Navigation Links
Trichinosis parasite gets DNA decoded
Date:2/20/2011

Scientists have decoded the DNA of the parasitic worm that causes trichinosis, a disease linked to eating raw or undercooked pork or carnivorous wild game animals, such as bear and walrus.

After analyzing the genome, investigators at Washington University School of Medicine in St. Louis and their collaborators report they have identified unique features of the parasite, Trichinella spiralis, which provide potential targets for new drugs to fight the illness. The research is published online Feb. 20 in Nature Genetics.

While trichinosis is no longer a problem in the United States fewer than a dozen cases are reported annually an estimated 11 million people worldwide are infected. Current treatments are effective only if the disease is diagnosed early.

"It takes less than two weeks for the larvae to travel from the intestine to muscle, where they live," says lead author Makedonka Mitreva, PhD, research assistant professor of genetics at Washington University's Genome Center. "Once the worms invade the muscle, drugs are less effective. While the disease is rarely deadly, patients often live for months or years with chronic muscle pain and fatigue until the worms eventually die."

Today, trichinosis occurs most often in areas of Asia and Eastern Europe where pigs are sometimes fed raw meat, and meat inspections are lax.

The new research also has implications far beyond a single parasitic disease, the researchers say. T. spiralis is just one of many thousands of parasitic roundworms called nematodes that, according to the World Health Organization, infect 2 billion people worldwide, severely sickening 300 million. Other species of parasitic nematodes cause diseases in pets and livestock and billions of dollars of crop losses annually.

Among nematodes, T. spiralis diverged early, some 600-700 million years before the crown species, C. elegans, a model organism used in research la
'/>"/>

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Scripps Florida scientists awarded $1.5M to fight major water and food parasites
3. Parasite-resistant peppers green alternatives to chemical pesticides
4. Malaria parasite zeroes in on molecule to enhance its survival, team finds
5. Reduction in parasite infections ahead for India
6. Researchers identify new way the malaria parasite and red blood cells interact
7. Locking parasites in host cell could be new way to fight malaria
8. Mosquito parasite may help fight dengue fever
9. Immune genes adapt to parasites
10. Study finds role for parasites in evolution of sex
11. Discovery to aid in future treatments of third-world parasites
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Trichinosis parasite gets DNA decoded
(Date:12/10/2014)... , Dec. 9, 2014  Valencell, a leader in ... seeing a staggering demand from its licensees for highly ... revealed, is not solely coming from fitness and health ... "A wearable is only as useful as ... is the ultimate driver in long-term mass consumer adoption ...
(Date:12/5/2014)... Calif. , Dec. 4, 2014 ... has boosted investments in new testing and inspection ... also given rise to a range of innovative ... the requirements of Generation Y, which is generally ... As a result, product development strategies of test ...
(Date:11/21/2014)... According to a new market ... RFID, Access Control, Intrusion Detection, Parking Management, Under Vehicle ... Service Geography - Global Forecasts to 2020", published by ... be around $25 Billion in 2014 and is expected ... CAGR of 8.69%. Browse 116 market data ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... Head, SCReactive oxygen species (ROS) occur as a ... by damaging proteins, nucleotides and lipids. Organisms ... the effects of ROS, and the oxidative stress ... performance declines with age due to lifetime accrual ...
... was launched simultaneously by Global Carbon Project co-chair Michael ... the USA at Capitol Hill, Washington by GCP Executive ... posted the most recent figures for the worlds, carbon ... added to the atmosphere, the underpinning of human induced ...
... Sept. 24, 2008 Calorie restriction, a diet that is ... as effective at extending life in people as it is ... Medicine in St. Louis. Previous research had shown ... food can live up to 50 percent longer. Because of ...
Cached Biology News:Researchers discover that growing up too fast may mean dying young in honey bees 2Researchers discover that growing up too fast may mean dying young in honey bees 3Growth in the global carbon budget 2Researchers note differences between people and animals on calorie restriction 2Researchers note differences between people and animals on calorie restriction 3
(Date:12/24/2014)... and NEW YORK , Dec. 24, ... a biopharmaceutical company advancing patient care in critical areas, ... 3,500,000 shares of common stock, and warrants to purchase ... at an offering price of $4.00 per share and ... exercise price of $5.00, are exercisable immediately, and expire ...
(Date:12/24/2014)... St. Louis, Missouri (PRWEB) December 23, 2014 ... and targeting Swiss biotechnology company, Syngenta, are in the ... for pretrial proceedings. The consolidated case is In Re: ... in the U.S. District Court for the District of ... litigation (MDL) has been handed over to U.S. District ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 According to Ross ... Island Affiliate of ITRA Global, the national office market continues ... recovery. This is evidenced by the third quarter’s surprising ... market. Low energy costs have held inflation down and ... negative is the housing market remaining soft. , This solid ...
(Date:12/24/2014)... December 23, 2014 Pipette.com announces their ... Twitter followers can submit their #HolidayInTheLab pictures for a ... lab mates. , For those struggling to think of ... Pipette.com Holiday in the Lab Contest provides the ideal ... followers to send pictures of their chemistree, holiday ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2
... , PHILADELPHIA, June 3 Waters Corporation (NYSE: ... American Society for Mass Spectrometry (ASMS) presented Prof. ... the first Ron Hites Award for Outstanding Research ... of Mass Spectrometry (JASMS). Prof. Ashcroft,s paper titled, ...
... , Sees opportunity to end abusive use of authorized ... June 3 Mylan Inc.,s (Nasdaq: MYL ... the U.S. House of Representatives Judiciary Subcommittee on Courts ... pharmaceutical companies and generic pharmaceutical companies. During her testimony, ...
... 3 The Gamida Cell-Teva Joint Venture,announced today that five prestigious ... Valencia, have joined the Excel study. , , ... Hospital Clinic of Barcelona, Barcelona, Principal Investigator, Dr. ... Valencia, Valencia, Principal Investigator, Dr. Cristina Arbona, MD, ...
Cached Biology Technology:First ASMS Hites Award for Outstanding Research Publication Presented to Prof. Alison Ashcroft for Her Use of Waters Synapt HDMS System to Explore Protein Complexes 2First ASMS Hites Award for Outstanding Research Publication Presented to Prof. Alison Ashcroft for Her Use of Waters Synapt HDMS System to Explore Protein Complexes 3Mylan Again Calls for an End to Authorized Generics During 180-Day Exclusivity Period 2Five Cord Blood Transplant Centers in Catalonia and Valencia Join a Study to Test a New Technique to Treat Leukemia and Lymphoma 2Five Cord Blood Transplant Centers in Catalonia and Valencia Join a Study to Test a New Technique to Treat Leukemia and Lymphoma 3
Request Info...
... The Zero Blunt ... for Sequencing is designed ... sequencing of blunt-end PCR ... provides 5-minute TOPO Cloning ...
... 1 kit. Convenient way to ... Conjugations are carried out under mild conditions ... Dyes are packaged in premeasured amounts and ... Category: Blotting & Labeling & Detection, Protein ...
...
Biology Products: