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Trudeau Institute announces new discovery in battle against plague and bacterial pneumonias
Date:6/27/2011

odies. However, animal studies suggest that antibodies may not be enough to protect humans from pneumonic plague. The Smiley laboratory has shown that T cells can also fight plague. The lab previously demonstrated that an immunization with an experimental vaccine stimulates the production of T cells that provide partial protection against pneumonic plague. This vaccine consisted of a live but weakened version of the plague causing bacterium.

Live vaccines are often effective, but they can be difficult to license because they have the potential to grow within immunocompromised recipients and inadvertently cause disease.

Additionally, Dr. Smiley believes these studies may help us learn to combat other kinds of pneumonia: "Bacterial pneumonia is one of the most common causes of death in hospitals and, like plague, many of these pneumonias are caused by bacteria that we may need to combat with both antibodies and T cells."


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Contact: Karen Sharma
518-891-3080
Trudeau Institute
Source:Eurekalert  

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