Navigation Links
True blood: SLU scientist investigates clotting factors
Date:7/11/2012

ST. LOUIS -- Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

The National Heart Lung and Blood Institute awarded the four-year grant, which will allow Rezaie to continue studying how to maintain the delicate balance between the life-preserving and life-threatening activity of blood clotting.

"Blood clotting factors must be turned on and off at exactly the right time so a person does not bleed to death or die of an episode such as a heart attack, which is triggered by a blood clot," said Rezaie, who has engineered molecules that impose equilibrium on the delicate system.

Rezaie recently discovered that antithrombin, which is a molecule produced by the liver that turns off several proteins in the coagulation system, can block inflammation in the blood vessel wall. This inflammation can lead to heart disease as well as a violent, life-threatening reaction to blood infections called acute sepsis.

Rezaie is working on harnessing the anti-inflammatory activity of antithrombin to reduce the incidence and severity of heart disease and to save the lives of those who suffer from acute sepsis. He has studied the control of blood clotting factors for 23 years.

Blood carries nutrients and oxygen to the body's organs and tissues as well as the ordnance of immunityantibodies and white blood cellsthat defend organs and tissues from infection. Given these critical functions, it is essential that bodies preserve blood against loss from bleeding injuries.

Imbedded in blood is the chemistry to stop bleeding before too much blood is lost. Whenever small cuts or bruises occur, the blood at the site of injury rapidly mobilizes clotting factors that build a plug at the breech in the bloo
'/>"/>

Contact: Nancy Solomon
solomonn@slu.edu
31-497-778-017
Saint Louis University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Scientists join forces in call for action to save coral reefs
2. Scientists discover an epigenetic cause of osteoarthritis
3. New York University scientists discover possible treatment to reduce scarring
4. Scientists discover new trigger for immense North Atlantic plankton bloom
5. Atmospheric scientists release first bottom-up estimates of Chinas CO2 emissions
6. Stanford scientists find molecule to starve lung cancer and improve ventilator recovery
7. Scripps Florida scientists identify critical quality control for cell growth
8. Gladstone scientists identify critical process in stem cell development
9. Wholly water -- students and scientists gather at NTU to discuss water problem
10. Cancer scientists link ‘oncometabolite’ to onset of acute myeloid leukemia
11. Rensselaer scientists unlock some key secrets of photosynthesis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
True blood: SLU scientist investigates clotting factors
(Date:9/19/2014)... 2014 Nxt-ID, Inc. (Nasdaq: NXTD and ... the growing m-commerce market, updates the "Wocket in Your Pocket" celebrity ... and light middleweight weight classes, Vinny Pazienza (PAZ). ... Game of Thrones actor Ciaran Hinds and ... star Katey Sagal have been cast in Bleed ...
(Date:9/19/2014)... shows that legume plants regulate their symbiotic relationship ... are transmitted through the plant structure from leaves ... bacteria-holding nodules in the roots. This collaborative study ... for Basic Biology, the Graduate University for Advanced ... Resource Science in Japan. , Legumes, an ...
(Date:9/18/2014)... PULLMAN, Wash. - Washington State University researchers have developed ... sediment to power waste cleanup in rural areas. ... lead to an inexpensive and quick way to clean ... treatment plants while reducing pollution. , Professor Haluk ... College of Engineering and Architecture discuss the system in ...
Breaking Biology News(10 mins):NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 2NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 3For legume plants, a new route from shoot to root 2Researchers develop unique waste cleanup for rural areas 2
... Public Health Project Eating Among Teens (EAT) researchers ... of encouraging youth to eat breakfast regularly. Researchers ... body weight change in more than 2,200 adolescents, ... consumed a healthier diet and were more physically ...
... Schedule , The following schedule of press conferences ... Sciences Meeting. Press conferences may be added or dropped, ... change. All updates to this schedule will be announced ... Convention Center). Press conferences take place in the Press ...
... Bobev, assistant professor of chemistry and biochemistry, has ... Career Development Award. The highly competitive funding ... educational activities of faculty early in their careers, ... most likely to become the academic leaders of ...
Cached Biology News:U of M finds teens who eat breakfast daily eat healthier diets than those who skip breakfast 22008 Ocean Sciences Meeting -- media advisory 2 22008 Ocean Sciences Meeting -- media advisory 2 32008 Ocean Sciences Meeting -- media advisory 2 42008 Ocean Sciences Meeting -- media advisory 2 52008 Ocean Sciences Meeting -- media advisory 2 62008 Ocean Sciences Meeting -- media advisory 2 72008 Ocean Sciences Meeting -- media advisory 2 82008 Ocean Sciences Meeting -- media advisory 2 9UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 2UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 3
(Date:9/18/2014)... -- Research and Markets has announced the ... 2014" report to their offering. ... professional and in-depth study on the current state of ... provides a basic overview of the industry including definitions, ... market analysis is provided for the international markets including ...
(Date:9/18/2014)... ST. LOUIS , Sept. 18, 2014  U.S. ... portfolio by signing an exclusive license for technology developed ... to control gene expression in plants, including for applications ... species. The technology was developed under ... science officer at Kultevat and former president of the ...
(Date:9/18/2014)... /PRNewswire/ - Oncothyreon Inc. (NASDAQ: ONTY ) ... separate underwritten offerings of 10,000,000 shares of its Common ... per share, for expected gross proceeds of $20 million ... Stock at a price to the public of $2,000.00 ... Each share of Series A Convertible Preferred Stock is ...
(Date:9/18/2014)... OMICS Group International invites researchers, authors and ... ‘Open Access Week’ by actively contributing their research ... Journals from 20-26th October, 2014. , Pharmaceutical ... accelerating with a tremendous speed to provide improved ... industry is gearing with innovation and technological revolution ...
Breaking Biology Technology:Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3Kultevat obtains license of gene switch technology 2Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 2Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 3Pharma and Omics Journals to Address Global Challenges during Open Access Week 2Pharma and Omics Journals to Address Global Challenges during Open Access Week 3
... RNA Isolation Kit , , ... for molecular assays due to abundant genetic information as ... ease and simplicity of sample collection. RNA , ... MagMAX-96 Blood RNA Isolation Kit uses strong denaturing , ...
... of Long dsRNA for RNAi , ... dsRNA for RNAi experiments in non-mammalian systems can now be , ... The kit , is based on ... and includes reagents for transcription, nuclease digestion and , ...
... RNA later Tissue , ... the preservation of RNA in intact animal tissues, organs, and cells. , ... tissue , samples or to freeze samples ... Here we demonstrate that RNA later provides the , ...
Cached Biology Technology:Robust High Throughput RNA Isolation from Blood Samples 2Robust High Throughput RNA Isolation from Blood Samples 3Robust High Throughput RNA Isolation from Blood Samples 4RNAi in Non-Mammalian Cultured Cells 2RNAi in Non-Mammalian Cultured Cells 3RNAi in Non-Mammalian Cultured Cells 4RNAi in Non-Mammalian Cultured Cells 5RNAi in Non-Mammalian Cultured Cells 6RNAi in Non-Mammalian Cultured Cells 7RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 2RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 3RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 4
ExonBio Service provides one-stop recobinant protein shopping from cloning, expression and purification. Price including gene cloning....
TRBP1 Antibody...
Request Info...
Tracker Datamatrix TRxD reads any 1D and 2D barcodes within 0.5 seconds....
Biology Products: