Navigation Links
Trichinosis parasite gets DNA decoded
Date:2/20/2011

Scientists have decoded the DNA of the parasitic worm that causes trichinosis, a disease linked to eating raw or undercooked pork or carnivorous wild game animals, such as bear and walrus.

After analyzing the genome, investigators at Washington University School of Medicine in St. Louis and their collaborators report they have identified unique features of the parasite, Trichinella spiralis, which provide potential targets for new drugs to fight the illness. The research is published online Feb. 20 in Nature Genetics.

While trichinosis is no longer a problem in the United States fewer than a dozen cases are reported annually an estimated 11 million people worldwide are infected. Current treatments are effective only if the disease is diagnosed early.

"It takes less than two weeks for the larvae to travel from the intestine to muscle, where they live," says lead author Makedonka Mitreva, PhD, research assistant professor of genetics at Washington University's Genome Center. "Once the worms invade the muscle, drugs are less effective. While the disease is rarely deadly, patients often live for months or years with chronic muscle pain and fatigue until the worms eventually die."

Today, trichinosis occurs most often in areas of Asia and Eastern Europe where pigs are sometimes fed raw meat, and meat inspections are lax.

The new research also has implications far beyond a single parasitic disease, the researchers say. T. spiralis is just one of many thousands of parasitic roundworms called nematodes that, according to the World Health Organization, infect 2 billion people worldwide, severely sickening 300 million. Other species of parasitic nematodes cause diseases in pets and livestock and billions of dollars of crop losses annually.

Among nematodes, T. spiralis diverged early, some 600-700 million years before the crown species, C. elegans, a model organism used in research la
'/>"/>

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Scripps Florida scientists awarded $1.5M to fight major water and food parasites
3. Parasite-resistant peppers green alternatives to chemical pesticides
4. Malaria parasite zeroes in on molecule to enhance its survival, team finds
5. Reduction in parasite infections ahead for India
6. Researchers identify new way the malaria parasite and red blood cells interact
7. Locking parasites in host cell could be new way to fight malaria
8. Mosquito parasite may help fight dengue fever
9. Immune genes adapt to parasites
10. Study finds role for parasites in evolution of sex
11. Discovery to aid in future treatments of third-world parasites
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Trichinosis parasite gets DNA decoded
(Date:12/22/2014)... 22, 2014  The 2014 Holiday Season may be the ... Intelligence reports that the long anticipated floodgates for consumer ... demand for smart phones, tablets, and wearable mobile devices ... 2.5 billion users with nearly 4.8 billion biometric devices ...
(Date:12/19/2014)... LaunchKey , the first decentralized mobile authentication and authorization ... era, today announced the close of $3 million in ... Metamorphic Ventures with participation from ENIAC Ventures, Crosslink Capital, ... has raised $4 million to date, and will use ...
(Date:12/17/2014)... N.C. , Dec. 16, 2014 Valencell, a ... its PerformTek biometric technology to industry leaders such as ... accurate, clinically validated, biometric wearable products. These products will ... in Las Vegas . ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... first top predators to walk on land were not afraid ... of Toronto Mississauga study has found. Graduate student and ... U of T Mississauga,s Department of Biology suggest that ... million and 272 million years ago, was the first terrestrial ...
... led by scientists at Case Western Reserve University, has ... (MRI) to pinpoint blood vessel plaques caused by atherosclerosis. ... method of identifying plaques vulnerable to rupturethe cause of ... doctors can identify only blood vessels that are narrowing ...
... from the University of California, San Diego School of ... broadly regulates how genetic information transcribed from DNA to ... the myriad of proteins necessary for life. The ... , help explain how a relatively limited number of ...
Cached Biology News:'Steak-knife' teeth reveal ecology of oldest land predators 2Nanoparticle pinpoints blood vessel plaques 2Nanoparticle pinpoints blood vessel plaques 3Global regulator of mRNA editing found 2
(Date:1/22/2015)... GEA Niro Soavi the leader in ... the PandaPLUS 2000, which is ideal for new applications ... cell disruption . This compact laboratory homogenizer is the ... food, food additives and ingredients as well as for ...
(Date:1/22/2015)... Crystal Diagnostics (CDx) Xpress System, a rapid ... AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. coli ... to as STEC or the “Big-6”) as well as Escherichia ... per 325 g of raw ground beef and raw beef ...
(Date:1/22/2015)... 22, 2015 Selexis SA, a serial ... Cell Banks (RCBs) used for drug discovery to commercial ... will include Next-Generation Sequencing (NGS) data packages. ... biologic manufacturing by ensuring the integrity of the gene, ...
(Date:1/22/2015)... GenoSpace , a precision medicine software company that has developed ... of genomic, imaging and other biomedical data in research and ... , CEO of Aspera, an IBM Company, to its board ... "We are pleased to welcome Michelle ...
Breaking Biology Technology:GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2
... NorthPoint Domain, an IC Sciences,company, announced today a ... Langone Medical Center to develop a comprehensive suite,of ... on a shared commitment to excellence in vascular ... clinicians with new,tools to inform, engage, and shepherd ...
... DD ),today announced the addition of Deepak ... Biotechnology Advisory Panel. They join the ranks of,six ... to the,broad area of biotechnology and its application ... a professor of Genetics and Vice Chancellor for ...
... Mass., May 5 PLC Systems Inc.,(Amex: PLC ) ... wire its,financial results for the first quarter ended March 31, ... company plans to host a,conference call to discuss those results ... call may be joined via telephone by dialing (800) 638-4930 ...
Cached Biology Technology:NorthPoint Domain and NYU Vascular Associates Partner to Develop New Generation of Care Delivery Informatics Instruments 2NorthPoint Domain and NYU Vascular Associates Partner to Develop New Generation of Care Delivery Informatics Instruments 3DuPont Strengthens Commitment to Responsible Science with New Biotech Advisory Panel Members 2DuPont Strengthens Commitment to Responsible Science with New Biotech Advisory Panel Members 3PLC Systems to Host First Quarter Conference Call on May 15, 2008 2
... Custom Processing Service enables scientists who do not ... analysis software to have their biological samples tested ... Its as easy as 1-2-3 Chose ... your samples from the S&S antibody menu. ...
... This exceptionally sensitive nucleic acid gel stain ... low background in gels, making it ideal for ... standard UV transilluminators. SYBR Green I nucleic ... capillary electrophoresis, real-time PCR assays and bandshift ...
... and his coworkers reported the ... vitro cultivation of Novikoff Hepatoma ... using,Basal Medium 5A and subsequently ... medium known as McCoy's 5A ...
Eagle's Ham's amino acids; EHAA...
Biology Products: