diverse group of institutions to collaborate on this project."

In some areas of Sierra Leone, up to 16 percent of people admitted to hospitals have Lassa fever. Lassa fever is also associated with occasional epidemics, during which the fatality rate can reach 50 percent.

But Dr. Robert Garry, professor of microbiology and immunology at Tulane, who serves as program manager of the contract, sees hope.

"We have been very pleased with the results of our research efforts over the past five years," he said. "The diagnostic products we have developed have been shown to be remarkably effective in clinical settings in Africa, and will not only have a meaningful impact on health care in that part of the world, but will also fill a critical gap in bioterrorism defense. Now under the new NIH award, we will move to the next level allowing us to better treat the disease, or ultimately prevent it altogether."

Another team member, Dr. Daniel Bausch, associate professor of tropical medicine at Tulane University School of Public Health and Tropical Medicine, says that the group intends to expand this program to address other important infectious agents such as Ebola, Marburg and other hemorrhagic fever viruses that are of concern to the public health and bioterrorism preparedness communities.


Contact: Arthur Nead
Tulane University

Related biology news :

1. Tulane receives grant to study limb regeneration
2. Carnegie Mellons John Kitchin receives early career award
3. Jedi Mind Receives Vast Media Coverage at CES in Las Vegas
4. University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium
5. GenWay Clinical Laboratory receives accreditation from College of American Pathologists
6. Editor of Springer classic human genetics reference receives prize
7. Lehigh University professor receives Astellas Award for arsenic groundwater remediation efforts
8. University of California, San Francisco, researcher receives ASBMB-Merck Award
9. IGC scientist receives prestigious EMBO installation grant
10. UT Southwestern receives $700,000 from HHMI to promote medical education of Ph.D. students
11. Einstein receives high-risk/high-reward cancer research funding
Post Your Comments:
(Date:10/29/2015)... 29, 2015 Daon, a global leader in ... released a new version of its IdentityX Platform ... North America have already installed IdentityX v4.0 ... a FIDO UAF certified server component as ... activate FIDO features. These customers include some of the ...
(Date:10/29/2015)... , Oct. 29, 2015  Connected health pioneer, ... the explosion of technology-enabled health and wellness, and the ... book, The Internet of Healthy Things ... or smartphones even existed, Dr. Kvedar, vice president, Connected ... health care delivery, moving care from the hospital or ...
(Date:10/29/2015)... , Oct. 29, 2015 Today, ... a partnership with 2XU, a global leader in ... a smart hat with advanced bio-sensing technology. The ... athletes to monitor key biometrics to improve overall ... partnership, the two companies will bring together the most ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... November 25, 2015 Studies reveal ... human plaque and pave the way for more effective treatment ... cats     --> ... diagnosed health problems in cats, yet relatively little was understood ... collaborative studies have been conducted by researchers from the WALTHAM ...
(Date:11/25/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS; TSX: ... prospects remain fundamentally strong and highlights the following ... received DSMB recommendation to continue the ZoptEC Phase ... the final interim efficacy and safety data ... men with heavily pretreated castration- and Taxane-resistant prostate ...
(Date:11/25/2015)... The Global Genomics Industry ... and in-depth study on the current state of ... ) , The report provides ... classifications, applications and industry chain structure. The Genomics ... including development trends, competitive landscape analysis, and key ...
(Date:11/24/2015)... N.J. (PRWEB) , ... November 24, 2015 , ... The ... the recipient of the 2016 USGA Green Section Award. Presented annually since 1961, the ... through his or her work with turfgrass. , Clarke, of Iselin, N.J., ...
Breaking Biology Technology: