Navigation Links
Trichoplax genome sequenced -- 'rosetta stone' for understanding evolution
Date:9/3/2008

New Haven, Conn. Yale molecular and evolutionary biologists in collaboration with Department of Energy scientists produced the full genome sequence of Trichoplax, one of nature's most primitive multicellular organisms, providing a new insight into the evolution of all higher animals.

The findings reported in the online edition of the journal Nature show that while Trichoplax has one of the smallest nuclear genomes found in a multi-cellular creature, it contains signature sequences for gene regulation found in more complex animals and humans. Further, it defines Trichoplax as a branching point of animal evolution.

"Trichoplax placozoans are animals that have only four body cell types and no structured organs. They represent descendents of the oldest multi-celled animal, perhaps older even than sponges," said author Stephen Dellaporta, professor of molecular, cellular and developmental biology at Yale.

This study shows that compared with the nuclear genome of humans that contains 3 billion base pairs, Trichoplax has only 98 million. Earlier sequencing work showed that the mitochondrial genome of Trichoplax is over twice the size of those found in most animals with genes, introns and spacer sequences like the most primitive organisms.

However, size is not all that matters. DNA sequences that organisms share in common represents what was in their genomes at the time of their divergence. Unlike other model systems for studying evolution, including fruit flies and worms, even the arrangement of genes is conserved between the Trichoplax and human genomes.

"Trichoplax shares over 80 percent of its genes with humans," said Dellaporta. "We are exited to find that Trichoplax contains shared pathways and defined regulatory sequences that link these most primitive ancestors to higher animal species. The Trichoplax genome will serve as a type of "Rosetta Stone" for understanding the origins of animal-specific pathways."


'/>"/>

Contact: Janet Rettig Emanuel
janet.emanuel@yale.edu
203-432-2157
Yale University
Source:Eurekalert  

Related biology news :

1. Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
2. Genome of saltwater creature could aid understanding of gene grouping
3. Cataloguing invisible life: Microbe genome emerges from lake sediment
4. Duke-NIEHS team shows how DNA repairs may reshape the genome
5. Significant impact factor boost for scientific journal Genome Research
6. Duckweed genome sequencing has global implications
7. US Department of Energy Joint Genome Institute announces new genome sequencing projects
8. Genome communication
9. Genome sequence of small marine creature sheds light on vertebrate origins
10. EuroDYNA takes lid off the genome
11. Brucella abortus S19 genome sequenced; points toward virulence genes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Trichoplax genome sequenced -- 'rosetta stone' for understanding evolution
(Date:1/11/2017)... Iowa , Jan. 11, 2017 Intoxalock, ... first with the release of its patent-pending calibration device. ... and reliably perform calibrations, securely upload data logs and ... for the customer. "Fighting drunk driving through ... for the public at large, but also for the ...
(Date:1/6/2017)... Jan. 5, 2017  SomaLogic announced today that ... Alliance" established by iCarbonX, the China ... a "Global Digital Health Ecosystem that can define ... of individual,s biological, behavioral and psychological data, the ... the companies, SomaLogic will provide proteomics data and ...
(Date:1/4/2017)... LAS VEGAS , Jan. 4, 2017 /PRNewswire/ ... in performance biometric sensor technology, today announced the ... Benchmark™ sensor systems, the highly-accurate biometric sensor ... ® biometric technology, experience and expertise. The ... of Benchmark designed specifically for hearables, and Benchmark ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... , Jan 19, 2017 Research and ... by Profiling Technology, Biomolecules, Cancer Type, Application - Global Opportunity Analysis ... ... forecasts that the global market is projected to reach $15,737 million ... 13% from 2016 to 2022. Omic technologies segment ...
(Date:1/19/2017)... LOUISVILLE, Ky. and HOUSTON ... Prenatal Inc. ("NX Prenatal") today announced the formation ... brings together leading clinicians and industry veterans who ... the company as it accelerates development of its ... positioned to provide medical, clinical and strategic guidance ...
(Date:1/19/2017)... , Jan 19, 2017 Research and Markets ... has announced the addition of ... Material, Application - Forecast to 2025" report to their ... The report provides a detailed analysis on current and ... forecasts till 2025, using estimated market values as the base numbers ...
(Date:1/19/2017)... Berkeley, CA (PRWEB) , ... January 19, 2017 ... ... the delivery of product vigilance software to leading biopharmaceutical and medical device manufacturers ... Mail is a fully 21 CFR Part 11-compliant email client designed to provide ...
Breaking Biology Technology: